Difference between revisions of "LINC01844"
| Line 6: | Line 6: | ||
===Synonyms=== | ===Synonyms=== | ||
LOC101926975 | LOC101926975 | ||
| + | [[File:Expression of LOC101926975 in HSCR.png|right|thumb|400px|'''LOC101926975 is significantly downregulated in HSCR tissues compared control samples'''.<ref name="ref1" />]] | ||
| + | [[File:Function of LOC101926975 in vitro.ipg|right|thumb|400px|'''(A) LOC101926975 was effectively knocked down in SK-N-BE(2) cells. Downregulation of LOC101926975 suppressed cell proliferation (B)and caused cell cycle arrest (C)without impact on cell apoptosis (D)or cell migration.'''.<ref name="ref1" />]] | ||
===Chromosome=== | ===Chromosome=== | ||
5q31.3 | 5q31.3 | ||
| Line 14: | Line 16: | ||
===Characteristics=== | ===Characteristics=== | ||
LOC101926975 locates on chromosome 5 (142745600-142760993) and it is near the gene FGF1. <ref name="ref1" /> | LOC101926975 locates on chromosome 5 (142745600-142760993) and it is near the gene FGF1. <ref name="ref1" /> | ||
| − | |||
===Expression=== | ===Expression=== | ||
Compared with the control tissues, the expression of LOC101926975 is down-regulated in hirschsprung disease (HSCR) tissues. <ref name="ref1" /> | Compared with the control tissues, the expression of LOC101926975 is down-regulated in hirschsprung disease (HSCR) tissues. <ref name="ref1" /> | ||
| Line 27: | Line 28: | ||
| | 5'-GCAGGGGAAAATACCAGGGAA- 3'<ref name="ref1" /> | | | 5'-GCAGGGGAAAATACCAGGGAA- 3'<ref name="ref1" /> | ||
|} | |} | ||
| − | + | ===Function=== | |
| + | SiRNA experiment show that LOC101926975 knockdown inhibits cell proliferation and blocks the G0/G1 to S phase transition. | ||
===pubmed IDs=== | ===pubmed IDs=== | ||
27076786 | 27076786 | ||
Revision as of 13:21, 22 October 2017
Contents
Annotated Information
Approved Symbol
LINC01844
Approved Name
long intergenic non-protein coding RNA 1844
Synonyms
LOC101926975
LOC101926975 is significantly downregulated in HSCR tissues compared control samples.[1]
File:Function of LOC101926975 in vitro.ipg
(A) LOC101926975 was effectively knocked down in SK-N-BE(2) cells. Downregulation of LOC101926975 suppressed cell proliferation (B)and caused cell cycle arrest (C)without impact on cell apoptosis (D)or cell migration..[1]
Chromosome
5q31.3
RefSeq ID
NR_110558
RefSeq(supplied by NCBI)
NR_110558
Characteristics
LOC101926975 locates on chromosome 5 (142745600-142760993) and it is near the gene FGF1. [1]
Expression
Compared with the control tissues, the expression of LOC101926975 is down-regulated in hirschsprung disease (HSCR) tissues. [1]
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| qRT-PCR | 5'-AACCCAGTGTTCAAAACCCCA- 3' | 5'-GCAGGGGAAAATACCAGGGAA- 3'[1] |
Function
SiRNA experiment show that LOC101926975 knockdown inhibits cell proliferation and blocks the G0/G1 to S phase transition.
