Difference between revisions of "ENST00000553157.1"

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===Function===
 
===Function===
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KDM5B-AS1 expression appears to stimulate KLHL12 gene expression (in HeLa cells). A gene located ~80kb from KDM5B-AS1 on the opposite strand.
 
 
With the depletion of ncRNA-a2, the KLHL12, a gene known for its negative regulation of the Wnt-beta catenin pathway, displayed a significant reduction <ref name="ref1" />.
 
With the depletion of ncRNA-a2, the KLHL12, a gene known for its negative regulation of the Wnt-beta catenin pathway, displayed a significant reduction <ref name="ref1" />.
 +
 
===Expression===
 
===Expression===
 
Expressed in HeLa, K562 and GM12878 cells, plus a number of human tissues.
 
Expressed in HeLa, K562 and GM12878 cells, plus a number of human tissues.

Revision as of 07:39, 24 June 2016

PCAT6

Annotated Information

Name

PCAT6: prostate cancer associated transcript 6 (non-protein coding) ncRNA-a2, PCAN-R1, KDM5BAS1, onco-lncRNA-96

Characteristics

Function

With the depletion of ncRNA-a2, the KLHL12, a gene known for its negative regulation of the Wnt-beta catenin pathway, displayed a significant reduction [1].

Expression

Expressed in HeLa, K562 and GM12878 cells, plus a number of human tissues.

Conservation

Please input conservation information here.

Misc

Please input misc information here.

Transcriptomic Nomeclature

Please input transcriptomic nomeclature information here.

Regulation

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Allelic Information and Variation

Please input allelic information and variation information here.

Evolution

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You can also add sub-section(s) at will.

Labs working on this lncRNA

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References

Annotation originally sourced from lncRNAdb. <references> [1]

Basic Information

Transcript ID

ENST00000553157.1

Source

Gencode19

Same with

lnc-RP11-480I12.4.1-1:2

Classification

intergenic

Length

551 nt

Genomic location

chr1+:202780082..202781284

Exon number

2

Exons

202780082..202780498,202781151..202781284

Genome context

Sequence
000001 AGAGGCCGGA CCTGGGCAAC CCCAGCCTGG AGGTGCCGGG GCCGGAGCTC CCAGAGGGCT GGGTGCGAGG CCTAGGCGGG 000080
000081 GTCAGGTTCG GGTTCCTAGG CCATAGCGGA GCTGCAGCCC AGGCGGCCGG AGCGGAACCC AGCCCCGCTC CGAGTGCCAC 000160
000161 GTCTCCAGGA ACCCCCTCCT TACTCTTGGA CAACACTCCG CCCCCGCCCG GGCCTCCGTC CCCCAAACCG CCCTCATTTG 000240
000241 TGCAGCGCCA GATCCTTCGG ACACATCCCT AGGTGTCTCC ATCCTCATTC GGTCCATCCA ACTCCCAGAC CTCACGTCAA 000320
000321 CCGGCTGCAC CCCACTTTCC AGCCTGCGCC CCAGATCTGC AGCCTTCGCC CCTAGATACA CCCGCCTGGT GATGAGGCGC 000400
000401 TCCTCGCGTT CCTTCCGGCA CGTGGCACAC GCTCCACAAA TATTTGTTGA AAGGGAGGGT AAATGGCCTT GAGTTTCTGT 000480
000481 GGCTACCATT GGCTGAGGAT GGAGCTTTGG GCTGGACAAA GAAGAATCTG GTTGACCACA TGAAGCAGGA A
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  1. ↑ 1.0 1.1 Orom UA, Derrien T, Beringer M, Gumireddy K, Gardini A, Bussotti G, et al. Long noncoding RNAs with enhancer-like function in human cells[J]. Cell. 2010,143(1):46-58.
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