Difference between revisions of "LINC01852"
Guangyu Wang (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== LINC01852 ===Approved Name=== long intergenic non-protein coding RNA 1852 ===Previous Symbols=== _ ===Synonyms=== ENST000004342...") |
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==Annotated Information== | ==Annotated Information== | ||
| + | [[File: Effect of ENST00000434223 on cell growth in vivo.png|right|thumb|400px|''' Effect of LINC01852 on cell growth in vivo'''<ref name="ref1" />]] | ||
| + | [[File: Effect of ENST00000434223 on cell invasion.png|right|thumb|400px|''' Effect of LINC01852 on cell invasion'''<ref name="ref1" />]] | ||
| + | |||
===Approved Symbol=== | ===Approved Symbol=== | ||
| − | LINC01852 | + | LINC01852 (long intergenic non-protein coding RNA 1852) |
| − | |||
| − | long intergenic non-protein coding RNA 1852 | ||
| − | |||
| − | |||
===Synonyms=== | ===Synonyms=== | ||
ENST00000434223 | ENST00000434223 | ||
===Chromosome=== | ===Chromosome=== | ||
15q14 | 15q14 | ||
| − | |||
| − | |||
| − | |||
| − | |||
===RefSeq(supplied by NCBI)=== | ===RefSeq(supplied by NCBI)=== | ||
XR_001751481 | XR_001751481 | ||
===pubmed IDs=== | ===pubmed IDs=== | ||
26883250 | 26883250 | ||
| + | ===Characteristics=== | ||
| + | LINC01852 is localized in Human chromosome 15 (38363831–38364884) and has a transcript of about 964 bp.<ref name="ref1" /> | ||
| + | |||
| + | ===Expression=== | ||
| + | The expression level of LINC01852 is significantly downregulated in cancerous tissues compared with paired adjacent normal tissues.<ref name="ref1" /> | ||
| + | LINC01852 overexpression induced a significant increase in the percentage of cells in G0/G1 phase as determined by flow cytometric assay .<ref name="ref1" /> | ||
| + | |||
| + | The primer sequences used in this study were as follows: | ||
| + | {| class='wikitable' style="text-align:center" | ||
| + | |- | ||
| + | ! | Experiment | ||
| + | ! | Forward primer | ||
| + | ! | Reverse primer | ||
| + | |- | ||
| + | | rowspan="1"|qRT-PCR | ||
| + | | | 5'-GCAAGTGTTGAAGGACGACGAT-3′ | ||
| + | | | 5′CAAGGAGGCATACACGGAGTT-3′<ref name="ref1" /> | ||
| + | |} | ||
| + | |||
| + | ===Function=== | ||
| + | Overexpression of LINC01852 inhibits proliferation and migration of NSCLC cells in vitro.<ref name="ref1" /> | ||
| + | |||
| + | ==Labs working on this lncRNA== | ||
| + | * School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China. | ||
| + | * Department of Pathology, the Affiliated Cancer Hospital to Zhengzhou University, Zhengzhou, China. | ||
| + | |||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1">Chai, X., X. Ye, and Y. Song, Long noncoding RNA ENST00000434223 suppressed tumor progression in non-small cell lung cancer. Tumour Biol, 2016. 37(8): p. 10851-60. | ||
| + | </ref>(1) | ||
| + | </references> | ||
Latest revision as of 11:08, 19 November 2017
Contents
Annotated Information
Effect of LINC01852 on cell growth in vivo[1]
Effect of LINC01852 on cell invasion[1]
Approved Symbol
LINC01852 (long intergenic non-protein coding RNA 1852)
Synonyms
ENST00000434223
Chromosome
15q14
RefSeq(supplied by NCBI)
XR_001751481
pubmed IDs
26883250
Characteristics
LINC01852 is localized in Human chromosome 15 (38363831–38364884) and has a transcript of about 964 bp.[1]
Expression
The expression level of LINC01852 is significantly downregulated in cancerous tissues compared with paired adjacent normal tissues.[1] LINC01852 overexpression induced a significant increase in the percentage of cells in G0/G1 phase as determined by flow cytometric assay .[1]
The primer sequences used in this study were as follows:
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| qRT-PCR | 5'-GCAAGTGTTGAAGGACGACGAT-3′ | 5′CAAGGAGGCATACACGGAGTT-3′[1] |
Function
Overexpression of LINC01852 inhibits proliferation and migration of NSCLC cells in vitro.[1]
Labs working on this lncRNA
- School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.
- Department of Pathology, the Affiliated Cancer Hospital to Zhengzhou University, Zhengzhou, China.
