Difference between revisions of "Lnc-CRYBA4-2:1"

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==Annotated Information==
 
==Annotated Information==
 +
===Name===
 +
Gomafu
 +
 +
===Characteristics===
 +
Please input characteristics information here.
 +
 +
===Function===
 +
Gomafu can bind the splicing factor 1 (SF1) protein through its UACUAAC repeat sequences. This sequence is a much stronger intron branch point sequence than found in most mammalian introns. In-vitro Gomafu binding to SF1 can inhibit splicing and spliceosomal complex formation suggesting Gomafu can function to regulate splicing efficiency ([http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011))]. Regulates retinal cell fate specification [http://www.ncbi.nlm.nih.gov/pubmed/20459797 (Rapicavoli (2010))]. Variants confer susceptibility to myocardial infarction, possibly through altering the RNA's protein binding properties [http://www.ncbi.nlm.nih.gov/pubmed/17066261 (Ishii (2006))]. Probable target of transcription factor Oct4 in mESCs. Appears to maintain Oct4 expression in a feedback loop helping to maintain pluripotency [http://www.ncbi.nlm.nih.gov/pubmed/20026622 (Sheik Mohamed (2010))]. 
 +
 +
===Expression===
 +
Expressed predominantly in the nervous system ([http://www.ncbi.nlm.nih.gov/pubmed/17066261 Ishii (2006)], [http://www.ncbi.nlm.nih.gov/pubmed/17623775 Sone (2007)], [http://www.ncbi.nlm.nih.gov/pubmed/18184812 Mercer (2008)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]). Shows dynamic regulation during retinal development [http://www.ncbi.nlm.nih.gov/pubmed/15226823 (Blackshaw (2004))], differentiation of neural stem cells into oligodendrocytes [http://www.ncbi.nlm.nih.gov/pubmed/20137068 (Mercer (2010))] and in mouse embryonic stem cell (mESC) differentiation [http://www.ncbi.nlm.nih.gov/pubmed/20026622 (Sheik Mohamed (2010))][http://www.ncbi.nlm.nih.gov/pubmed/18562676 (Dinger (2008))]. Expressed in the nucleus accumbens of normal human brains and one of a few genes up-regulated in this brain region in both cocaine and heroin abusers ([http://www.ncbi.nlm.nih.gov/pubmed/16710320 Albertson (2006)], [http://www.ncbi.nlm.nih.gov/pubmed/21128942 Michelhaugh (2010)]). Nuclear specific localisation to novel nuclear matrix subdomain [http://www.ncbi.nlm.nih.gov/pubmed/17623775 (Sone (2007))].
 +
 +
===Conservation===
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Well conserved in placental mammals, present in chicken and appears to be conserved back to amphibians ([http://www.ncbi.nlm.nih.gov/pubmed/20459797 Rapicavoli (2010)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]). Outside of mammals sequence conservation is low but the SF1 binding UACUAAC repeats are conserved ([http://www.ncbi.nlm.nih.gov/pubmed/20459797 Rapicavoli (2010)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]).
 +
 +
===Misc===
 +
Please input misc information here.
 +
 
===Transcriptomic Nomeclature===
 
===Transcriptomic Nomeclature===
 
Please input transcriptomic nomeclature information here.
 
Please input transcriptomic nomeclature information here.
 
===Function===
 
Please input function information here.
 
  
 
===Regulation===
 
===Regulation===
 
Please input regulation information here.
 
Please input regulation information here.
 
===Expression===
 
Please input expression information here.
 
