Difference between revisions of "FLVCR1-AS1"
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===Approved Symbol=== | ===Approved Symbol=== | ||
FLVCR1-AS1 (FLVCR1 antisense RNA 1) | FLVCR1-AS1 (FLVCR1 antisense RNA 1) | ||
| + | [[File:Genomic structure, experimental verification, and dbEST representation of a novel gene,FLVCR1-AS1.png|right|thumb|400px|'''Genomic structure, experimental verification, and dbEST representation of a novel gene,FLVCR1-AS1.(A) Genomic context and structure of LQK1.(B) PCR amplification of FLVCR1-AS1 from cDNA libraries.(C) Summary of FLVCR1-AS1 expression.'''<ref name="ref1" />]] | ||
===Previous Symbols=== | ===Previous Symbols=== | ||
NCRNA00292 | NCRNA00292 | ||
===Synonyms=== | ===Synonyms=== | ||
LQK1 | LQK1 | ||
| − | |||
===Chromosome=== | ===Chromosome=== | ||
1q32.3 | 1q32.3 | ||
| Line 15: | Line 15: | ||
===Ensembl ID=== | ===Ensembl ID=== | ||
ENSG00000198468 | ENSG00000198468 | ||
| + | The GenBank accession numbers for FLVCR1-AS1 are AY030238 and AY030239.<ref name="ref1" /> | ||
| + | |||
| + | ===Characteristics=== | ||
| + | FLVCR1-AS1 is a novel 2-exon gene and it appears to have arisen after duplication of the hFLVCR locus.<ref name="ref1" /> | ||
| + | FLVCR1-AS1 has two transcripts and both exon 2 isoforms share the same polyA signal.(Figure A on the right) | ||
===Expression=== | ===Expression=== | ||
| + | FLVCR1-AS1 is expressed in a wide variety of tissues, including colon tumor, uterine tumor, placenta, lung tumor, brain tumor, neural tissue, fatal liver/spleen, bone marrow, aorta and kiney. <ref name="ref1" /> | ||
| − | === | + | ===Function=== |
| − | + | Both splice forms of the FLVCR1-AS1 cDNA encode identical 103 aa ORFs that include a 163 nt MER41D interspersed repeat.(Figure A on the right) <ref name="ref1" /> | |
| − | |||
==Labs working on this lncRNA== | ==Labs working on this lncRNA== | ||
Revision as of 14:13, 26 January 2018
Contents
Annotated Information
Approved Symbol
FLVCR1-AS1 (FLVCR1 antisense RNA 1)
Genomic structure, experimental verification, and dbEST representation of a novel gene,FLVCR1-AS1.(A) Genomic context and structure of LQK1.(B) PCR amplification of FLVCR1-AS1 from cDNA libraries.(C) Summary of FLVCR1-AS1 expression.[1]
Previous Symbols
NCRNA00292
Synonyms
LQK1
Chromosome
1q32.3
RefSeq ID
NR_027285
OMIM ID
610864
Ensembl ID
ENSG00000198468 The GenBank accession numbers for FLVCR1-AS1 are AY030238 and AY030239.[1]
Characteristics
FLVCR1-AS1 is a novel 2-exon gene and it appears to have arisen after duplication of the hFLVCR locus.[1] FLVCR1-AS1 has two transcripts and both exon 2 isoforms share the same polyA signal.(Figure A on the right)
Expression
FLVCR1-AS1 is expressed in a wide variety of tissues, including colon tumor, uterine tumor, placenta, lung tumor, brain tumor, neural tissue, fatal liver/spleen, bone marrow, aorta and kiney. [1]
Function
Both splice forms of the FLVCR1-AS1 cDNA encode identical 103 aa ORFs that include a 163 nt MER41D interspersed repeat.(Figure A on the right) [1]
Labs working on this lncRNA
- Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA 98195-7710, USA. [1]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Lipovich L, Hughes AL, King MC, Abkowitz JL, Quigley JG. Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus. Gene. 2002 Mar 20;286(2):203-13.
