Difference between revisions of "LIFR-AS1"
Chunlei Yu (talk | contribs) |
Qianpeng Li (talk | contribs) |
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==Annotated Information== | ==Annotated Information== | ||
− | === | + | |
− | ''LIFR-AS1'':LIFR antisense RNA 1 | + | ===Name=== |
+ | Approved Symbol: ''LIFR-AS1'':LIFR antisense RNA 1 | ||
+ | |||
+ | RefSeq ID: NR_103553 | ||
+ | |||
+ | Ensembl ID: ENSG00000244968 | ||
+ | |||
+ | RefSeq ID: NR_103553 | ||
+ | |||
+ | LncBook transcript ID: HSALNT0288975 | ||
===Chromosome=== | ===Chromosome=== | ||
5p13.1 | 5p13.1 | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | === | + | ===Characteristics=== |
− | ''LIFR-AS1'' is associated with higher rates of preterm birth <34 weeks. <ref name=" | + | - |
+ | ===Function=== | ||
+ | * ''LIFR-AS1'' knockdown attenuated, whereas miR-29a inhibition enhanced the cellular effect of PDT on HCT116 cell proliferation and apoptosis. Furthermore, TNFAIP3 was confirmed to be a direct target of miR-29a and exerted a similar effect to ''LIFR-AS1'' on the cellular effects of PDT. In a word, ''LIFR-AS1'' serves as a competitive endogenous RNA (ceRNA) for miR-29a to inhibit its expression and up-regulate downstream target TNFAIP3 expression, finally modulating the resistance of CRC to PDT<ref name="ref2" />. | ||
+ | |||
+ | ===Regulation=== | ||
+ | ''LIFR-AS1''and miR-29a negatively regulated each other<ref name="ref2" />. | ||
+ | ===Diseases=== | ||
+ | ''LIFR-AS1'' is associated with higher rates of preterm birth <34 weeks<ref name="ref1" />. | ||
+ | Colorectal Cancer (CRC)<ref name="ref2" /> | ||
+ | ===Expression=== | ||
+ | lncRNA ''LIFR-AS1'' was upregulated in PDT-treated HCT116 cells<ref name="ref2" />. | ||
+ | |||
+ | ===Sequence=== | ||
+ | >gi|511773009|ref|NR_103553.1| Homo sapiens LIFR antisense RNA 1 (LIFR-AS1), transcript variant 1, long non-coding RNA | ||
+ | <dnaseq>GCGCGCGGGTGCTCCAAGGAGTCGGAGGAACGCGGCCGCGCGACGGGCCCCGGACGCCGAGGGTGGTGCTTCCTCCGAGCCTCCGGTGGTGAGGCCGCTCTCAGAAGGTCATGGAAGCGCAGGGGAGAGCGAGGCGGCCGAGCCCAGGCAAATCCTCGAGAAAGGCCGAGTGCGCGACGGCTCTGCGGGGAGGACCGCGCCTCCCCGAATGCGGCCGCTGCTGCCGCTGCAAACAGTGCCTTGAGGAGAGGAAAGCGGGGAACCGTGTTTTCGCCGCCTCTGTAACCACTGCACACAAGAAAACCAGCTTCTGGGAGAGGGGGATGATTGTTGGGACTTTGCGAATTACCTAAACAGCCCAGGGCCGAGGCGCCGCCGCTCGCGTCCTGGTCCTCCTGCCGGGTGTGGGGCTCCCCTGCCCGAGATGGCCAGCGGGCGCGCCGAGAGTATCCTGGAGCCATCTAGTCTTGCCTCGGAGGCGGGGTGGGCTTATTTGTGCGGAGAAGAAACGGATCTCTTAATGGGGTGAGATTTTTCCTCCGTACATTGTTCCCATTTCCGCAGTTTCACTTGGCCTCGGTTTTCTAGCAGAGTAATCACCAAATGAAATTAGCTGGAGAGCGTTTGATGGCGCAGAATCACGGTCTGAAGATGTTTACGCTGTATGCCGGACGCGTTTGATGGTGTTCTCTTCGGCACAATTAATTTTGCAAAGTTCAGAAATGTGCCAGACAGAGCCCCTGGCACGCAGTCAGGACTCTACAGACACACCTTGAGTAGGAAACAGGCTTGTTTGTTTCATCTGTGATTTATGTGATGCACCAGCACCAAGGCCAACGTGTTTTTTAAAGACCTTTCGATGAAACTCCAAAGCAATTTATAAATTGGCAAAATGAAGCTTGTTTTGTAAAATAACTCTTCCTTGTTGATCATGTAATTAAATGGGCAACAAAACACCTGAAAGGACATTTACTGAAAAGTAGACTCCCAAAACAAAAATATGTATTTCACAGCTAGATACGGTCGCTATTAGCGTCCTAATGGCCAACTCCATCCATGTGCGTATTTTGAACACTAAAAACGCCTCCTGTTACCCCTAAGACCTTGTTTGGATAACATTTTTCTATTATAAGTACTCGAAACCAACCCCATTTAAGATGTTTACCCTTATTCTTGAGTCCTTGATGGTTTGGGAAATTTATCATTATTCATATTGCACAATCCTGTCACTGTCTTTTCCATTAGGCACAGTGCCTAAGGTCCACAATATTTTTAGAGGCCCACAAAAAATATTTTAATTTCTTTTCAAATCAGAAGGAAAAAAAATTTAGGTTTAAGAAAGTATTTTAATATATATTAATATATTTGTTTTTGTGCTAATACAATCTTAAAATGTATGTATATATGTGTGTGTGTATATGTATATATATTTTAATGGAGTAAGGGGCTCAACGAAGGCAAAAAGGCCTAGAGCCCAAGAAAAACATGATGTGGCCCTGTTGCCTGGGGTTGAAAAATCCCATTCCATGAGAAGAATTTAGTTTTAAGAATATTACATAAAATGCTCATTTCTGTGGCCTTGCTATAATAGAAAGATGGAGATTCAGAGTAGTGATAATGGCTAACATCCACCTGATACACACCATGTGTCCATTACCTCTTAATCCTCACAGCACACCTGTGAAATAGGTACTATTCTCACACTTAGGGGGTAATGCAGGTTTTGTGGGGCCTGCAATTTATGCAATTTGGGTGGTCCTCTTAAAGAAAAAGCAAATACTGTGTATTAGTCCGTTCTCACACTGCTATAAAGAACTGCGCGAGACTGGGTAATTTATAAAGGAAAGAGGTTTAATTGACTCACAGTTCCACATGGCTGGGGAGACCTCAGGAAACTTAACAATCGTGGTGGAAGGAGAAGCAAGTACCTTCTTCACAAGGAAGCGGAAAGAATTGTGAGCGGAGGAACTTGCCAAACACAAAACCGTCAGATCGCGTGAGAATTCAGTTACTATCACGAGAACAACACGGGAAAACTGTCCCCATAATCAAGTCATTTCTCTCCCTAACAAGTGAGGATTACAATTCAAGATGAGGTTTGGGTAGGAACACAAAGCCTGACCCTATCCCACAGCATGTCCAGGCTGCCCTAGCACCACCCAATAGAAGGGAAAATGGCAGAGGGAAAGTCCTAGTGGAAAGAGACCTCAGTCTCAGCTAATTGTGGTGACAATATATTGCTTTTGCAAATTGTACATAAACATATGACCAGGTGAATGTATCGCCAAGGCTCCTGCCAAGGCCTGGGATGGAGGCCTAGAGAAGATGCCCGAAAGTTTATGCTGTGTGAGCTTCACAGAAGACCTGCCTTCCATGTATACCCATTTTACAGGTGTCTGTGCGGTGCAGAAACTGTACAACTGTATACAGTGACCATTTCTACTCTGGGTCTCTAAACAAGGGCTGGTATCGTTACAGAGACTGAAGACTGAGGAAGACCATCTCTGTAGGATGCCAAGGATTGACTGGAGAAAGTCTGGCAGAATAGAACGTCTTGCACAAGAGGAGTGGAACAGCGGTCAGAGCATTACAGCTGACTCATCTTGACCAGAGAAGGTTACAGCTGGAGGCCCCAGAGATTGCCCACTTCCCCCCTCCATTTGACAGCAAGGGAAACAATGGCCAGAGAGGATCTGGAACTTTCTCTCAATTTCAGTGAAGGCCAGAGGTAAAATCAGGATTGTCTGAAGACAAGTAAGGTCAGGTGCATAGGGTTATATGTAGGAGTATAGTTAACAGGTGTCAGAAACTTGGATTTAATTTAGAGGTGGTTAGGACATGCATAATATTTTTCAACTATGCGTGAAATCTGGGATTCTGCATTTATTTAAAATATAGGATTGTCCATTAATTCTTTCTCTTGAGAGGGCGCTTCTTTCAGAAATGATCTAGGCACTTACAAACATTTTAAAAATATATACACGTGAGATCATACTTTCATAGTGATATAAGCATCATTGCTCATATCCCTAATGAACAGATGGGGAAAAGGAGGTAGAGACAGAGAGAGAGACAGAGAGTCAGCAACTCACCACAAGAATCTCCTGGTTGCCTGTCTGGGCTTCTGTCAGCTCCATTTAGTTGAATTTCTATTCAATATTATTACTGAGGTCTTATACTTAAGAACATGTTCTTTGGGTTTCCTGCTTATCTCCAAGCTGAAGAATTTATTTTCTTCTATTTGCTTTTCCAATCTTCAGCTTCCATGACCTTAAAAAAAAAAGTACACAAACTGAGCTGGTCTAAGAGCAGCCTGTTTGCAACCTGATATGAGACCTGGAATGCAACCAGATAAACCTTGGTGTAGGGTTCTCTAAACACATTCAACATTTTTTCCAAGAGGCAATCGGTTTATTTCCTTTGAAATGCTTGATGATGAATTAACAGTACATTTTCGAAACTATTGAAAGAGCAGAGGTAAAATGGTAGTTATACATGTCGGAATGGGAAATAGAGAACTATGGAATTTATCTTACTTTGAAGCTTAAACCCCTTTTAATATTCCTTGTATTTAGCCACATGTATTTTTAAGGTGGAAATTAGTTAATGGAATATTCTCATAGTCCATACTTTTTATTAAGGTTGATGTTTGATGAACCAGATAATGTCTACTCACTTTCTGCTTTAAAGTTTATAATTCTTGATAAAAGGAAAAGTGGTGAATTATGTGAGCCAACCCTGGAAAGTATTTCCGTATTGAGTTTTGTTTGTTTCAAAGAACCTACTGTACATATGCAAAAAAA</dnaseq> | ||
==Labs working on this lncRNA== | ==Labs working on this lncRNA== | ||
Line 18: | Line 35: | ||
==References== | ==References== | ||
<references> | <references> | ||
− | <ref name="ref1">Frey HA, Stout MJ, Pearson LN, Tuuli MG, Cahill AG, Strauss JF, 3rd, et al. Genetic variation associated with preterm birth in African-American women[J]. American journal of obstetrics and gynecology. 2016.</ref>(1) | + | <ref name="ref1">Frey HA, Stout MJ, Pearson LN, Tuuli MG, Cahill AG, Strauss JF, 3rd, et al. Genetic variation associated with preterm birth in African-American women[J]. American journal of obstetrics and gynecology. 2016. |
+ | </ref>(1) | ||
+ | <ref name="ref2"> | ||
+ | Liu K, Yao H, Wen Y, Zhao H, Zhou N, Lei S, Xiong L. Functional role of a long non-coding RNA LIFR-AS1/miR-29a/TNFAIP3 axis in colorectal cancer resistance to pohotodynamic therapy. Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2871-2880. | ||
+ | </ref>(2) | ||
</references> | </references> | ||
− | |||
− | |||
− |
Latest revision as of 02:51, 14 August 2019
Contents
Annotated Information
Name
Approved Symbol: LIFR-AS1:LIFR antisense RNA 1
RefSeq ID: NR_103553
Ensembl ID: ENSG00000244968
RefSeq ID: NR_103553
LncBook transcript ID: HSALNT0288975
Chromosome
5p13.1
Characteristics
-
Function
- LIFR-AS1 knockdown attenuated, whereas miR-29a inhibition enhanced the cellular effect of PDT on HCT116 cell proliferation and apoptosis. Furthermore, TNFAIP3 was confirmed to be a direct target of miR-29a and exerted a similar effect to LIFR-AS1 on the cellular effects of PDT. In a word, LIFR-AS1 serves as a competitive endogenous RNA (ceRNA) for miR-29a to inhibit its expression and up-regulate downstream target TNFAIP3 expression, finally modulating the resistance of CRC to PDT[1].
