Difference between revisions of "MAP3K2-DT"

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''MAP3K2-DT'' may contribute to the occurrence of polycystic ovary syndrome (PCOS) and affect oocyte development.
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''MAP3K2-DT'' is a long noncoding RNA that may contribute to the occurrence of polycystic ovary syndrome (PCOS) and affect oocyte development.
  
 
==Annotated Information==
 
==Annotated Information==
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===Expression===
 
===Expression===
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[[File:MAP3K2-DT.jpg|right|thumb|400px|'''The expression levels of the five selected lncRNAs (XLOC_011402, ENST00000454271, ENST00000433673, ENST00000450294, and ENST00000432431) were examined by qRT-PCR in a cohort of CC samples isolated from an additional 30 PCOS and 30 normal patients. ''' <ref name="ref1" />]]
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[[File:MAP3K2-DT.jpg|right|thumb|400px|''The expression levels of the five selected lncRNAs (XLOC_011402, ENST00000454271, ENST00000433673, ENST00000450294, and ENST00000432431) were examined by qRT-PCR in a cohort of CC samples isolated from an additional 30 PCOS and 30 normal patients. '' <ref name="ref1" />]]
 
''MAP3K2-DT'' is upregulated lncRNA in polycystic ovary syndrome (PCOS) <ref name="ref1" />.  
 
''MAP3K2-DT'' is upregulated lncRNA in polycystic ovary syndrome (PCOS) <ref name="ref1" />.  
  

Revision as of 07:06, 27 December 2018

MAP3K2-DT is a long noncoding RNA that may contribute to the occurrence of polycystic ovary syndrome (PCOS) and affect oocyte development.

Annotated Information

Name

MAP3K2-DT: MAP3K2 divergent transcript (HGNC nomenclature), ENST00000433673 [1].

Characteristics

MAP3K2-DT is 3445 bp long non-coding RNA, located on human chromosome 2q14.3.

Function

Please input information here.

Expression

The expression levels of the five selected lncRNAs (XLOC_011402, ENST00000454271, ENST00000433673, ENST00000450294, and ENST00000432431) were examined by qRT-PCR in a cohort of CC samples isolated from an additional 30 PCOS and 30 normal patients. [1]

MAP3K2-DT is upregulated lncRNA in polycystic ovary syndrome (PCOS) [1].

Regulation

Please input information here.

Diseases

  • Polycystic ovary syndrome (PCOS) [1]

Labs working on this lncRNA

  • Reproductive Medicine Centre, Affiliated Hospital of Qingdao Medical University, Yuhuangding Hospital of Yantai, 20 Yuhuangding Road East, Yantai, Shandong 264000 People’s Republic of China.[1]

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Huang X, Hao CF, Bao HC, Wang MM & Dai HG. Aberrant expression of long noncoding RNAs in cumulus cells isolated from PCOS patients[J]. J Assist Reprod Gen. 2016, 33(1):111-121.

Sequence

>gi|100506922|ref|XR_001739702.2| Homo sapiens , MAP3K2 divergent transcript (MAP3K2-DT), long non-coding RNA

