Difference between revisions of "ENST00000441383.1"
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===Function=== | ===Function=== | ||
| − | [[File:Observation of the diagnostic value of using GACAT1 as marker.gif|right|thumb|400px'''Observation of the diagnostic value of using GACAT1 as marker'''<ref name="ref1" />]] | + | [[File:Observation of the diagnostic value of using GACAT1 as marker.gif|right|thumb|400px|'''Observation of the diagnostic value of using GACAT1 as marker'''<ref name="ref1" />]] |
''GACAT1'' was lowly expressed in gastric cancer and the expression level of ''GACAT1'', or AC096655.1-002, was associated with lymph node metastasis, distant metastasis, tumor-node-metastasis stage, and differentiation, suggesting that ''GACAT1'' might serve as a potential biological marker for the clinical diagnosis of gastric cancer <ref name="ref1" />. | ''GACAT1'' was lowly expressed in gastric cancer and the expression level of ''GACAT1'', or AC096655.1-002, was associated with lymph node metastasis, distant metastasis, tumor-node-metastasis stage, and differentiation, suggesting that ''GACAT1'' might serve as a potential biological marker for the clinical diagnosis of gastric cancer <ref name="ref1" />. | ||
Revision as of 08:39, 5 April 2015
GACAT1,gastric cancer associated transcript 1, might serve as a potential biological marker for the clinical diagnosis of gastric cancer.
Contents
Annotated Information
Transcriptomic Nomeclature
GACAT1: gastric cancer associated transcript 1 (HGNC nomenclature)
AC096655.1-002, LINC00876, "long intergenic non-protein coding RNA 876" [1]
Function
GACAT1 was lowly expressed in gastric cancer and the expression level of GACAT1, or AC096655.1-002, was associated with lymph node metastasis, distant metastasis, tumor-node-metastasis stage, and differentiation, suggesting that GACAT1 might serve as a potential biological marker for the clinical diagnosis of gastric cancer [1].
Diseases
Gastric cancer [1]
Expression
GACAT1 has been found significantly downregulated in gastric cancer tissues compared with paired-adjacent non-tumorous tissues. Its expression level was significantly correlated with lymph node metastasis, distant metastasis, TNM stages, and differentiation [1].
Labs working on this lncRNA
Ningbo Yinzhou People's Hospital and the Affiliated Hospital, Ningbo University School of Medicine, Ningbo, 315040, China [1].
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Sun W, Wu Y, Yu X, Liu Y, Song H, Xia T, et al. Decreased expression of long noncoding RNA AC096655.1-002 in gastric cancer and its clinical significance[J]. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2013,34(5):2697-701.
Basic Information
| Transcript ID |
ENST00000441383.1 |
| Source |
Gencode19 |
| Same with |
lnc-RGPD4-1:1,NONHSAT073072,GACAT1,AC096655.1-002, LINC00876, "long intergenic non-protein coding RNA 876" |
| Classification |
intergenic |
| Length |
540 nt |
| Genomic location |
chr2+:108370568..108438585 |
| Exon number |
5 |
| Exons |
108370568..108370726,108371938..108372056,108427136..108427196,108436318..108436440,108438508..108438585 |
| Genome context |
|
| Sequence |
000001 GCGTTTACAA TCCTTTAGCT AGACAGAAAA GTTATCCAAG TCCCCACTCG AACCAGAAAG TCCAGCTGGC TTCACCTCTC 000080
000081 AATAGCCTGC CCATCAGCTG TTCTGTTGCC CTGTAGCCTG CTCCAGATTA TCAGTGAAAT CACCGCAGCC AGAGACCCTT 000160 000161 TCTAGAGTCC AGAAACCTGG TCTGCTTCTC TGGGCTAAGC CTCCTTCTGA AGACACCGGA GGAAAATCCC TAGCTTTGGC 000240 000241 TTTTCCAGCG TCAAGAGCAG CCTTGCATTC CTGTTCCGGA GCAGAATTAG AACAATTTGA TTCTGAATAC ATTTAAGAAT 000320 000321 TAAAAAAAAA CAAAATAATG TCAGGGACAT TTTCTCTTTG TTTCAGTCCT GAGTCCCAAG TCTAGGCCAT GCAGACACAG 000400 000401 AGAAGACACT ATTTTTAAAT GAGGTATTAA ATGAAATGAG TGTGCAAGCA CTTGGCAATC TGATACCTGC TTACCCAGAA 000480 000481 GCTTGTTCTG ACAGCCTTCT CATTTGAAAT CCCAGGAAAT ATAGATAATT CACTCTGATT |