Regulation
LIFR-AS1and miR-29a negatively regulated each other[1].
Diseases
LIFR-AS1 is associated with higher rates of preterm birth <34 weeks[2]. Colorectal Cancer (CRC)[1]
Expression
lncRNA LIFR-AS1 was upregulated in PDT-treated HCT116 cells[1].
Sequence
>gi|511773009|ref|NR_103553.1| Homo sapiens LIFR antisense RNA 1 (LIFR-AS1), transcript variant 1, long non-coding RNA
000001 GCGCGCGGGT GCTCCAAGGA GTCGGAGGAA CGCGGCCGCG CGACGGGCCC CGGACGCCGA GGGTGGTGCT TCCTCCGAGC 000080
000081 CTCCGGTGGT GAGGCCGCTC TCAGAAGGTC ATGGAAGCGC AGGGGAGAGC GAGGCGGCCG AGCCCAGGCA AATCCTCGAG 000160
000161 AAAGGCCGAG TGCGCGACGG CTCTGCGGGG AGGACCGCGC CTCCCCGAAT GCGGCCGCTG CTGCCGCTGC AAACAGTGCC 000240
000241 TTGAGGAGAG GAAAGCGGGG AACCGTGTTT TCGCCGCCTC TGTAACCACT GCACACAAGA AAACCAGCTT CTGGGAGAGG 000320
000321 GGGATGATTG TTGGGACTTT GCGAATTACC TAAACAGCCC AGGGCCGAGG CGCCGCCGCT CGCGTCCTGG TCCTCCTGCC 000400
000401 GGGTGTGGGG CTCCCCTGCC CGAGATGGCC AGCGGGCGCG CCGAGAGTAT CCTGGAGCCA TCTAGTCTTG CCTCGGAGGC 000480
000481 GGGGTGGGCT TATTTGTGCG GAGAAGAAAC GGATCTCTTA ATGGGGTGAG ATTTTTCCTC CGTACATTGT TCCCATTTCC 000560
000561 GCAGTTTCAC TTGGCCTCGG TTTTCTAGCA GAGTAATCAC CAAATGAAAT TAGCTGGAGA GCGTTTGATG GCGCAGAATC 000640
000641 ACGGTCTGAA GATGTTTACG CTGTATGCCG GACGCGTTTG ATGGTGTTCT CTTCGGCACA ATTAATTTTG CAAAGTTCAG 000720
000721 AAATGTGCCA GACAGAGCCC CTGGCACGCA GTCAGGACTC TACAGACACA CCTTGAGTAG GAAACAGGCT TGTTTGTTTC 000800
000801 ATCTGTGATT TATGTGATGC ACCAGCACCA AGGCCAACGT GTTTTTTAAA GACCTTTCGA TGAAACTCCA AAGCAATTTA 000880
000881 TAAATTGGCA AAATGAAGCT TGTTTTGTAA AATAACTCTT CCTTGTTGAT CATGTAATTA AATGGGCAAC AAAACACCTG 000960
000961 AAAGGACATT TACTGAAAAG TAGACTCCCA AAACAAAAAT ATGTATTTCA CAGCTAGATA CGGTCGCTAT TAGCGTCCTA 001040
001041 ATGGCCAACT CCATCCATGT GCGTATTTTG AACACTAAAA ACGCCTCCTG TTACCCCTAA GACCTTGTTT GGATAACATT 001120
001121 TTTCTATTAT AAGTACTCGA AACCAACCCC ATTTAAGATG TTTACCCTTA TTCTTGAGTC CTTGATGGTT TGGGAAATTT 001200
001201 ATCATTATTC ATATTGCACA ATCCTGTCAC TGTCTTTTCC ATTAGGCACA GTGCCTAAGG TCCACAATAT TTTTAGAGGC 001280
001281 CCACAAAAAA TATTTTAATT TCTTTTCAAA TCAGAAGGAA AAAAAATTTA GGTTTAAGAA AGTATTTTAA TATATATTAA 001360
