Difference between revisions of "SPATA8"

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===Expression===
 
===Expression===
[[File:SPATA8.png|thumb|550px|SPATA8 transcript in different developmental stages of testis and sperm.<ref name="ref1"/>
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[[File:SPATA8.png|thumb|550px|SPATA8 transcript in different developmental stages of testis and sperm.<ref name="ref1"/>]]
 
Levels of SPATA8 transcript in different developmental stages of human testis  was observed in adult testis, moderate expression in sperm, and low expres sion in foetal testis.<ref name="ref1"/>
 
Levels of SPATA8 transcript in different developmental stages of human testis  was observed in adult testis, moderate expression in sperm, and low expres sion in foetal testis.<ref name="ref1"/>
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===Disease===
 
===Disease===
 
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Latest revision as of 10:52, 21 February 2021

SPATA8 is expressed only in human testis that may play an essential role in testis function.[1]

Annotated Information

Name

Approved symbol:SPATA8

Approved name:spermatogenesis associated 8

HGNC ID:28676

Alias symbol:MGC44294|SRG8

RefSeq ID:NR_158223

Characteristics

location:15q26.2 SPATA8 gene have a 1.1-kb transcript.[1] SPATA8 expression can accelerate traversal through the S phase and entry into G2.[1] SPATA8 protein is mostly found in the cell nucleus.[1]

Function

SPATA8 could accelerate cell growth.[1]

Regulation

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Expression

SPATA8 transcript in different developmental stages of testis and sperm.[1]

Levels of SPATA8 transcript in different developmental stages of human testis was observed in adult testis, moderate expression in sperm, and low expres sion in foetal testis.[1]

Disease

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Labs working on this lncRNA=

  • Department of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Hunan, YueYang 414000, China. [1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Nie D, Xiang Y. Molecular cloning and characterization of a novel human testis-specific gene by use of digital differential display. J Genet. 2006 Apr;85(1):57-62. doi: 10.1007/BF02728971. PMID: 16809841.