Difference between revisions of "KRT7-AS"
| Line 6: | Line 6: | ||
===RefSeq=== | ===RefSeq=== | ||
NG_012296 | NG_012296 | ||
| + | [[File:Expression pattern of KRT7-AS and KRT7 mRNAs in cell lines and tissues.jpg|right|thumb|280px|'''Expression pattern of KRT7-AS and KRT7 mRNAs in cell lines and tissues.'''<ref name="ref1"/>]] | ||
| + | [[File:Regulatory function of KRT7-AS overexpression to KRT7.jpg|right|thumb|280px|'''Regulatory function of KRT7-AS overexpression to KRT7.'''<ref name="ref1"/>]] | ||
| + | |||
===Characteristics=== | ===Characteristics=== | ||
| − | KRT7-AS shares a 213-nucleotide-long region with the seventh exon of KRT7.<ref name="ref1"/> | + | KRT7-AS is localized to the nucleus and it shares a 213-nucleotide-long region with the seventh exon of KRT7.<ref name="ref1"/> |
| − | |||
===Expression=== | ===Expression=== | ||
| − | + | In the same samples, KRT7 mRNA levels are much higher than KRT7-AS levels. In MKN28 and KATOIII cells, KRT7 mRNA is 61 and 41 fold higher than KRT7-AS (P<0.01). | |
===pubmed IDs=== | ===pubmed IDs=== | ||
26876208 | 26876208 | ||
| Line 22: | Line 24: | ||
==References== | ==References== | ||
<references> | <references> | ||
| − | <ref name="ref1"> | + | <ref name="ref1">Huang, B., et al., Long non-coding antisense RNA KRT7-AS is activated in gastric cancers and supports cancer cell progression by increasing KRT7 expression. Oncogene, 2016. 35(37): p. 4927-36. |
</ref>(1) | </ref>(1) | ||
</references> | </references> | ||
Revision as of 08:55, 15 October 2017
Contents
Annotated Information
Approved Symbol
KRT7-AS (KRT7 antisense RNA 1)
Chromosome
12q13.13
RefSeq
NG_012296
Expression pattern of KRT7-AS and KRT7 mRNAs in cell lines and tissues.[1]
Regulatory function of KRT7-AS overexpression to KRT7.[1]
Characteristics
KRT7-AS is localized to the nucleus and it shares a 213-nucleotide-long region with the seventh exon of KRT7.[1]
Expression
In the same samples, KRT7 mRNA levels are much higher than KRT7-AS levels. In MKN28 and KATOIII cells, KRT7 mRNA is 61 and 41 fold higher than KRT7-AS (P<0.01).
pubmed IDs
26876208
Disease
gastric cancer
Labs working on this lncRNA
- Department of Gastroenterology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
- Division of Gastroenterology, Departments of Medicine and Oncology and Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