001361 TATATTTGTT TTTGTGCTAA TACAATCTTA AAATGTATGT ATATATGTGT GTGTGTATAT GTATATATAT TTTAATGGAG 001440
001441 TAAGGGGCTC AACGAAGGCA AAAAGGCCTA GAGCCCAAGA AAAACATGAT GTGGCCCTGT TGCCTGGGGT TGAAAAATCC 001520
001521 CATTCCATGA GAAGAATTTA GTTTTAAGAA TATTACATAA AATGCTCATT TCTGTGGCCT TGCTATAATA GAAAGATGGA 001600
001601 GATTCAGAGT AGTGATAATG GCTAACATCC ACCTGATACA CACCATGTGT CCATTACCTC TTAATCCTCA CAGCACACCT 001680
001681 GTGAAATAGG TACTATTCTC ACACTTAGGG GGTAATGCAG GTTTTGTGGG GCCTGCAATT TATGCAATTT GGGTGGTCCT 001760
001761 CTTAAAGAAA AAGCAAATAC TGTGTATTAG TCCGTTCTCA CACTGCTATA AAGAACTGCG CGAGACTGGG TAATTTATAA 001840
001841 AGGAAAGAGG TTTAATTGAC TCACAGTTCC ACATGGCTGG GGAGACCTCA GGAAACTTAA CAATCGTGGT GGAAGGAGAA 001920
001921 GCAAGTACCT TCTTCACAAG GAAGCGGAAA GAATTGTGAG CGGAGGAACT TGCCAAACAC AAAACCGTCA GATCGCGTGA 002000
002001 GAATTCAGTT ACTATCACGA GAACAACACG GGAAAACTGT CCCCATAATC AAGTCATTTC TCTCCCTAAC AAGTGAGGAT 002080
002081 TACAATTCAA GATGAGGTTT GGGTAGGAAC ACAAAGCCTG ACCCTATCCC ACAGCATGTC CAGGCTGCCC TAGCACCACC 002160
002161 CAATAGAAGG GAAAATGGCA GAGGGAAAGT CCTAGTGGAA AGAGACCTCA GTCTCAGCTA ATTGTGGTGA CAATATATTG 002240
002241 CTTTTGCAAA TTGTACATAA ACATATGACC AGGTGAATGT ATCGCCAAGG CTCCTGCCAA GGCCTGGGAT GGAGGCCTAG 002320
002321 AGAAGATGCC CGAAAGTTTA TGCTGTGTGA GCTTCACAGA AGACCTGCCT TCCATGTATA CCCATTTTAC AGGTGTCTGT 002400
002401 GCGGTGCAGA AACTGTACAA CTGTATACAG TGACCATTTC TACTCTGGGT CTCTAAACAA GGGCTGGTAT CGTTACAGAG 002480
002481 ACTGAAGACT GAGGAAGACC ATCTCTGTAG GATGCCAAGG ATTGACTGGA GAAAGTCTGG CAGAATAGAA CGTCTTGCAC 002560
002561 AAGAGGAGTG GAACAGCGGT CAGAGCATTA CAGCTGACTC ATCTTGACCA GAGAAGGTTA CAGCTGGAGG CCCCAGAGAT 002640
002641 TGCCCACTTC CCCCCTCCAT TTGACAGCAA GGGAAACAAT GGCCAGAGAG GATCTGGAAC TTTCTCTCAA TTTCAGTGAA 002720
002721 GGCCAGAGGT AAAATCAGGA TTGTCTGAAG ACAAGTAAGG TCAGGTGCAT AGGGTTATAT GTAGGAGTAT AGTTAACAGG 002800
002801 TGTCAGAAAC TTGGATTTAA TTTAGAGGTG GTTAGGACAT GCATAATATT TTTCAACTAT GCGTGAAATC TGGGATTCTG 002880
002881 CATTTATTTA AAATATAGGA TTGTCCATTA ATTCTTTCTC TTGAGAGGGC GCTTCTTTCA GAAATGATCT AGGCACTTAC 002960
002961 AAACATTTTA AAAATATATA CACGTGAGAT CATACTTTCA TAGTGATATA AGCATCATTG CTCATATCCC TAATGAACAG 003040
