Difference between revisions of "HOXC-AS1"
| Line 6: | Line 6: | ||
===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
NR_047504 | NR_047504 | ||
| − | [[File:Expression of lncRNA HOXC-AS1 and HOXC6 in normal tissues and atherosclerotic plaques. | + | [[File:Expression of lncRNA HOXC-AS1 and HOXC6 in normal tissues and atherosclerotic plaques.gif|right|thumb|400px|'''Expression of lncRNA HOXC-AS1 and HOXC6 in normal tissues and atherosclerotic plaques.'''<ref name="ref1" />]] |
===Characteristics=== | ===Characteristics=== | ||
lncRNA HOXC-AS1 is located on chromosome 12 and its transcription position is nearby.<ref name="ref1" /> | lncRNA HOXC-AS1 is located on chromosome 12 and its transcription position is nearby.<ref name="ref1" /> | ||
Latest revision as of 02:35, 28 October 2017
Contents
Annotated Information
Approved Symbol
HOXC-AS1 (HOXC cluster antisense RNA 1)
Chromosome
12q13.13
RefSeq(supplied by NCBI)
NR_047504
Expression of lncRNA HOXC-AS1 and HOXC6 in normal tissues and atherosclerotic plaques.[1]
Characteristics
lncRNA HOXC-AS1 is located on chromosome 12 and its transcription position is nearby.[1]
Expression
Compared to normal renal arterial intima, HOXC-AS1 is downregulated in carotid atherosclerosis.[1] Ox-LDL can suppress the expression of lncRNA HOXC-AS1 and HOXC6 in THP-1 macrophages.[1]
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| qRT-PCR | 5′-CTGCGACACTTCCCCACC-3′ | 5′-CTACTT GCCCACGACCGA-3′[1] |
Function
Overexpression of HOXC-AS1 promotes expression of HOXC6 at mRNA and protein levels.
Labs working on this lncRNA
- Laboratory Medicine Center, Nanfang Hospital, Southern Medical University , Guangzhou, China .
- Department of Anesthesiology, Nanfang Hospital, Southern Medical University , Guangzhou, China .
- Department of Vascular Surgery, Nanfang Hospital, Southern Medical University , Guangzhou, China .
- Department of Cardiology, Nanfang Hospital, Southern Medical University , Guangzhou, China .
