Difference between revisions of "MGAT3-AS1"
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===Characteristics=== | ===Characteristics=== | ||
| − | + | MGAT3-AS1 is an intronic antisense lncRNA, which is transcribed from a gene located in the genome on chromosome 22.<ref name="ref1" /> | |
===Expression=== | ===Expression=== | ||
| − | + | MGAT3-AS1 was significantly increased in these patients compared to healthy controls and disease controls.<ref name="ref1" /> | |
===Function=== | ===Function=== | ||
| − | + | MGAT3-AS1 can predicts the survival of AKI and thus has the biomarker potential of AKI (P <0.001).<ref name="ref1" /> | |
| − | + | MGAT3-AS1 is specifically enriched in hypoxic renal tubular epithelial cells.<ref name="ref1" /> | |
==Labs working on this lncRNA== | ==Labs working on this lncRNA== | ||
Revision as of 02:13, 27 November 2017
Contents
Annotated Information
Approved Symbol
MGAT3-AS1 (MGAT3 antisense RNA 1)
Synonyms
TapSAKI
Disease
acute kidney injury
Chromosome
22q13.1
RefSeq ID
NR_126469
Ensembl ID
ENSG00000227188
Characteristics
MGAT3-AS1 is an intronic antisense lncRNA, which is transcribed from a gene located in the genome on chromosome 22.[1]
Expression
MGAT3-AS1 was significantly increased in these patients compared to healthy controls and disease controls.[1]
Function
MGAT3-AS1 can predicts the survival of AKI and thus has the biomarker potential of AKI (P <0.001).[1] MGAT3-AS1 is specifically enriched in hypoxic renal tubular epithelial cells.[1]
Labs working on this lncRNA
- Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and Department of Medicine/Division of Nephrology and Hypertension, Hannover Medical School, Hannover,[1] Germany.
- Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and National Heart and Lung Institute, Imperial College London, London, UK. lorenzen.[1]
References
Sequence
>gi|704000385|ref|NR_126469.1| Homo sapiens MGAT3 antisense RNA 1 (MGAT3-AS1), long non-coding RNA
000001 GCTACTGGTG GTCATCGGGG ACGCAGATAT GTGTGTCTCC ATTTTGCAGA TGAGGACATG GAGGCCTCAA GAGGTTAAGT 000080
000081 GACTTGCTCA GCCACACACA GCTGATGGGA ATGAAACAGA CGGAAACGGA GACTCCCCAA GCTGACAGGC GGACTACAGA 000160
000161 TCTGGGGGTT CTGCTCCAGG CTCAACACAA GTGGCCTGGG CGAGGGAGGG CCTGGTAGAC CATGACACCC AGCATCGAGG 000240
000241 AATTCTGCTT CCCCAGCAGG CTCAGAAGGA AGAAGTCTGC TTCAGGGGCC AGGCCTGGTC AAAGACTCCA TCTTCCCTGG 000320
000321 ATGGCCAGAG TCAAATCCTT GCAAATCCCG TTCACCATGG AGCAGAGACG AGACCTATGT TACCCAGGCT GTATGTGAAT 000400
000401 TCCTGGACTC AAGCAATCCT CCCATCTCAG CCTCGTGAGT AGTTGGGACA AGTCTCACAC CACCATACCC AGCTTAATTT 000480
000481 AATTTGAATT TTAATAGC
000081 GACTTGCTCA GCCACACACA GCTGATGGGA ATGAAACAGA CGGAAACGGA GACTCCCCAA GCTGACAGGC GGACTACAGA 000160
000161 TCTGGGGGTT CTGCTCCAGG CTCAACACAA GTGGCCTGGG CGAGGGAGGG CCTGGTAGAC CATGACACCC AGCATCGAGG 000240
000241 AATTCTGCTT CCCCAGCAGG CTCAGAAGGA AGAAGTCTGC TTCAGGGGCC AGGCCTGGTC AAAGACTCCA TCTTCCCTGG 000320
000321 ATGGCCAGAG TCAAATCCTT GCAAATCCCG TTCACCATGG AGCAGAGACG AGACCTATGT TACCCAGGCT GTATGTGAAT 000400
000401 TCCTGGACTC AAGCAATCCT CCCATCTCAG CCTCGTGAGT AGTTGGGACA AGTCTCACAC CACCATACCC AGCTTAATTT 000480
000481 AATTTGAATT TTAATAGC
