Difference between revisions of "MGAT3-AS1"

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==Annotated Information==
 
==Annotated Information==
 
===Approved Symbol===
 
===Approved Symbol===
MGAT3-AS1
+
MGAT3-AS1 (MGAT3 antisense RNA 1)
===Approved Name===
 
MGAT3 antisense RNA 1
 
===Previous Symbols===
 
_
 
 
===Synonyms===
 
===Synonyms===
 
TapSAKI
 
TapSAKI
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===RefSeq ID===
 
===RefSeq ID===
 
NR_126469
 
NR_126469
===OMIM ID===
 
_
 
 
===Ensembl ID===
 
===Ensembl ID===
 
ENSG00000227188
 
ENSG00000227188
 
===pubmed IDs===
 
===pubmed IDs===
 
25294924
 
25294924
 +
 +
===Characteristics===
 +
TapSAKI is an intronic antisense lncRNA, transcribed from a gene located in the genome on chromosome 22.<ref name="ref1" />
 +
 +
===Expression===
 +
TapSAKI was significantly increased in these patients compared to healthy controls and disease controls.<ref name="ref1" />
 +
 +
===Function===
 +
TapSAKI can predicts the survival of AKI and thus has the biomarker potential of AKI (P �<0.001).<ref name="ref1" />
 +
TapSAKI is specifically enriched in hypoxic renal tubular epithelial cells.<ref name="ref1" />
 +
 +
==Labs working on this lncRNA==
 +
* Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and Department of Medicine/Division of Nephrology and Hypertension, Hannover Medical School, Hannover,<ref name="ref1" /> Germany.
 +
* Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and National Heart and Lung Institute, Imperial College London, London, UK. lorenzen.<ref name="ref1" />
 +
 +
==References==
 +
<references>
 +
<ref name="ref1">
 +
</ref>(1)
 +
</references>
 +
 
===Sequence===
 
===Sequence===
 
>gi|704000385|ref|NR_126469.1| Homo sapiens MGAT3 antisense RNA 1 (MGAT3-AS1), long non-coding RNA
 
>gi|704000385|ref|NR_126469.1| Homo sapiens MGAT3 antisense RNA 1 (MGAT3-AS1), long non-coding RNA
 
<dnaseq>GCTACTGGTGGTCATCGGGGACGCAGATATGTGTGTCTCCATTTTGCAGATGAGGACATGGAGGCCTCAAGAGGTTAAGTGACTTGCTCAGCCACACACAGCTGATGGGAATGAAACAGACGGAAACGGAGACTCCCCAAGCTGACAGGCGGACTACAGATCTGGGGGTTCTGCTCCAGGCTCAACACAAGTGGCCTGGGCGAGGGAGGGCCTGGTAGACCATGACACCCAGCATCGAGGAATTCTGCTTCCCCAGCAGGCTCAGAAGGAAGAAGTCTGCTTCAGGGGCCAGGCCTGGTCAAAGACTCCATCTTCCCTGGATGGCCAGAGTCAAATCCTTGCAAATCCCGTTCACCATGGAGCAGAGACGAGACCTATGTTACCCAGGCTGTATGTGAATTCCTGGACTCAAGCAATCCTCCCATCTCAGCCTCGTGAGTAGTTGGGACAAGTCTCACACCACCATACCCAGCTTAATTTAATTTGAATTTTAATAGC</dnaseq>
 
<dnaseq>GCTACTGGTGGTCATCGGGGACGCAGATATGTGTGTCTCCATTTTGCAGATGAGGACATGGAGGCCTCAAGAGGTTAAGTGACTTGCTCAGCCACACACAGCTGATGGGAATGAAACAGACGGAAACGGAGACTCCCCAAGCTGACAGGCGGACTACAGATCTGGGGGTTCTGCTCCAGGCTCAACACAAGTGGCCTGGGCGAGGGAGGGCCTGGTAGACCATGACACCCAGCATCGAGGAATTCTGCTTCCCCAGCAGGCTCAGAAGGAAGAAGTCTGCTTCAGGGGCCAGGCCTGGTCAAAGACTCCATCTTCCCTGGATGGCCAGAGTCAAATCCTTGCAAATCCCGTTCACCATGGAGCAGAGACGAGACCTATGTTACCCAGGCTGTATGTGAATTCCTGGACTCAAGCAATCCTCCCATCTCAGCCTCGTGAGTAGTTGGGACAAGTCTCACACCACCATACCCAGCTTAATTTAATTTGAATTTTAATAGC</dnaseq>

Revision as of 07:37, 26 November 2017

Annotated Information

Approved Symbol

MGAT3-AS1 (MGAT3 antisense RNA 1)

Synonyms

TapSAKI

Disease

acute kidney injury

Chromosome

22q13.1

RefSeq ID

NR_126469

Ensembl ID

ENSG00000227188

pubmed IDs

25294924

Characteristics

TapSAKI is an intronic antisense lncRNA, transcribed from a gene located in the genome on chromosome 22.[1]

Expression

TapSAKI was significantly increased in these patients compared to healthy controls and disease controls.[1]

Function

TapSAKI can predicts the survival of AKI and thus has the biomarker potential of AKI (P �<0.001).[1] TapSAKI is specifically enriched in hypoxic renal tubular epithelial cells.[1]

Labs working on this lncRNA

  • Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and Department of Medicine/Division of Nephrology and Hypertension, Hannover Medical School, Hannover,[1] Germany.
  • Institute of Molecular and Translational Therapeutic Strategies (IMTTS) and National Heart and Lung Institute, Imperial College London, London, UK. lorenzen.[1]

References

Sequence

>gi|704000385|ref|NR_126469.1| Homo sapiens MGAT3 antisense RNA 1 (MGAT3-AS1), long non-coding RNA

000001 GCTACTGGTG GTCATCGGGG ACGCAGATAT GTGTGTCTCC ATTTTGCAGA TGAGGACATG GAGGCCTCAA GAGGTTAAGT 000080
000081 GACTTGCTCA GCCACACACA GCTGATGGGA ATGAAACAGA CGGAAACGGA GACTCCCCAA GCTGACAGGC GGACTACAGA 000160
000161 TCTGGGGGTT CTGCTCCAGG CTCAACACAA GTGGCCTGGG CGAGGGAGGG CCTGGTAGAC CATGACACCC AGCATCGAGG 000240
000241 AATTCTGCTT CCCCAGCAGG CTCAGAAGGA AGAAGTCTGC TTCAGGGGCC AGGCCTGGTC AAAGACTCCA TCTTCCCTGG 000320
000321 ATGGCCAGAG TCAAATCCTT GCAAATCCCG TTCACCATGG AGCAGAGACG AGACCTATGT TACCCAGGCT GTATGTGAAT 000400
000401 TCCTGGACTC AAGCAATCCT CCCATCTCAG CCTCGTGAGT AGTTGGGACA AGTCTCACAC CACCATACCC AGCTTAATTT 000480
000481 AATTTGAATT TTAATAGC