  
 
===Allelic Information and Variation===
 
===Allelic Information and Variation===
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}}
 
}}
 
[[Category:Intergenic]]
 
[[Category:Intergenic]]
 
{{lncrnadb|
 
tID = lnc-CRYBA4-2:1|
 
ltID = Gomafu|
 
ann = <tab class=wikitable sep=tab head=top>
 
Section Description
 
ID Gomafu
 
Expression Expressed predominantly in the nervous system ([http://www.ncbi.nlm.nih.gov/pubmed/17066261 Ishii (2006)], [http://www.ncbi.nlm.nih.gov/pubmed/17623775 Sone (2007)], [http://www.ncbi.nlm.nih.gov/pubmed/18184812 Mercer (2008)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]). Shows dynamic regulation during retinal development [http://www.ncbi.nlm.nih.gov/pubmed/15226823 (Blackshaw (2004))], differentiation of neural stem cells into oligodendrocytes [http://www.ncbi.nlm.nih.gov/pubmed/20137068 (Mercer (2010))] and in mouse embryonic stem cell (mESC) differentiation [http://www.ncbi.nlm.nih.gov/pubmed/20026622 (Sheik Mohamed (2010))][http://www.ncbi.nlm.nih.gov/pubmed/18562676 (Dinger (2008))]. Expressed in the nucleus accumbens of normal human brains and one of a few genes up-regulated in this brain region in both cocaine and heroin abusers ([http://www.ncbi.nlm.nih.gov/pubmed/16710320 Albertson (2006)], [http://www.ncbi.nlm.nih.gov/pubmed/21128942 Michelhaugh (2010)]). Nuclear specific localisation to novel nuclear matrix subdomain [http://www.ncbi.nlm.nih.gov/pubmed/17623775 (Sone (2007))].
 
Function Gomafu can bind the splicing factor 1 (SF1) protein through its UACUAAC repeat sequences. This sequence is a much stronger intron branch point sequence than found in most mammalian introns. In-vitro Gomafu binding to SF1 can inhibit splicing and spliceosomal complex formation suggesting Gomafu can function to regulate splicing efficiency ([http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011))]. Regulates retinal cell fate specification [http://www.ncbi.nlm.nih.gov/pubmed/20459797 (Rapicavoli (2010))]. Variants confer susceptibility to myocardial infarction, possibly through altering the RNA's protein binding properties [http://www.ncbi.nlm.nih.gov/pubmed/17066261 (Ishii (2006))]. Probable target of transcription factor Oct4 in mESCs. Appears to maintain Oct4 expression in a feedback loop helping to maintain pluripotency [http://www.ncbi.nlm.nih.gov/pubmed/20026622 (Sheik Mohamed (2010))]. 
 
Conservation Well conserved in placental mammals, present in chicken and appears to be conserved back to amphibians ([http://www.ncbi.nlm.nih.gov/pubmed/20459797 Rapicavoli (2010)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]). Outside of mammals sequence conservation is low but the SF1 binding UACUAAC repeats are conserved ([http://www.ncbi.nlm.nih.gov/pubmed/20459797 Rapicavoli (2010)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]).
 
</tab>|
 
}}
 

Revision as of 08:02, 9 October 2014

Please input one-sentence summary here.

Annotated Information

Name

Gomafu

Characteristics

Please input characteristics information here.

Function

Gomafu can bind the splicing factor 1 (SF1) protein through its UACUAAC repeat sequences. This sequence is a much stronger intron branch point sequence than found in most mammalian introns. In-vitro Gomafu binding to SF1 can inhibit splicing and spliceosomal complex formation suggesting Gomafu can function to regulate splicing efficiency (Tsuiji (2011)). Regulates retinal cell fate specification (Rapicavoli (2010)). Variants confer susceptibility to myocardial infarction, possibly through altering the RNA's protein binding properties (Ishii (2006)). Probable target of transcription factor Oct4 in mESCs. Appears to maintain Oct4 expression in a feedback loop helping to maintain pluripotency (Sheik Mohamed (2010)).

Expression

Expressed predominantly in the nervous system (Ishii (2006), Sone (2007), Mercer (2008), Tsuiji (2011)). Shows dynamic regulation during retinal development (Blackshaw (2004)), differentiation of neural stem cells into oligodendrocytes (Mercer (2010)) and in mouse embryonic stem cell (mESC) differentiation (Sheik Mohamed (2010))(Dinger (2008)). Expressed in the nucleus accumbens of normal human brains and one of a few genes up-regulated in this brain region in both cocaine and heroin abusers (Albertson (2006), Michelhaugh (2010)). Nuclear specific localisation to novel nuclear matrix subdomain (Sone (2007)).

