NONHSAT034251

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Annotated Information

Transcriptomic Nomeclature

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Function

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Regulation

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Expression

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Allelic Information and Variation

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Evolution

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Labs working on this lncRNA

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References

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Basic Information

Transcript ID	NONHSAT034251
Source	NONCODE4.0
Same with	,
Classification	intergenic
Length	1472 nt
Genomic location	chr13+:70681345..70713885
Exon number	5
Exons	70681345..70681873,70689273..70689430,70703916..70704016,70704810..70704980,70713373..70713885
Genome context
Sequence	000001 ATCCTTCACC TGTTGCCTGG CTAGAGTTGT CTGGCTCCAC TTTGAGCTCT TGCAGAACCA GCCCTTTTTC GTGTGGTCCA 000080 000081 GGAAAGTCCA TGCCTGGCAC CACCTCCTCC TCTAGTGACT CCACGTAGAA GAGAGTCCTG GCTGGCTGCT GAGTGCCCTG 000160 000161 CCCAGGAGCC CCTTGCTGCA GCCTCGTGGC AACTGGAAGC AGGGTGCCAT TCAGCGGATT GAAGGAAGAG GAGGAAGAGG 000240 000241 ACGGGGAGGA CGATGAAGAG GAAGAGGAGG AAGGCTTCTT CCAGAAAGTG CTCACACCGC TTCTCTCTTG GCTTTTGAGC 000320 000321 AGGCGACTCT GGCTGGGTCC CCAGTGCTCA AAGCTGCCAC TGCCGTCCTG TTGCAGGCAG CCTCCCCCCG CCGGGCCGCC 000400 000401 GGTGGAAGGA GACGGGTGGC TGAAGAGTTT CCAGCGGAGT CGCAGAATGT GCTTCACATC GAAGTCTTTT CGCCCAGAGC 000480 000481 CTGACATGCT TTACGCACAG AAGGCAAAAG GCTGGCAGCT CACGCAGGAT TCTGGAGGCT GGGAAGTTCA AGACCAATGC 000560 000561 ACGAGAATTT GGTCTAAAGA GAATCTTCTT GCTCTGAACA CACATAGTAG AAGGCAGAAG GGCAAGAGAG AGAACAAAGT 000640 000641 CTGTGTCTCC ACATGGCAGA AGAGCAGAGG AGACAGAACC TACTCCTCTA TGGCAACCAC CCCATCAATG ACAAAAATCC 000720 000721 TAGAAGGATG TATGTATAGG AAGTTGAAGT GTTGAGAAGA GAATGGCTCA GAGTCAAGCG GGAACAAGAT TCAAACTTCA 000800 000801 GAGAGAGAGG GAAGAAAAAC ATTTAAATAT ATCTGGCATA ATCCAAGACT ATTTACGACA AGTGTTCTGT GTTTCTAATA 000880 000881 ATAAAACAGA CTTCACCTCG GAGTACCTGC AGAACTGGGA CCCCAATGAC CAGGGAGAAT GAAGAACAAC TTGTTGAAGA 000960 000961 TTGCCTTTTC TGACTCCCAG CTTCCACGGA GAGATTAACT CTGTTGGCTG AAGCCCTATT CCCAATTCCT TGGCTAGACC 001040 001041 CTGGGTCCTT CATGTTAGAA AACCTGGCTT TACTACTACT ACTACTACTA CTACTACTAC TACTGCTGCT GCTGCTGCTG 001120 001121 CTGCTGCTGC TGCTGCTGCT GCTGCTGCAT TTTTTAAAAA TATATTATCT TATTTTACTA TTTGATGTTA TAATTGTTAT 001200 001201 ATATTTTTCC ACACTTCCTC ATACTGCTTA TCTCTTACTT AAGAATTTAT GAATAAAGAA TTGATTTTTC AATACATCCT 001280 001281 TCCAAAAATT ATCTGATGTT GAGTTAGTTG CTCTCTCTTG TGCATTCTCA GTCCTCACAA GCCTTTCTCA AACACAATGT 001360 001361 TTATCAAAGA AAATTGTAGC AACCAATATA CTTAGTGGAA TTTCTCACAG AGTTTGAGTG TAGGAAACAG TATTCACTGT 001440 001441 ATATTAGTCA TTTTGCTCCC AATAGAAGGT GC

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Annotation (From lncRNAdb)

[NONHSAT034251]

Section	Description
ID	SCA8
Characteristics	~1.5kb spliced transcript. Antisense to the KLHL1 gene (homolog of the Drosophila KELCH gene) in a bidirectional transcriptional orientation (overlapping in the first exon).
Expression	N/A
Function	Ectopic expression in Drosophila induces late-onset, progressive neurodegeneration in the retina. Predicted gene product underpinning the triplet repeat expansion-induced neurodegenerative disease Spinocerebellar Ataxia 8. Associates with the RNA binding protein staufen.
Conservation	KLHL1AS promoter is conserved between human and mouse. However, the mouse gene is not spliced.
Name	Spinocerebellar ataxia 8 (SCA8) RNA. KLHL1AS: kelch-like 1 (Drosophila) antisense. ATXN8OS: ataxin 8 opposite strand

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