Difference between revisions of "LINC02231"
Guangyu Wang (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== LINC02231 ===Approved Name=== long intergenic non-protein coding RNA 2231 ===Previous Symbols=== _ ===Synonyms=== RP11-766N7.4 ...") |
Jiabao Cao (talk | contribs) |
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==Annotated Information== | ==Annotated Information== | ||
| − | === | + | ===Name=== |
| − | LINC02231 | + | LINC02231:long intergenic non-protein coding RNA 2231 |
| − | + | ||
| − | long intergenic non-protein coding RNA 2231 | + | RP11-766N7.4<ref name="ref1" /> |
| − | === | + | |
| − | + | ===Characteristics=== | |
| − | === | + | Long noncoding RNA RP11-766N7.4, originally discovered by Ensembl GenomeBioinformatics, is located on the reversed strand in 12q14.3 region with a length of 447 bps.<ref name="ref1" /> |
| − | RP11-766N7.4 | + | |
| − | + | ===Function=== | |
| − | + | The long noncoding RNA RP11-766N7.4 expression is negatively correlated with lymph node metastasis(P=0.000) and tumor stage (P=0.034). | |
| − | === | + | Long noncoding RNA RP11-766N7.4 knockdown promotes cellular migration and invasion via inducing EMT process, and overexpression of long noncoding RNA RP11-766N7.4 inhibites cellular migration and invasion by suppressing EMT process.<ref name="ref1" /> |
| − | + | ||
| − | === | + | |
| − | + | ===Diseases=== | |
| − | == | + | Esophageal squamous cell carcinoma<ref name="ref1" /> |
| − | + | ||
| − | == | + | ===Expression=== |
| − | + | RT-qPCR results show that the long noncoding RNA RP11-766N7.4 expression level is remarkably lower in 50 Esophageal squamous cell carcinoma(ESCC) tissue samples compared with the corresponding adjacent tissues.<ref name="ref1" /> | |
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | * Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China. | ||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1"> | ||
| + | Yao GL, Pan CF, Xu H, Wei K, Liu B, Zhai R, Chen YJ. Long noncoding RNA | ||
| + | RP11-766N7.4 functions as a tumor suppressor by regulating epithelial-mesenchymal | ||
| + | transition in esophageal squamous cell carcinoma. Biomed Pharmacother. 2017 | ||
| + | Apr;88:778-785. | ||
| + | </ref> | ||
| + | </references> | ||
Revision as of 09:22, 29 August 2017
Contents
Annotated Information
Name
LINC02231:long intergenic non-protein coding RNA 2231
RP11-766N7.4[1]
Characteristics
Long noncoding RNA RP11-766N7.4, originally discovered by Ensembl GenomeBioinformatics, is located on the reversed strand in 12q14.3 region with a length of 447 bps.[1]
Function
The long noncoding RNA RP11-766N7.4 expression is negatively correlated with lymph node metastasis(P=0.000) and tumor stage (P=0.034). Long noncoding RNA RP11-766N7.4 knockdown promotes cellular migration and invasion via inducing EMT process, and overexpression of long noncoding RNA RP11-766N7.4 inhibites cellular migration and invasion by suppressing EMT process.[1]
Diseases
Esophageal squamous cell carcinoma[1]
Expression
RT-qPCR results show that the long noncoding RNA RP11-766N7.4 expression level is remarkably lower in 50 Esophageal squamous cell carcinoma(ESCC) tissue samples compared with the corresponding adjacent tissues.[1]
Labs working on this lncRNA
- Department of Thoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, PR China.
