Difference between revisions of "MIR122HG"

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[[File:MIR122HG.jpg|right|thumb|400px|'''Lnc-pri-miR-122 transcripts are capped but not polyadenylated'''<ref name="ref1" />.]]
 
 
==Annotated Information==
 
==Annotated Information==
 
===Name===
 
===Name===
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===locus===
 
===locus===
 
18q21.31
 
18q21.31
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[[File:MIR122HG.jpg|right|thumb|400px|'''Lnc-pri-miR-122 transcripts are capped but not polyadenylated'''<ref name="ref1" />.]]
 +
 
===Characteristic===
 
===Characteristic===
 
Lnc-pri-miR-122 transcripts are capped but not polyadenylated<ref name="ref1" />
 
Lnc-pri-miR-122 transcripts are capped but not polyadenylated<ref name="ref1" />

Revision as of 06:01, 10 August 2019

Annotated Information

Name

MIR122HG

Alias

lnc-pri-miR-122

ID

ENSG00000267391

locus

18q21.31

Lnc-pri-miR-122 transcripts are capped but not polyadenylated[1].

Characteristic

Lnc-pri-miR-122 transcripts are capped but not polyadenylated[1] lnc-pri-miR-122 3' end is generated by Drosha cleavage and not by CPA[1] Pol II transcribing lnc-pri-miR-122 fails to recognize PAS (polyadenylation site) even when Microprocessor cleavage is inhibited.[1]

Expression

Lnc-pri-miR-122 transcripts are capped but not polyadenylated[1]

Labs working on this lncRNA

  • Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.

References

  1. 1.0 1.1 1.2 1.3 1.4 Dhir A, Dhir S, Proudfoot NJ, Jopling CL. Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs. Nat Struct Mol Biol. 2015 Apr;22(4):319-27. doi: 10.1038/nsmb.2982. Epub 2015 Mar 2. PubMed PMID: 25730776; PubMed Central PMCID: PMC4492989.