Difference between revisions of "LINC01684"
Guangyu Wang (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== LINC01684 ===Approved Name=== long intergenic non-protein coding RNA 1684 ===Previous Symbols=== _ ===Synonyms=== lnc-JAM2-6 ==...") |
Jiabao Cao (talk | contribs) |
||
| Line 1: | Line 1: | ||
| + | |||
==Annotated Information== | ==Annotated Information== | ||
| − | === | + | ===Name=== |
| − | LINC01684 | + | LINC01684:long intergenic non-protein coding RNA 1684 |
| − | + | ||
| − | long intergenic non-protein coding RNA 1684 | + | lnc-JAM2-6<ref name="ref1" /> |
| − | = | + | |
| − | + | ===Function=== | |
| − | === | + | rs2829145 A/G located in a lncRNA (lnc-JAM2-6) is associated with nonalcoholic fatty liver disease (NAFLD) and the disease severity. Prediction of regulatory elements in lnc-JAM2-6 showes potential sequence-specific binding motifs of oncogenes MAFK and JUND, and the transcription factor CEBPB that is involved in inflammatory response.<ref name="ref1" /> |
| − | lnc-JAM2-6 | + | ===Diseases=== |
| − | === | + | Nonalcoholic fatty liver disease<ref name="ref1" /> |
| − | + | ===Sequence=== | |
| − | === | + | >NR_135519.1 Homo sapiens long intergenic non-protein coding RNA 1684 (LINC01684), transcript variant 1, long non-coding RNA |
| − | + | <dnaseq>AAGTGACTGTAGGTTTAGATGAATGGAAAATGAACTTGCCAGTTCACAGCTATGTCCTTCCCAATTTAGG | |
| − | == | + | AGGTTAAGGGCAGGAAAAACATGAGAAACTCTTTTGAGAAGCTGCACAAGCTGACATGGAGGATCAAGGA |
| − | + | TTTCAAAAGCTTTGAATATAAAGAGGTCTACCTTAAATCAGTAAGGTCTGTGGCTGTCCAGATGCACATC | |
| − | == | + | ATAATCGGCACAGAACTCTACCATTTGGTCAAAACCAAAAACTAACTGGGACGCCTAAGACTGTAACAGA |
| − | + | CCCCTGGAGACTTCCCACTGGACTCCCCTGAGGCAGATATTTTGCAAAAGAAAACTTCCCGCCATGAGAT | |
| − | + | CTTTTCCCACATTCCCTCTTGGCAACTTAACCAGAAGATAAGGTTAAGTTCATTTCCACGGCCTTTAGAA | |
| − | + | CCTCTGGACCTTATACATGAGAAAAGACATCATTCATGGTTGGAGTCACTGGACCTGGTTAATATGTACC | |
| + | AAAAGGAAACAGAAAAAGCAGTTCTGGTGGCTACATCTTGCAAGTACTAGACCAGAATATAAAGCTGGAT | ||
| + | GAGAGAGACTTTGATGATATGAAGTACTAGGGTTTAAAGGGAACACCGAACTCAGTGGATTGCAAGAGCA | ||
| + | TCTGACATCAGCCCTACTGTGCTTTAGGCATGGCTCTTGGAAATATGACAGACCACAGTACATAGTGTGA | ||
| + | AGTTTCTAGACCTGCCCTGATACAGTGTTGTGGAACCAATATAAAGACTGAGTCACTGGACAAGCTAGAG | ||
| + | TGACTGTGTACTTCAGGATTAACAAAAACATTAGTTTCACTAAGTTTATAAAGATTGAAATTTTTACAGG | ||
| + | CTTAACAGTGGCTGTTGTCTATAGGCCAAGAAGGATTAGCAAGTAATGCTCTTATGAAACAAATGTTGAA | ||
| + | GATGATATACAATTCTAGAAGAGCAAAGGAAAGGTGGTAGCATGTAATCAGTACAGAGAGATAAGGACCA | ||