003041 ATGGGGAAAA GGAGGTAGAG ACAGAGAGAG AGACAGAGAG TCAGCAACTC ACCACAAGAA TCTCCTGGTT GCCTGTCTGG 003120
003121 GCTTCTGTCA GCTCCATTTA GTTGAATTTC TATTCAATAT TATTACTGAG GTCTTATACT TAAGAACATG TTCTTTGGGT 003200
003201 TTCCTGCTTA TCTCCAAGCT GAAGAATTTA TTTTCTTCTA TTTGCTTTTC CAATCTTCAG CTTCCATGAC CTTAAAAAAA 003280
003281 AAAGTACACA AACTGAGCTG GTCTAAGAGC AGCCTGTTTG CAACCTGATA TGAGACCTGG AATGCAACCA GATAAACCTT 003360
003361 GGTGTAGGGT TCTCTAAACA CATTCAACAT TTTTTCCAAG AGGCAATCGG TTTATTTCCT TTGAAATGCT TGATGATGAA 003440
003441 TTAACAGTAC ATTTTCGAAA CTATTGAAAG AGCAGAGGTA AAATGGTAGT TATACATGTC GGAATGGGAA ATAGAGAACT 003520
003521 ATGGAATTTA TCTTACTTTG AAGCTTAAAC CCCTTTTAAT ATTCCTTGTA TTTAGCCACA TGTATTTTTA AGGTGGAAAT 003600
003601 TAGTTAATGG AATATTCTCA TAGTCCATAC TTTTTATTAA GGTTGATGTT TGATGAACCA GATAATGTCT ACTCACTTTC 003680
003681 TGCTTTAAAG TTTATAATTC TTGATAAAAG GAAAAGTGGT GAATTATGTG AGCCAACCCT GGAAAGTATT TCCGTATTGA 003760
003761 GTTTTGTTTG TTTCAAAGAA CCTACTGTAC ATATGCAAAA AAA
000081 CTCCGGTGGT GAGGCCGCTC TCAGAAGGTC ATGGAAGCGC AGGGGAGAGC GAGGCGGCCG AGCCCAGGCA AATCCTCGAG 000160
000161 AAAGGCCGAG TGCGCGACGG CTCTGCGGGG AGGACCGCGC CTCCCCGAAT GCGGCCGCTG CTGCCGCTGC AAACAGTGCC 000240
000241 TTGAGGAGAG GAAAGCGGGG AACCGTGTTT TCGCCGCCTC TGTAACCACT GCACACAAGA AAACCAGCTT CTGGGAGAGG 000320
000321 GGGATGATTG TTGGGACTTT GCGAATTACC TAAACAGCCC AGGGCCGAGG CGCCGCCGCT CGCGTCCTGG TCCTCCTGCC 000400
000401 GGGTGTGGGG CTCCCCTGCC CGAGATGGCC AGCGGGCGCG CCGAGAGTAT CCTGGAGCCA TCTAGTCTTG CCTCGGAGGC 000480
000481 GGGGTGGGCT TATTTGTGCG GAGAAGAAAC GGATCTCTTA ATGGGGTGAG ATTTTTCCTC CGTACATTGT TCCCATTTCC 000560
000561 GCAGTTTCAC TTGGCCTCGG TTTTCTAGCA GAGTAATCAC CAAATGAAAT TAGCTGGAGA GCGTTTGATG GCGCAGAATC 000640
000641 ACGGTCTGAA GATGTTTACG CTGTATGCCG GACGCGTTTG ATGGTGTTCT CTTCGGCACA ATTAATTTTG CAAAGTTCAG 000720
000721 AAATGTGCCA GACAGAGCCC CTGGCACGCA GTCAGGACTC TACAGACACA CCTTGAGTAG GAAACAGGCT TGTTTGTTTC 000800
000801 ATCTGTGATT TATGTGATGC ACCAGCACCA AGGCCAACGT GTTTTTTAAA GACCTTTCGA TGAAACTCCA AAGCAATTTA 000880
000881 TAAATTGGCA AAATGAAGCT TGTTTTGTAA AATAACTCTT CCTTGTTGAT CATGTAATTA AATGGGCAAC AAAACACCTG 000960
