Difference between revisions of "LINC00973"

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===Characteristics ===
 
===Characteristics ===
[[File:Functional domains of 7SK RNA..png|right|thumb|Functional domains of 7SK RNA([https://www.ncbi.nlm.nih.gov/pubmed/19246988 (Diribarne 2009)])]]
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Please input characteristics information here.
  
 
===Expression===
 
===Expression===
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Please input expression information here.
  
 
===Regulation===
 
===Regulation===
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Please input regulation information here.
  
 
===Function===
 
===Function===
[[File:Model of hLarp7 recognition of the 7SK.png|right|thumb|Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP([https://www.ncbi.nlm.nih.gov/pubmed/29946027 (Eichhorn 2018)])]]
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LINC00973 were recently identified as powerful biomarkers of poor prognosis of colorectal cancer patients, predicting early tumor relapses.<ref name="ref2">
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LINC00973 may form a complex with lncRNA CRNDE. This RNA is a part of the Polycomb repressive complex 2, which epigenetically silences DUSP/CDKN1A expression, promoting proliferation and suppressing apoptosis of colon cancer cells.<ref name="ref2">
  
 
===Disease===
 
===Disease===

Revision as of 06:03, 12 August 2019

Annotation

Name

Approved symbol: LINC00973

Approved name: long intergenic non-protein coding RNA 973

HGNC ID: HGNC:48868

Alias symbols: CTD-2021J15.2

LncBook ID: HSALNT0289076

Characteristics

Please input characteristics information here.

Expression

Please input expression information here.

Regulation

Please input regulation information here.

Function

LINC00973 were recently identified as powerful biomarkers of poor prognosis of colorectal cancer patients, predicting early tumor relapses.Cite error: Closing </ref> missing for <ref> tag(1) [1](2)

</references>
  1. Zinovieva OL, Grineva EN, Prokofjeva MM, et al. Expression of long non-coding RNA LINC00973 is consistently increased upon treatment of colon cancer cells with different chemotherapeutic drugs[J]. Biochimie, 2018, 151: 67-72.