| + | ACATAATTTCCATGCCAGTTATCAGCAACTCAACAGCTGAGGAACTCTATTATGTAGGAATCTAAGATCA | ||
| + | TGGATGAGCTATCATCACAGTTTTTAGGGGAACTATAGAAAGGCTTCCAATAAGGATTTTTGTACATGTA | ||
| + | CATATATATTCAGAAAGCAGCTAATGTGGAGAAGCAGAAGGTCGATGTCAGCCACTCCAGTGGAAATTTC | ||
| + | AATCACTCATCTACTTTCCAAGCTTGAGCCAACTTTCAGACTGAGAGTCCAATAATTAAAGCAGAAGCTC | ||
| + | TGTTTTTCTGAGAAATGACCTGATGGCAGAGCAAATATATACTGTAAAGATAATTCTCTTCCTCTACTCA | ||
| + | AAGTGTCTGTAGCCGCAGGTACATATGGAAAAGGGAGCACCCACATTTTTTGATATAGTGTGTGAATTGA | ||
| + | AGGAAAGTCAACTTTTACCATAGCCTCCCTTCAAGAGTGGGTACATATGAAAATCAGGTAATAAATTTAG | ||
| + | TTTAACCACGAATTCATTTCACAATGGGTCCAATGAGTCCATATATGCACAATAAAACTTTATTTCCTGA | ||
| + | ATTCATAATTTAGATATACATACATAGTAACTGGCAGAACACTCACTCTAGTTCCTTGAAATGTGAATGA | ||
| + | ATAATAATTGTCATAGGAAAGGTCAAGGAAAAGACTGAAAAATGTCTTTATACCACAGCCAAGAGACTTC | ||
| + | ATAAAGCAATATTGCCTTCCAGATACAATAGAAGAGATCAGTGCCATTTTTAAAAACCTAAAAAGTTGCA | ||
| + | GAGGCAGTTTCTACTGTATTCTCATTTCAGTCACTTGTGTGGCCACACAAAAATCAAATACATGATGGCA | ||
| + | GATTGCAGTGAACTCTAGGACACATACCCAAATGGTAGACATACAAAGCTGTTCTGACAAGTGTGATATT | ||
| + | ACTGGAATGGGTAGACTTGGGTATGTGATACGTGTTAATTCTTATTTTTAGTTGCAGAATTATAATTAGA | ||
| + | CACTTTTTTATAAATTTAAGATTTTGGTTAAAAATAATATATTTGCTTAAACATAAAACACAGTATGTAT | ||
| + | TTTTTTATTGCTACAGGTGACGATGTTTCTCCAGTTTATAGTGATCAAATTTTGTTATCCATTGAGTTCT | ||
| + | AGGAAAGTCTTGAATTTTAATGTTTTTAGACAGAAAGTTTCAAAGGCATCTTTATTGTCAATAAGCTCTT | ||
| + | CAGCTTGGATAAAAGGTAAAAACTAATAAAGGATTCCATTTACATTTAAAAAAAAAAAAAAAAAAA</dnaseq> | ||
| + | ==Labs working on this lncRNA== | ||
| + | *Department of Clinical and Molecular Hepatology, Institute of Medical Research A Lanari-IDIM, University of Buenos Aires - National Scientific and Technical Research Council (CONICET), Ciudad Autónoma de Buenos Aires, Argentina. | ||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> | ||
| + | Sookoian S, Rohr C, Salatino A, Dopazo H, Fernandez Gianotti T, Castaño GO, | ||
| + | Pirola CJ. Genetic variation in long noncoding RNAs and the risk of nonalcoholic | ||
| + | fatty liver disease. Oncotarget. 2017 Apr 4;8(14):22917-22926. | ||
| + | </ref> | ||
| + | </references> | ||
Revision as of 08:20, 28 August 2017
Contents
Annotated Information
Name
LINC01684:long intergenic non-protein coding RNA 1684
lnc-JAM2-6[1]
Function