000961 AAAGGACATT TACTGAAAAG TAGACTCCCA AAACAAAAAT ATGTATTTCA CAGCTAGATA CGGTCGCTAT TAGCGTCCTA 001040
001041 ATGGCCAACT CCATCCATGT GCGTATTTTG AACACTAAAA ACGCCTCCTG TTACCCCTAA GACCTTGTTT GGATAACATT 001120
001121 TTTCTATTAT AAGTACTCGA AACCAACCCC ATTTAAGATG TTTACCCTTA TTCTTGAGTC CTTGATGGTT TGGGAAATTT 001200
001201 ATCATTATTC ATATTGCACA ATCCTGTCAC TGTCTTTTCC ATTAGGCACA GTGCCTAAGG TCCACAATAT TTTTAGAGGC 001280
001281 CCACAAAAAA TATTTTAATT TCTTTTCAAA TCAGAAGGAA AAAAAATTTA GGTTTAAGAA AGTATTTTAA TATATATTAA 001360
001361 TATATTTGTT TTTGTGCTAA TACAATCTTA AAATGTATGT ATATATGTGT GTGTGTATAT GTATATATAT TTTAATGGAG 001440
001441 TAAGGGGCTC AACGAAGGCA AAAAGGCCTA GAGCCCAAGA AAAACATGAT GTGGCCCTGT TGCCTGGGGT TGAAAAATCC 001520
001521 CATTCCATGA GAAGAATTTA GTTTTAAGAA TATTACATAA AATGCTCATT TCTGTGGCCT TGCTATAATA GAAAGATGGA 001600
001601 GATTCAGAGT AGTGATAATG GCTAACATCC ACCTGATACA CACCATGTGT CCATTACCTC TTAATCCTCA CAGCACACCT 001680
001681 GTGAAATAGG TACTATTCTC ACACTTAGGG GGTAATGCAG GTTTTGTGGG GCCTGCAATT TATGCAATTT GGGTGGTCCT 001760
001761 CTTAAAGAAA AAGCAAATAC TGTGTATTAG TCCGTTCTCA CACTGCTATA AAGAACTGCG CGAGACTGGG TAATTTATAA 001840
001841 AGGAAAGAGG TTTAATTGAC TCACAGTTCC ACATGGCTGG GGAGACCTCA GGAAACTTAA CAATCGTGGT GGAAGGAGAA 001920
001921 GCAAGTACCT TCTTCACAAG GAAGCGGAAA GAATTGTGAG CGGAGGAACT TGCCAAACAC AAAACCGTCA GATCGCGTGA 002000
002001 GAATTCAGTT ACTATCACGA GAACAACACG GGAAAACTGT CCCCATAATC AAGTCATTTC TCTCCCTAAC AAGTGAGGAT 002080
002081 TACAATTCAA GATGAGGTTT GGGTAGGAAC ACAAAGCCTG ACCCTATCCC ACAGCATGTC CAGGCTGCCC TAGCACCACC 002160
002161 CAATAGAAGG GAAAATGGCA GAGGGAAAGT CCTAGTGGAA AGAGACCTCA GTCTCAGCTA ATTGTGGTGA CAATATATTG 002240
002241 CTTTTGCAAA TTGTACATAA ACATATGACC AGGTGAATGT ATCGCCAAGG CTCCTGCCAA GGCCTGGGAT GGAGGCCTAG 002320
002321 AGAAGATGCC CGAAAGTTTA TGCTGTGTGA GCTTCACAGA AGACCTGCCT TCCATGTATA CCCATTTTAC AGGTGTCTGT 002400
002401 GCGGTGCAGA AACTGTACAA CTGTATACAG TGACCATTTC TACTCTGGGT CTCTAAACAA GGGCTGGTAT CGTTACAGAG 002480
002481 ACTGAAGACT GAGGAAGACC ATCTCTGTAG GATGCCAAGG ATTGACTGGA GAAAGTCTGG CAGAATAGAA CGTCTTGCAC 002560
002561 AAGAGGAGTG GAACAGCGGT CAGAGCATTA CAGCTGACTC ATCTTGACCA GAGAAGGTTA CAGCTGGAGG CCCCAGAGAT 002640
