Difference between revisions of "LINC00882"
(→Function) |
|||
| Line 28: | Line 28: | ||
===Function=== | ===Function=== | ||
[[File:Model of hLarp7 recognition of the 7SK.png|right|thumb|Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP([https://www.ncbi.nlm.nih.gov/pubmed/29946027 (Eichhorn 2018)])]] | [[File:Model of hLarp7 recognition of the 7SK.png|right|thumb|Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP([https://www.ncbi.nlm.nih.gov/pubmed/29946027 (Eichhorn 2018)])]] | ||
| + | |||
| + | LINC00882 promotes HCC progression and could be a potential prognostic biomarker and therapeutic target for HCC. | ||
===Disease=== | ===Disease=== | ||
Revision as of 07:45, 12 August 2019
Contents
Annotated Information
Name
Approved symbol: LINC00882
Approved name: long intergenic non-protein coding RNA 882
HGNC ID: HGNC:10037
Previous names: HGNC:48568
RefSeq ID: NR_028303
Ensembl ID: ENSG00000242759
LncBook ID: HSALNT0058246
Chromosome
3q13.12
Characteristics
Functional domains of 7SK RNA((Diribarne 2009))
Expression
LncRNA 882 (LINC00882) is one of the lncRNAs that was significantly upregulated in HCC tissues compared with normal liver tissues.
Regulation
Function
Model of hLarp7 recognition of the 7SK 3′end and mechanism of assembly of core 7SK RNP((Eichhorn 2018))
LINC00882 promotes HCC progression and could be a potential prognostic biomarker and therapeutic target for HCC.
Disease
hepatocellular carcinoma [1]
Evolution
Please input evolution information here.
Labs working on this lncRNA
- Department of Hepatobiliary and Pancreatic Surgery, the Third Xiangya Hospital of Central South University, Changsha, Hunan 410013, People's Republic of China
- Department of Adult Stem Cells, Institute of Reproduction and Stem Cell Engineering, Central South University, Changsha, Hunan 410078, People's Republic of China
- Institute of Transformation Medicine Affiliated to Hunan Yearth Biotechnology Co., Ltd., Changsha, Hunan 410200, People's Republic of China
References
- ↑ Zhu L, Huang F, Wan T, et al. Overexpression of long noncoding RNA LINC00882 is associated with poor prognosis in hepatocellular carcinoma[J]. Onco Targets Ther, 2018, 11: 5209-5217.
Sequence
>gi|255683377|ref|NR_028303.1| Homo sapiens long intergenic non-protein coding RNA 882 (LINC00882), long non-coding RNA
000001 AGGCTCGGCG TTGGCCTCCG CGGCCCGTGC GAGTGCGCCC TTCTCGGGTC CCCTAGGTCG CGGGGCAGCC GGGGCGGAAG 000080
000081 GGGCTTGTTC ATTATTTTGA GAGTTTGTTG TGAACGTCAT AACCTTTCGT CCTTAAATAT TGCCGATACT TGACCTACGC 000160
000161 AAGAGACAAT GTCATGTGAT TCAGCCTAAT ATCTCAGAGG ATGCAGCATT CAAGGTTCTA TCTTGGAAGC AGAGACTGTG 000240
000241 CCCTCACCAG ATGCTGAACC TGCTGAGCAC CCTGATCTTC CACTTCACCT TCATCAGAAC TACTGGGGCT GTGGCTGAGA 000320
000321 TGTCACATGG CAGATAGGAT CACAAATTTC TGTTGTATCT GGATGGAGAT CAGCAGGAGG ATCTATGGAC TGCTGTGATT 000400
000401 GCACCTGCCA TCTTATGCAG AAATGACCTG AAGACAGACT GAAACAACGT GTTCTACAGC CTGAAAATAT CTACCTTGAC 000480
000481 TTACAGTTTT ATTAATGCTG GTGTGATCAG ACTGGACAAA AATTAGCATA TGTTATTAAC TGATCTAATT CAAGTGCCAA 000560
000561 TTCTTAATAG AAACACAAAA CAATAAAAGC AATTCAGAAA ATAAAAAAAA AAAAA
000081 GGGCTTGTTC ATTATTTTGA GAGTTTGTTG TGAACGTCAT AACCTTTCGT CCTTAAATAT TGCCGATACT TGACCTACGC 000160
000161 AAGAGACAAT GTCATGTGAT TCAGCCTAAT ATCTCAGAGG ATGCAGCATT CAAGGTTCTA TCTTGGAAGC AGAGACTGTG 000240
000241 CCCTCACCAG ATGCTGAACC TGCTGAGCAC CCTGATCTTC CACTTCACCT TCATCAGAAC TACTGGGGCT GTGGCTGAGA 000320
000321 TGTCACATGG CAGATAGGAT CACAAATTTC TGTTGTATCT GGATGGAGAT CAGCAGGAGG ATCTATGGAC TGCTGTGATT 000400
000401 GCACCTGCCA TCTTATGCAG AAATGACCTG AAGACAGACT GAAACAACGT GTTCTACAGC CTGAAAATAT CTACCTTGAC 000480
000481 TTACAGTTTT ATTAATGCTG GTGTGATCAG ACTGGACAAA AATTAGCATA TGTTATTAAC TGATCTAATT CAAGTGCCAA 000560
000561 TTCTTAATAG AAACACAAAA CAATAAAAGC AATTCAGAAA ATAAAAAAAA AAAAA