Sequence
>gi|224591396|ref|NR_027285.1| Homo sapiens FLVCR1 antisense RNA 1 (head to head) (FLVCR1-AS1), transcript variant 1, long non-coding RNA
000001 GAGAACTTCG GGAGGCGGGG GAGGAAAGCG GCCGGCGAGC GCTGGCTGAC ATTTTCCTGC CCGGAAGGAT GCATGGCCCG 000080
000081 GGGTCTCCTG CACCTGAGGG TGGGCGGGAG GCGGCCCCGC GGGTTGTGTT GCTGGAAAAA GGGGTCTCGA TCCAGACCCC 000160
000161 AAGAGAGGGT TCTTGGGTCT ACTTCAGGGA AGAATTGGAG GCGAGTCACA GAGCGCAGTG AAGGAAGCAA GTTTATTGGA 000240
000241 ATCTACTCCG TTAGAGAGTG CAAGTCCTCA GACTGCAGGA GGAGGAACTC CCGTCCTTCG GTAGTGTCAC TACTTAGAGG 000320
000321 CAGCTGTGAG GAGCTGTGAT TAATCGTGGA ATGTGCTGAT GTGCCCACTA AAGATGCCTG GTAAGCAGTG GCTCCTCTAA 000400
000401 CAAGTGGGCA GCTTGGAACT GGGAACGAGA GAGCCACCGA AACAGAATGA GGGAGACAAA GAAGTGGGCA TCACCCTTAA 000480
000481 CTCCACAAGG GCTTCCCAAG GGCGCTGTAC CGTACGCAGG CCCAGGACGA ACTTTATTTC TCGCCCCAGC ATCGCTGTCC 000560
000561 TTGTCGGTGA GACCCTGGCT TTAGGGCAGA CAGGACCACG TTTCATAAGT TCATGCTGTC CCAGCAGAGG AATAACGCCA 000640
000641 GAAAGTGTTC CAGTACAACC AGAGAAAGAG AGTCCATGAG AAATCTGCCC TTGTGAAGTT GGAATCCCCT CAACCTCACC 000720
000721 CCGCTGACTT GAATGAAGCG ACTGAGACGG GCTATGATGG AGCAGATCCG GTTGCTCGAC CTTCTCCCTT GCACCAACAC 000800
000801 ATGTAGTTAA TAGTTACTGG ACATGCATAT TCAGTGGGTT CCAGGTACCA AACTTGTATT GAATGGTATG TGCCAGACAC 000880
000881 CGTCTTGAGA TCTGGAGAAT AAAAAAATAA AAAAATAAAA ACGAGACATC CAGAGCACAG TA
000081 GGGTCTCCTG CACCTGAGGG TGGGCGGGAG GCGGCCCCGC GGGTTGTGTT GCTGGAAAAA GGGGTCTCGA TCCAGACCCC 000160
000161 AAGAGAGGGT TCTTGGGTCT ACTTCAGGGA AGAATTGGAG GCGAGTCACA GAGCGCAGTG AAGGAAGCAA GTTTATTGGA 000240
000241 ATCTACTCCG TTAGAGAGTG CAAGTCCTCA GACTGCAGGA GGAGGAACTC CCGTCCTTCG GTAGTGTCAC TACTTAGAGG 000320
000321 CAGCTGTGAG GAGCTGTGAT TAATCGTGGA ATGTGCTGAT GTGCCCACTA AAGATGCCTG GTAAGCAGTG GCTCCTCTAA 000400
000401 CAAGTGGGCA GCTTGGAACT GGGAACGAGA GAGCCACCGA AACAGAATGA GGGAGACAAA GAAGTGGGCA TCACCCTTAA 000480
000481 CTCCACAAGG GCTTCCCAAG GGCGCTGTAC CGTACGCAGG CCCAGGACGA ACTTTATTTC TCGCCCCAGC ATCGCTGTCC 000560
000561 TTGTCGGTGA GACCCTGGCT TTAGGGCAGA CAGGACCACG TTTCATAAGT TCATGCTGTC CCAGCAGAGG AATAACGCCA 000640
000641 GAAAGTGTTC CAGTACAACC AGAGAAAGAG AGTCCATGAG AAATCTGCCC TTGTGAAGTT GGAATCCCCT CAACCTCACC 000720
000721 CCGCTGACTT GAATGAAGCG ACTGAGACGG GCTATGATGG AGCAGATCCG GTTGCTCGAC CTTCTCCCTT GCACCAACAC 000800
000801 ATGTAGTTAA TAGTTACTGG ACATGCATAT TCAGTGGGTT CCAGGTACCA AACTTGTATT GAATGGTATG TGCCAGACAC 000880
000881 CGTCTTGAGA TCTGGAGAAT AAAAAAATAA AAAAATAAAA ACGAGACATC CAGAGCACAG TA