Conservation

Well conserved in placental mammals, present in chicken and appears to be conserved back to amphibians (Rapicavoli (2010), Tsuiji (2011)). Outside of mammals sequence conservation is low but the SF1 binding UACUAAC repeats are conserved (Rapicavoli (2010), Tsuiji (2011)).

Misc

Please input misc information here.

Transcriptomic Nomeclature

Please input transcriptomic nomeclature information here.

Regulation

Please input regulation information here.

Allelic Information and Variation

Please input allelic information and variation information here.

Evolution

Please input evolution information here.

You can also add sub-section(s) at will.

Labs working on this lncRNA

Please input related labs here.

References

Please input cited references here.

Basic Information

Transcript ID

lnc-CRYBA4-2:1

Source

LNCipedia2.1

Same with

,

Classification

intergenic

Length

10193 nt

Genomic location

chr22+:27042391..27072440

Exon number

,

Exons

,

Genome context

Sequence
000001 CAGCTACAAA GACGACGCCG GCTGCGCTCG CGGGACCAGA GGGAGGGAGG CTGCGGACGA GTGCGGGGAG GAGTTTGAGA 000080
000081 TGGGAGGCGC TTGCAGGGGC TCCCCCAGTT CTGCGCTGTG AGCCGGGGCA CAAAGAGCCC TCTGCACTAG CGCCGCAGGA 000160
000161 CCGCGGACCC GAGTTGGAGG CATCTGTCCA CCCATGTGGT TCCAGACACG TTCATGTGGC CACCATGACC CCGTCGGCAT 000240
000241 CACAGGGGTA ACCAAGGTCC ACAGAACGAG GGGAAAGGGT CACTGTGGAT CAAGCCAGGC TCCTCTGAGC AGTCCAGGGT 000320
000321 CTATTTACAG AGAGCAGCAA GTTCCTGGGA CAGAGGAGAC AGAAGGGAAT TTCCAGGTTC TTCAGGACGT TCACAACCAC 000400
000401 ACTGAGAAGC ATCTTTGCAG ATAAGTATTT AAACTTACCA GCCCATAGCC TACCAGCCTG CCCTCTTCTG GTCTGTGCAG 000480
000481 GAAAGTGTAG TATCCTAGAA TGCCAAAGTG GGAGGGGAAA TGGGTGATGT AGCTCATTCT CTTTTCTACC TCTATGGAAG 000560
000561 AAAGAAAGAG CCTGTCCCCA TTTTGTGGGG TCCCAGAAAG GGTGATTTTC ACACTTCACA TTTGGCGTTA GGGCTAGTAT 000640
000641 TTCACAAACA TTACCGTCTG GAACTTTTGA AGGCTGAGTT AAATGACTTC ATCTTGTGTA CTTGTAGAAC TGCTATTAGA 000720
000721 AGGAGGCTGG GGACTCCCTG ATGATGTGAA CCAGCCCTTC TCTTCTCAGT TTCAGCACTT TGTGATCATA TTTATAAACC 000800
000801 TTGGACAGGG CTCCTTGGCC TTAGAGTTAA GTGAAGAGTT AACACTGTGA CTTTAGATGC ATTTTTCTCA GTGTAAGTGT 000880
