Difference between revisions of "DBCCR1"

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(Labs working on this lncRNA)
 
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==Labs working on this lncRNA==
 
==Labs working on this lncRNA==
 
Division of Innovative Research, Creative Research Initiative Sousei, Hokkaido University Sapporo 001-0020, Japan([https://www.ncbi.nlm.nih.gov/pubmed/15193422 (Toshiyuki N 2004)]).
 
Division of Innovative Research, Creative Research Initiative Sousei, Hokkaido University Sapporo 001-0020, Japan([https://www.ncbi.nlm.nih.gov/pubmed/15193422 (Toshiyuki N 2004)]).
 +
 
ICRF Cancer Medicine Research Unit, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, United Kingdom([https://www.ncbi.nlm.nih.gov/pubmed/10444335 (Nishiyama H 1999)]).
 
ICRF Cancer Medicine Research Unit, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, United Kingdom([https://www.ncbi.nlm.nih.gov/pubmed/10444335 (Nishiyama H 1999)]).
 +
 
Molecular Genetics Laboratory, Marie Curie Research Institute, Surrey, UK([https://www.ncbi.nlm.nih.gov/pubmed/9175739 (Habuchi T 1997)]).
 
Molecular Genetics Laboratory, Marie Curie Research Institute, Surrey, UK([https://www.ncbi.nlm.nih.gov/pubmed/9175739 (Habuchi T 1997)]).

Latest revision as of 06:13, 13 September 2019

Annotated Information

Name

Approved symbol: BRINP1

Approved name: BMP/retinoic acid inducible neural specific 1

HGNC ID: HGNC:2687

Previous names: deleted in bladder cancer chromosome region candidate 1, deleted in bladder cancer 1, bone morphogenetic protein/retinoic acid inducible neural-specific 1

Previous symbols: DBCCR1, DBC1

Alias symbols: FAM5A

RefSeq ID: NM_014618

Characteristics

BRINP1 is a prototype member of the subsequently identified BRINP family of sequentially related neural-specific proteins including BRINP2 and BRINP3, located on chromosome 9q 32–33, between D9S1848 and AFMA239XA9a((Nishiyama H 1999)), putative tumor suppressor locus whose deletion is frequently observed in bladder tumors((Toshiyuki N 2004)).

Expression

BRINP1 is most highly and widely expressed in various regions of the mammalian nervous system, although its expression is also found in some non-neural tissues and cell types at low levels((Toshiyuki N 2004)).

Regulation

Hypermethylation of the BRINP1-CpG island suppresses BRINP1 expression in NIH 3T3 cells((Toshiyuki N 2004)).

Disease

bladder cancer((Nishiyama H 1999))

Labs working on this lncRNA

Division of Innovative Research, Creative Research Initiative Sousei, Hokkaido University Sapporo 001-0020, Japan((Toshiyuki N 2004)).

ICRF Cancer Medicine Research Unit, St. James's University Hospital, Beckett Street, Leeds, LS9 7TF, United Kingdom((Nishiyama H 1999)).

Molecular Genetics Laboratory, Marie Curie Research Institute, Surrey, UK((Habuchi T 1997)).