Difference between revisions of "CLMAT3"
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Colorectal cancer patients displaying high expression levels of CLMAT3 more frequently developed liver metastases than those with low lncRNA-CLMAT3 expression levels, indicating that lncRNA-CLMAT3 may act as an oncogene.<ref name="ref1" /> | Colorectal cancer patients displaying high expression levels of CLMAT3 more frequently developed liver metastases than those with low lncRNA-CLMAT3 expression levels, indicating that lncRNA-CLMAT3 may act as an oncogene.<ref name="ref1" /> | ||
| − | ===Expression | + | ===Expression=== |
The levels of CLMAT3 in the cancerous tissues were 2.26-fold higher than those in the normal colorectal tissues (P<0.05). In addition, CLMAT3 expression was significantly higher in the patients with liver metastasis than in those without liver metastasis and in the patients with lymph node metastasis than in those without lymph node metastasis.<ref name="ref1" /> | The levels of CLMAT3 in the cancerous tissues were 2.26-fold higher than those in the normal colorectal tissues (P<0.05). In addition, CLMAT3 expression was significantly higher in the patients with liver metastasis than in those without liver metastasis and in the patients with lymph node metastasis than in those without lymph node metastasis.<ref name="ref1" /> | ||
Revision as of 06:38, 26 November 2017
Contents
Annotated Information
Approved Symbol
CLMAT3
Approved Name
colorectal liver metastasis associated transcript 3
Synonyms
SPARC-AS1
RefSeq(supplied by NCBI)
NR_109873
Disease
colorectal cancer
Characteristics
CLMAT3 is located on human chromosome 14 (chr14:101379770-101381326, hg19).
Function
The patients with tumors displaying high CLMAT3 expression exhibited shorter OS than the patients with tumors displaying low CLMAT3 expression. [1] Colorectal cancer patients displaying high expression levels of CLMAT3 more frequently developed liver metastases than those with low lncRNA-CLMAT3 expression levels, indicating that lncRNA-CLMAT3 may act as an oncogene.[1]
Expression
The levels of CLMAT3 in the cancerous tissues were 2.26-fold higher than those in the normal colorectal tissues (P<0.05). In addition, CLMAT3 expression was significantly higher in the patients with liver metastasis than in those without liver metastasis and in the patients with lymph node metastasis than in those without lymph node metastasis.[1]
Labs working on this lncRNA
- Department of Oncological Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People's Republic of China.[1]
- Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200000, People's Republic of China.[1]