000881 CTGAGCTCAT CTCCAGTTCT GGACTCGTGC CCCCACTCCC GGGTGCTGAC AGCAAGCTCT GAAGATATGC TGAGAGAGCT 000960
000961 CCCTGACTCT CCTGACTCAG GTCTGCCAGT TGATGAAGAC AGCACAGTTG TTACCAAAAA CAAAACCTGG CAGATGGTCC 001040
001041 TAGGTCAGGA TTAGTGGTCA TTCTCTGGTC TTCTCCAGAC TGGTGACACA GGGTGGTCTT AAAAGAGTCC TAGTCCAGCC 001120
001121 TCTGGCTCCC CGAATTTCCT CTGGTGCATG GGGCATCAGG AAAGGGCAGG GGAGAAGGAG GGGGAGCAGA AAAATAACTG 001200
001201 AGGCTGGGCA GAAGGGTCCC TTCCATTTCC CATCCATTGC TTCAAACAAT GGGTGATTAC CGTGCACCTT GAGTGAATGT 001280
001281 CAAGGCAGGA AGGGTTCCAG GGCCACCCAG TGTGGCAGGA GCAGAGCTGG GATCAGAATT CTGGATTCCT GACTCTCCGT 001360
001361 TCAGCTGCTA TTCAGCTATC ACCAAGCTGC TGAGTTTGTC CTACTTTCTC CTGGGTCACA TTCTGCTGTT GTTGGGAAAC 001440
001441 AGGGAGTGAG TGAAGGGAAC CTGGGAACCC TTCTCCCCTC ACCTTTTAAG GATGTTCTGG GGTGGAATAA AGAGAGGTGG 001520
001521 AGGGTGGGGT GCCTGGCCCA GCCTCCCTGG CTCCTGGTCC TTCTTTCTTC AGCAGGGAGT TCTGGCAAGG CCTGGGCCTG 001600
001601 GGGAGGGGGC CTGGGTGCAG TTTTCTCCTG CGGTGTGGTT GGCTCTTTTG TCTTCCAGGA TGGGCCTGTG GGGTCTGTGT 001680
001681 GGGGAAGGAA GGAGCTGGGA GCCTGGGCTG CCTGTGTGTC GGCTGGATGC TGCCAGCACC GGCATGGACC AAGCAACTTC 001760
001761 TCTGAGCCAG ATGCTGGGGA CGCAGAGGTG AACCCAGAGA CATGATCCCA TCTGCTCAGA TCTTCATGTC AGAACACGCT 001840
001841 TTATTACAGT CTCGGCAAGG GGGTGGCTCC ATCTGGGCCG CATCTCCAGG ACTCCTGGCC TGGACTTCTC TTTGGACCTC 001920
001921 GGGTGACCTT GGATTCTGGC CACAGTGACT TAGCGGTCAG ACTCCGGTGG TTTTCTAGCC CGCTGGGTGA CTCCCTGAAG 002000
002001 ATCTCATCCT CTTCACACCT GTTGGGATGG AGCCTCCCAT GGATAGGAAC TCTTCCTGGT TGATGCTCAG CAGATGACTG 002080
002081 ATCTGGCTCT GGAGGACAGC TCCAGGGGTA TGAGGGAGGC CTGGCAGCCC ACTACTCCCT CCTCACCTGC TCGGGCCCTG 002160
002161 CCTGCTGGGC CCTATTGTCT GGGTCTGGGG GCCCTTTCCT GCCCCATGTG AACTTGATTC CTCCTCGCGT TTCTGCCGGT 002240
002241 GACCAGACAG AGCCTGGCCT GGGCCAAGTC CCCACTGACC ACACTTTCCC CAAGGCTGGG TCTCAAAGGA CCCTACAGGA 002320
002321 TGGGGACAGG AACAAGGATG GGAGTCGGGG AGGGGCTGTC AGGCAGAGGG CAGATGCAGC TCCTCGGGTG CCGCTGGCTG 002400
002401 GAGTCCTTTG TCTCCATTTG CTCAGTGCGT AATTGTCATT TTGTGGGGGA CTTCCTTGGT GGGGCTTTTC CATGCTTTTC 002480
002481 CTCTCCCTGA TGGTTACAAA GAGGAGACAG TCAGGATCTG GGAGGAGCTG GAGCCTTCCC CCTGTGCTGT TGAACTCTGG 002560