002641 TGCCCACTTC CCCCCTCCAT TTGACAGCAA GGGAAACAAT GGCCAGAGAG GATCTGGAAC TTTCTCTCAA TTTCAGTGAA 002720
002721 GGCCAGAGGT AAAATCAGGA TTGTCTGAAG ACAAGTAAGG TCAGGTGCAT AGGGTTATAT GTAGGAGTAT AGTTAACAGG 002800
002801 TGTCAGAAAC TTGGATTTAA TTTAGAGGTG GTTAGGACAT GCATAATATT TTTCAACTAT GCGTGAAATC TGGGATTCTG 002880
002881 CATTTATTTA AAATATAGGA TTGTCCATTA ATTCTTTCTC TTGAGAGGGC GCTTCTTTCA GAAATGATCT AGGCACTTAC 002960
002961 AAACATTTTA AAAATATATA CACGTGAGAT CATACTTTCA TAGTGATATA AGCATCATTG CTCATATCCC TAATGAACAG 003040
003041 ATGGGGAAAA GGAGGTAGAG ACAGAGAGAG AGACAGAGAG TCAGCAACTC ACCACAAGAA TCTCCTGGTT GCCTGTCTGG 003120
003121 GCTTCTGTCA GCTCCATTTA GTTGAATTTC TATTCAATAT TATTACTGAG GTCTTATACT TAAGAACATG TTCTTTGGGT 003200
003201 TTCCTGCTTA TCTCCAAGCT GAAGAATTTA TTTTCTTCTA TTTGCTTTTC CAATCTTCAG CTTCCATGAC CTTAAAAAAA 003280
003281 AAAGTACACA AACTGAGCTG GTCTAAGAGC AGCCTGTTTG CAACCTGATA TGAGACCTGG AATGCAACCA GATAAACCTT 003360
003361 GGTGTAGGGT TCTCTAAACA CATTCAACAT TTTTTCCAAG AGGCAATCGG TTTATTTCCT TTGAAATGCT TGATGATGAA 003440
003441 TTAACAGTAC ATTTTCGAAA CTATTGAAAG AGCAGAGGTA AAATGGTAGT TATACATGTC GGAATGGGAA ATAGAGAACT 003520
003521 ATGGAATTTA TCTTACTTTG AAGCTTAAAC CCCTTTTAAT ATTCCTTGTA TTTAGCCACA TGTATTTTTA AGGTGGAAAT 003600
003601 TAGTTAATGG AATATTCTCA TAGTCCATAC TTTTTATTAA GGTTGATGTT TGATGAACCA GATAATGTCT ACTCACTTTC 003680
003681 TGCTTTAAAG TTTATAATTC TTGATAAAAG GAAAAGTGGT GAATTATGTG AGCCAACCCT GGAAAGTATT TCCGTATTGA 003760
003761 GTTTTGTTTG TTTCAAAGAA CCTACTGTAC ATATGCAAAA AAA
Labs working on this lncRNA
- Department of Obstetrics and Gynecology, Ohio State University, Columbus, OH. Electronic address: Heather.Frey@osumc.edu.
References
- ↑ 1.0 1.1 1.2 1.3 Liu K, Yao H, Wen Y, Zhao H, Zhou N, Lei S, Xiong L. Functional role of a long non-coding RNA LIFR-AS1/miR-29a/TNFAIP3 axis in colorectal cancer resistance to pohotodynamic therapy. Biochim Biophys Acta Mol Basis Dis. 2018 Sep;1864(9 Pt B):2871-2880.
- ↑ Frey HA, Stout MJ, Pearson LN, Tuuli MG, Cahill AG, Strauss JF, 3rd, et al. Genetic variation associated with preterm birth in African-American women[J]. American journal of obstetrics and gynecology. 2016.