rs2829145 A/G located in a lncRNA (lnc-JAM2-6) is associated with nonalcoholic fatty liver disease (NAFLD) and the disease severity. Prediction of regulatory elements in lnc-JAM2-6 showes potential sequence-specific binding motifs of oncogenes MAFK and JUND, and the transcription factor CEBPB that is involved in inflammatory response.[1]
Diseases
Nonalcoholic fatty liver disease[1]
Sequence
>NR_135519.1 Homo sapiens long intergenic non-protein coding RNA 1684 (LINC01684), transcript variant 1, long non-coding RNA
000001 AAGTGACTGT AGGTTTAGAT GAATGGAAAA TGAACTTGCC AGTTCACAGC TATGTCCTTC CCAATTTAGG AGGTTAAGGG 000080
000081 CAGGAAAAAC ATGAGAAACT CTTTTGAGAA GCTGCACAAG CTGACATGGA GGATCAAGGA TTTCAAAAGC TTTGAATATA 000160
000161 AAGAGGTCTA CCTTAAATCA GTAAGGTCTG TGGCTGTCCA GATGCACATC ATAATCGGCA CAGAACTCTA CCATTTGGTC 000240
000241 AAAACCAAAA ACTAACTGGG ACGCCTAAGA CTGTAACAGA CCCCTGGAGA CTTCCCACTG GACTCCCCTG AGGCAGATAT 000320
000321 TTTGCAAAAG AAAACTTCCC GCCATGAGAT CTTTTCCCAC ATTCCCTCTT GGCAACTTAA CCAGAAGATA AGGTTAAGTT 000400
000401 CATTTCCACG GCCTTTAGAA CCTCTGGACC TTATACATGA GAAAAGACAT CATTCATGGT TGGAGTCACT GGACCTGGTT 000480
000481 AATATGTACC AAAAGGAAAC AGAAAAAGCA GTTCTGGTGG CTACATCTTG CAAGTACTAG ACCAGAATAT AAAGCTGGAT 000560
000561 GAGAGAGACT TTGATGATAT GAAGTACTAG GGTTTAAAGG GAACACCGAA CTCAGTGGAT TGCAAGAGCA TCTGACATCA 000640
000641 GCCCTACTGT GCTTTAGGCA TGGCTCTTGG AAATATGACA GACCACAGTA CATAGTGTGA AGTTTCTAGA CCTGCCCTGA 000720
000721 TACAGTGTTG TGGAACCAAT ATAAAGACTG AGTCACTGGA CAAGCTAGAG TGACTGTGTA CTTCAGGATT AACAAAAACA 000800
000801 TTAGTTTCAC TAAGTTTATA AAGATTGAAA TTTTTACAGG CTTAACAGTG GCTGTTGTCT ATAGGCCAAG AAGGATTAGC 000880
000881 AAGTAATGCT CTTATGAAAC AAATGTTGAA GATGATATAC AATTCTAGAA GAGCAAAGGA AAGGTGGTAG CATGTAATCA 000960
000961 GTACAGAGAG ATAAGGACCA ACATAATTTC CATGCCAGTT ATCAGCAACT CAACAGCTGA GGAACTCTAT TATGTAGGAA 001040
001041 TCTAAGATCA TGGATGAGCT ATCATCACAG TTTTTAGGGG AACTATAGAA AGGCTTCCAA TAAGGATTTT TGTACATGTA 001120
001121 CATATATATT CAGAAAGCAG CTAATGTGGA GAAGCAGAAG GTCGATGTCA GCCACTCCAG TGGAAATTTC AATCACTCAT 001200
001201 CTACTTTCCA AGCTTGAGCC AACTTTCAGA CTGAGAGTCC AATAATTAAA GCAGAAGCTC TGTTTTTCTG AGAAATGACC 001280
001281 TGATGGCAGA GCAAATATAT ACTGTAAAGA TAATTCTCTT CCTCTACTCA AAGTGTCTGT AGCCGCAGGT ACATATGGAA 001360
001361 AAGGGAGCAC CCACATTTTT TGATATAGTG TGTGAATTGA AGGAAAGTCA ACTTTTACCA TAGCCTCCCT TCAAGAGTGG 001440
001441 GTACATATGA AAATCAGGTA ATAAATTTAG TTTAACCACG AATTCATTTC ACAATGGGTC CAATGAGTCC ATATATGCAC 001520
001521 AATAAAACTT TATTTCCTGA ATTCATAATT TAGATATACA TACATAGTAA CTGGCAGAAC ACTCACTCTA GTTCCTTGAA 001600