000001 GTTCCGTGTG CGCGGCGCAT ACGCACCTGG GTTGTCTCGA GCCTGCGGTA GTGGCCAGAT CCCAGACATC CGAGTAGATC 000080
000081 CCGTGAAAAG CTTCTTCTTG GTTTCTTCGT ACATTCTGGA TCCACCCCTT TCATGCATAT TCCAGACCAC ATTTCCACTG 000160
000161 GAGCAGTTGA AATGAGAGAG ATGGGAATGG GACTCACCCG AACCAGAGGA ATTTTTATTA CAGACCCATT AACAGAGGTG 000240
000241 TCAAAGTCAC AGGAACAAGG ATGTGCACCT CAGAAACACA GAGGCTAGCC TGGCTGAAGC TCAGCTGCAC AGAGTCTGTC 000320
000321 CTGAGAAGCA GAATGCCACT GTCCCCTGGG CCCTCCAGAC TGCCAAGGCT GCTCAGTTTC AGAGAGCAGG CTCCCTGTGG 000400
000401 CCTCACACGC CGGCTGCCAG CTGGGCCAGG TAACTCTGGC CAGGCTGCAC TGTGAAGAAC ACGAGAGTCG GCGGAGACCT 000480
000481 GTGCCTGCTC TTCTCAGCCT CAATGTCTGG AAGACAAAAA AAGGCATCCT GCTCCCAAGA TTGTGGTGGA GGCCAGCAGG 000560
000561 GTGACGCACA TGAAAGCCAC TGGAGATAGA TGGCACTTGT TCCCACCCAC TGCCCACAAC AGGCCCAGGA CTGCCTCAGC 000640
000641 CCCGGTGGAC CCCAGAGCCA GCAGGCCCTT CAGAATGGAA GGTGCCAAAC ACCATCGGAA GGCGTGGTTC TTTTCAGAGA 000720
000721 ACCAGACTCT GAGACTGTGG CCTCCCACTA TGAGTCACCA CCTCTGATTC CTGAGGTCCC CTCCAGTCAT TGGCTCTCTC 000800
000801 CCAAGCCAGC CAGCTGATCA GCCTTGAGGA CAGCAGAGTG TCTGCCAAGA GAGATCTGTG AAGTTTCCCA TCACCGTGGC 000880
000881 AGTCCACAAT GTGAAGCCCC TGAGGCCACC CTTCTCCATG TGTCCCCCAC ACTGTCCCTG ACCCTCCCAC CATCCTAGAA 000960
000961 AACCAGCCTC CCAGGTCCTC TGTCATGGAA GTAATTTACA GCAAGGCAGA AAGAGCTGAA AGATTTATAA ATGTGTAAAA 001040
001041 TTTACAAAGG TGTTTCTTTC TTTCTTTCTT TCTTTTTTTT TTTTTTTTTT TTTGAGGCAG AGTCTCACTC TGTTGCCCAG 001120
001121 GCTGGAGTGC AGTGGCACAA TTTTGGCTCA CTGCAACCTC CGCCTCCCGG GTTCAAGTGA TTCTCCTGCC TCAGCCTCCC 001200
001201 AAGTAGCTGG GATTACAGGT GCATGCCACC ACGCCTAGCT AATTTTTGTA TTTTTAGTAG AGACAGAGTT TTTTGCCATG 001280
001281 TTGGCCAGGC TGGTCTTGAA CTCCTGACCT CAGGTGATCT GCCTGCCTCA GCCTCCCAAA GTGCTGGGAT TACAGGCGTG 001360
001361 AGTCACCGTG CCCGGCCTAC AGAGGTGTTT CTGAGTGGAG AAACCACTGC CTGGTTGGAC TGACTGCCCA GTTCCACCAC 001440
001441 CCTGTGAGCC CATGAGTGAG CTCACTGCAC TTGTTATAGA CATCCTACCA CCAGCAGCCT GATTTTGCTG AGTCCGTAGC 001520
001521 TTACAACTCC AATCTCATGG CCCTGCCTTT CACCTCACTT GCTGCCTTAA AAACCTGCAG ACTGAGGTGG CGTAGAAGCT 001600
001601 GTGACATCCC AGTACCCAGA AGTTCATCTC ACACCCAGAT CTTGGTTTCT AAATGTCATT CTCTACTAAA AGGGACCAGG 001680
001681 GCTGGTACAG GAGAAGAGCA AGAGCTTGGA ATATCTTATA CCTGAGAGTA AGGAAGTGCT CAGAGAATCA CAGGAGCACG 001760
001761 TTAAAAGGAC ATAGAAGTCA GTTTAATGAG ACTGCTTCTG GCCAAAGTTG GAACACATCA AACATTAAAA CAATGATGGT 001840
001841 AATGGATTAG ATTCCATAGA ATAAAATCCT TGAGGACATA GTTATATAAA CATAACTGAG GAAGAAGGAA AAGCTCTCCC 001920
001921 TAACAGAATA ATACAACTAG TAAATGGGAA AGGAAAGGAG TTAGGAATTC ACGCTGGGTA TTGAAACTAG TGGGTGAAAG 002000
002001 CTCAATGAAT CGGATTCTTA GTCTCAATGT CTCTCCTCTC AATTTAGTAA TT