Difference between revisions of "PPP1R12A-AS1"

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12q21.31
 
12q21.31
 
===Characteristics===
 
===Characteristics===
PPP1R12A-AS1 overlaps with the 5'UTR and first coding exon of the PPP1R12A mRNA.<ref name="ref1" />
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PPP1R12A-AS1 is an antisense lncRNA to the human protein phosphatase 1 regulatory subunit 12A and overlaps with the 5'UTR and first coding exon of the PPP1R12A mRNA.<ref name="ref1" />
  
 
===Expression===
 
===Expression===

Revision as of 12:10, 28 October 2017

Annotated Information

Approved Symbol

PPP1R12A-AS1 (PPP1R12A antisense RNA 1)1

Synonyms

R12A-AS1

Expression and functional characterization of R12A-AS1[1]

Chromosome

12q21.31

Characteristics

PPP1R12A-AS1 is an antisense lncRNA to the human protein phosphatase 1 regulatory subunit 12A and overlaps with the 5'UTR and first coding exon of the PPP1R12A mRNA.[1]

Expression

Blood cells and neural tissues express PPP1R12A-AS1 at highest levels.[1]

Function

In human, R12A-AS1 function as SINEUP which can increase the level of recombinant protein.[1]

Labs working on this lncRNA

  • Division of Genomic Technologies, RIKEN Center for Life Science Technologies, RIKEN Yokohama Campus, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045 Japan.
  • Center for RNA Medicine, Department of Clinical Medicine, Aalborg University Campus Copenhagen, Copenhagen 2450 Denmark.
  • Scuola Internazionale Superiore di Studi Avanzati, Area of Neuroscience, Trieste, Italy.
  • Department of Health Sciences, University of Eastern Piedmont, Novara, Italy.
  • Department of Neuroscience and Brain Technologies, Italian Institute of Technology, Genova, Italy。

References

  1. 1.0 1.1 1.2 1.3 Schein, A., et al., Identification of antisense long noncoding RNAs that function as SINEUPs in human cells. Sci Rep, 2016. 6: p. 33605.