001601 ATGTGAATGA ATAATAATTG TCATAGGAAA GGTCAAGGAA AAGACTGAAA AATGTCTTTA TACCACAGCC AAGAGACTTC 001680
001681 ATAAAGCAAT ATTGCCTTCC AGATACAATA GAAGAGATCA GTGCCATTTT TAAAAACCTA AAAAGTTGCA GAGGCAGTTT 001760
001761 CTACTGTATT CTCATTTCAG TCACTTGTGT GGCCACAC<
000081 CAGGAAAAAC ATGAGAAACT CTTTTGAGAA GCTGCACAAG CTGACATGGA GGATCAAGGA TTTCAAAAGC TTTGAATATA 000160
000161 AAGAGGTCTA CCTTAAATCA GTAAGGTCTG TGGCTGTCCA GATGCACATC ATAATCGGCA CAGAACTCTA CCATTTGGTC 000240
000241 AAAACCAAAA ACTAACTGGG ACGCCTAAGA CTGTAACAGA CCCCTGGAGA CTTCCCACTG GACTCCCCTG AGGCAGATAT 000320
000321 TTTGCAAAAG AAAACTTCCC GCCATGAGAT CTTTTCCCAC ATTCCCTCTT GGCAACTTAA CCAGAAGATA AGGTTAAGTT 000400
000401 CATTTCCACG GCCTTTAGAA CCTCTGGACC TTATACATGA GAAAAGACAT CATTCATGGT TGGAGTCACT GGACCTGGTT 000480
000481 AATATGTACC AAAAGGAAAC AGAAAAAGCA GTTCTGGTGG CTACATCTTG CAAGTACTAG ACCAGAATAT AAAGCTGGAT 000560
000561 GAGAGAGACT TTGATGATAT GAAGTACTAG GGTTTAAAGG GAACACCGAA CTCAGTGGAT TGCAAGAGCA TCTGACATCA 000640
000641 GCCCTACTGT GCTTTAGGCA TGGCTCTTGG AAATATGACA GACCACAGTA CATAGTGTGA AGTTTCTAGA CCTGCCCTGA 000720
000721 TACAGTGTTG TGGAACCAAT ATAAAGACTG AGTCACTGGA CAAGCTAGAG TGACTGTGTA CTTCAGGATT AACAAAAACA 000800
000801 TTAGTTTCAC TAAGTTTATA AAGATTGAAA TTTTTACAGG CTTAACAGTG GCTGTTGTCT ATAGGCCAAG AAGGATTAGC 000880
000881 AAGTAATGCT CTTATGAAAC AAATGTTGAA GATGATATAC AATTCTAGAA GAGCAAAGGA AAGGTGGTAG CATGTAATCA 000960
000961 GTACAGAGAG ATAAGGACCA ACATAATTTC CATGCCAGTT ATCAGCAACT CAACAGCTGA GGAACTCTAT TATGTAGGAA 001040
001041 TCTAAGATCA TGGATGAGCT ATCATCACAG TTTTTAGGGG AACTATAGAA AGGCTTCCAA TAAGGATTTT TGTACATGTA 001120
001121 CATATATATT CAGAAAGCAG CTAATGTGGA GAAGCAGAAG GTCGATGTCA GCCACTCCAG TGGAAATTTC AATCACTCAT 001200
001201 CTACTTTCCA AGCTTGAGCC AACTTTCAGA CTGAGAGTCC AATAATTAAA GCAGAAGCTC TGTTTTTCTG AGAAATGACC 001280
001281 TGATGGCAGA GCAAATATAT ACTGTAAAGA TAATTCTCTT CCTCTACTCA AAGTGTCTGT AGCCGCAGGT ACATATGGAA 001360
001361 AAGGGAGCAC CCACATTTTT TGATATAGTG TGTGAATTGA AGGAAAGTCA ACTTTTACCA TAGCCTCCCT TCAAGAGTGG 001440
001441 GTACATATGA AAATCAGGTA ATAAATTTAG TTTAACCACG AATTCATTTC ACAATGGGTC CAATGAGTCC ATATATGCAC 001520
001521 AATAAAACTT TATTTCCTGA ATTCATAATT TAGATATACA TACATAGTAA CTGGCAGAAC ACTCACTCTA GTTCCTTGAA 001600
001601 ATGTGAATGA ATAATAATTG TCATAGGAAA GGTCAAGGAA AAGACTGAAA AATGTCTTTA TACCACAGCC AAGAGACTTC 001680
001681 ATAAAGCAAT ATTGCCTTCC AGATACAATA GAAGAGATCA GTGCCATTTT TAAAAACCTA AAAAGTTGCA GAGGCAGTTT 001760
001761 CTACTGTATT CTCATTTCAG TCACTTGTGT GGCCACAC<