Difference between revisions of "MIR122HG"
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Revision as of 06:01, 10 August 2019
Lnc-pri-miR-122 transcripts are capped but not polyadenylated[1].
Contents
Annotated Information
Name
MIR122HG
Alias
lnc-pri-miR-122
ID
ENSG00000267391
locus
18q21.31
Characteristic
Lnc-pri-miR-122 transcripts are capped but not polyadenylated[1] lnc-pri-miR-122 3' end is generated by Drosha cleavage and not by CPA[1] Pol II transcribing lnc-pri-miR-122 fails to recognize PAS (polyadenylation site) even when Microprocessor cleavage is inhibited.[1]
Expression
Lnc-pri-miR-122 transcripts are capped but not polyadenylated[1]
Labs working on this lncRNA
- Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Dhir A, Dhir S, Proudfoot NJ, Jopling CL. Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs. Nat Struct Mol Biol. 2015 Apr;22(4):319-27. doi: 10.1038/nsmb.2982. Epub 2015 Mar 2. PubMed PMID: 25730776; PubMed Central PMCID: PMC4492989.
