Difference between revisions of "CARD8-AS1"

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==Annotated Information==
 
==Annotated Information==
[[File:a.png|right|thumb|400px|'''CARD8-AS1 shRNA Lentivirus Suppresses Glioma Cell Proliferation and Migration and Induces Apoptosis In Vitro''' <ref name="ref1" />.]]
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[[File:A.png|right|thumb|400px|'''CARD8-AS1 shRNA Lentivirus Suppresses Glioma Cell Proliferation and Migration and Induces Apoptosis In Vitro''' <ref name="ref1" />.]]
 
===Approved Symbol===
 
===Approved Symbol===
 
CARD8-AS1
 
CARD8-AS1

Revision as of 05:45, 11 August 2019

Annotated Information

CARD8-AS1 shRNA Lentivirus Suppresses Glioma Cell Proliferation and Migration and Induces Apoptosis In Vitro [1].

Approved Symbol

CARD8-AS1

Approved Name

CARD8 antisense RNA 1

Synonyms

LOC100505812

Chromosome

19q13.33

RefSeq ID

NR_040599

Ensembl ID

ENSG00000268001

Disease

Glioma

Sequence

>gi|341926197|ref|NR_040599.1| Homo sapiens CARD8 antisense RNA 1 (CARD8-AS1), long non-coding RNA

000001 ACTTTGTCGT ACTCCTTCCT TGCTGACTAA GAGGAACAGA ACACAGAGCA GCCTGGCGGT GTCCTACCAA CAAGCCTCCG 000080
000081 TTTCTCCTTC CTGTACACTA GGGCTCCTGA AACTCACCTG ATGAAGTCTC CGTCTGTCAC CCAGGCTGGA GTGTAATGGA 000160
000161 GCAATCTCGG CTCACTGCAA CCTCTGCCTC CCAGGTTCAA GCGATTCTCT TGCCTCAGCC TCCCGAGTAG CTGGAATTAT 000240
000241 AGGTGCATGC CACCACGCTC GGCTAATTTT TTGTATTTTT AGTAAAGACG GAGTTTCACC ATGTTGGTCA GGATGGTCTC 000320
000321 CGTCTCTTGA CCTCGAGATC AGCCCGCCTC GGCCTCCCAA AGTGCTGGGA TTACAGGCGT GAGCCACTGT GCCCGGCCTT 000400
000401 GGTTTCTAAA TACTATTTTG AAGTATCTGT GGAGAAATGG TTACTTCGAG GGCTGGGGCA GGAATATATA AGATAACATT 000480
000481 GGAACAAATT CTGACGCCAG AACATGAAGA AATATTTGAA AAAGGATGGG GCATATTGAC TGAACACAGA AGACAAACAT 000560
000561 GCATGACCTC AGCCTAATCG TGAGAAAACA TCAAAGAAAT CCAAATTGAT AAACATTCTG TAAAATAATT GGCCATGCTC 000640
000641 AGCAAAAGTG TCACAATCAC AAAAGACAAG GGAAGAATAA GAAACGGTCA CAGCCTGGAG GAATCTAAGG ACATAACAAC 000720
000721 TGAGTGCAAT GTGAGATCCT CGATTCGATC TTGGAGAAGA AAGAGGACGT TAAGAGAAAT ATTGACAAAA TTCAAATAAG 000800
000801 GTCTGCACAT TAGGTAATGG TAAGATACGT TGACATCAAT TTCCTGGTTG GATACTTGTA TTACATATAC TATTATGTAT 000880
000881 ATAATTATTA TATTACAATT ACATATACAG TTGTATATTA TATATAATAC AATAAATGTA TATATATGAT TATAATACAA 000960
000961 TAAATGTATA TATACAGTTT TATATATAAC AACTATTATA CATATAATAC AATTATATAT ATAGCTAACA TCAGGATAGG 001040
001041 CTGGTTGAGG ATTTATATGA ATCTTTGCTA ATTTTGCATG TTTAAAATTA TTTCAACATA AAAAAATTAT ATGGGTCATG 001120
001121 TAGTTTTTTG TGCAGTTTAA TTCTAGGCAC CATAGTTTCT GTTTTAATGG GTGTATTTTC TTCTTTCAAG GAATTGGGAT 001200
001201 AGTCTGTTGT ATTAAAAACC TATTCATTTT TGTACATTAA GATTCTTCTG GCCAGGCGCA ATGGCTCAAG CCTATAATCC 001280
001281 CAGCACTTGG GAACCTGAGG CAGGCAGATC ACCTGAGGTC AGGAGTTCAA GACCAGCATG TCCAACATGG TGAAACCCCA 001360
001361 TCTCTACTAA AAATACAAAA AAAATTAGCC AGGCATGGTG GCACATGCCT GTAATCCCAG CTACTTGGGA GGCTGAGGAG 001440
001441 GAGACTCACT AGAACTCAGG AAGCAGAGGT TGCAGTGAGC CAAGACTGCG CCACTGCACT CTGGCCTAAG CAACAGAGGG 001520
001521 AGACTCCATC TCAAAAAAAA AAAAAGATTA TTTCTCTAAC TTACTGGTTT ATCTTTTATA GCTTATTTCA GGTGATTTGT 001600
001601 TGTGTTTGTC TATAGAGTAA AATAACATGT CTAATGAGTT ATAATTTAAT GTCCTTCCAT TCAATCACTG TATTTCAAAT 001680
001681 TTATTCCAAT ATTTTGGAAT AAGCTTCCAA TATTTTAACT TAAATAGGGA AGGTCATACT TGGTATTTTC CTGACCTCAG 001760
001761 CTGGAATGCC TTCATAGTGT TCACATGAAC ACATTTGGCC TGAGAGAGAC TTATTATGCC GAGAATGTGT GTAACCCTTT 001840
001841 TTACTTAGGA ATTGTGGGTG GAGTTTTTCC CCCCGCCCAA GAATGATTGT TAATTTCCGT CCATCATTTT CCTTTGATTG 001920
001921 TTCTTCATCT CGAAAACAAA TAATAAAATA ATAAAATAAA TAAAAAAAAA AAAAAAAAAA AAAA

Function

CARD8-AS1 regulates the metastatic potential of glioma cell lines in vitro, which compared with control groups, lower CARD8-AS1 treatment reduce the number of migrations in U251 and A172 cells [1].

Labs working on this lncRNA

  • College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang 150081, China.[1].

References

  1. 1.0 1.1 1.2 Lin X, Jiang T, Bai J, Li J, Wang T, Xiao J, Tian Y, Jin X, Shao T, Xu J, Chen L, Wang L, Li Y. Characterization of Transcriptome Transition Associates Long Noncoding RNAs with Glioma Progression. Mol Ther Nucleic Acids. 2018 Dec 7;13:620-632. doi: 10.1016/j.omtn.2018.10.009. Epub 2018 Oct 24. PubMed PMID: 30472640; PubMed Central PMCID: PMC6251785