002561 GAGGGGCAGC CAGAGGGGCT GAGAGTGCAC CATCCTGAAA AGAGAGGGTC TTTAAGAGAT AAGATTTAGG CTAGGGAAAT 002640
002641 TCACTAGAAA GAGACAGGTG GCCCTGGGTT TTTTTTCCTG CCATCCAAAG GGAACCAGTC TTACCCAAAG GCTTAAGGGG 002720
002721 TCACCTTAGC CCAGTCTCAG GACACTCTTC TCCAATCAGA TCGCTGCTTC TAGTTGCACT GCTCCTGGAT TCTGTTCTTG 002800
002801 GGGAACAGAA GGTGGCAGGA CAGGCCCCAC AATCTGCAAT TCCAGCTCCC TCCAGAGGAG ACAGTCCCAG CGTTTGCAAG 002880
002881 AGAGCAGCTT GTGGCCTCCC TTAGGCAAGT TTAAAAGCCA GATGTCCTTT TTCCCAGAAT GCGGAGTGGT GTGTACTATT 002960
002961 CATCAGCTTG GGCTGCCACA GCACCATGCC AGACTGGATG GCTTAAACAT CAGGAATTTA TTTTCTGCCA GTTCTGGAGG 003040
003041 CTGGAAAGTC CAGATCAAGG TGTTAAGACT TGGTTTCTGG TGAGGCCTCT CTCCTTGGCT TGCAGGTGGC ACCTTCTCAC 003120
003121 TATGTCCTCA CATGGCCTTT TCTCTGTGGA GAGGGACAGA GAGCATGAGC AGGCTCTGGT GTCTCCTCCT CTTCTTATAA 003200
003201 AGACACTAAT ATCACCATAT TAGGGCTTAA ACCTATGACC TCATTTAACC TTAACCCCTT AAAGGTCCCA TCTCCAAAAA 003280
003281 CAGTCACATA GCAGGCTACT GCTTCAACAT ATGCATTTGG GGGAGGGGAC ACCATTCAGT TCTTAACAGG GTGGTCACCG 003360
003361 CAAACATGGA AAGTCAGAGC CTTCTCCCCT TCAGAATTCC CGCCCCCACC CAGGGATGGG GAGGAGGAGC AGAGAGGTAT 003440
003441 GGGAAGCAGA CACGGAGAGT GGCAGGTACC ATGCTGGGGT GGCTCAGGAG TGCTTCGGAG GACATATGGA ACTGGCAGGG 003520
003521 CTCAGTGCAG GGAGGCGGAG GCCCTGGGAG AGCCGTGTCC TGAGAAGGGC CTGGGCTACA ACCCTGGGCA AGTTACTTCA 003600
003601 CCTCTGAGCC TCCGATGCTC TGTGAAATGG AAGGAATGTG CTTGCCTGTC AGGTGCAGGG AGAATTCAGT GAGATTGTGT 003680
003681 GCCTAGCACA GTGCCTGACT CCCAGTAGGT GCTCAGCAAA TGCTCCCATC CATCTGGGAG TATAGACTTA GGGTTTATCT 003760
003761 ATTTTTTTTT TTTTTTGGCT CTCTGGACTT TAAAACTCAG CATCTTCTGA ACCAGAGGCA TTTCTGATTA GCCCTTCCCT 003840
003841 ACCTATTTTC CTAGTATCAC TCTTTAATCA GCTTGGGGAG GTGGCAGCAT TTCATGGCCT CCGTAGTAAC TCACAATGCT 003920
003921 TCCTGGGGTA TTTAAATTCT ACTCTCTCAT CAGCACTGAG CACCTACTTT GGGCCCTTTC CCGTGCTAGC CATTTGGGGG 004000
004001 AAATATAGGT GAAGAGTGGC TGGGGTTTGA ACCTTTAGGA TTTCACAGCC ATGCTGGATG GGATAAAACC AGCTCACATG 004080
004081 GAGAATCAGA GAATGGGACA GTGCCACAAA ACAGTCTACT GAGGCACAAG TTCTGAGTGC CTGGGAAGTG GTAGAGAGAC 004160
004161 CCCAGAGAGG GCTGCTGCAG TCTGGAACAG CTTCCTAGCA AGCTGTACCA AACAGGGCCT TGAAGGATGA GAAAGATCTG 004240
004241 GCTGAGATGA TACCCGACCC TCTAGGGAAA TTCTTAAAGT AACTTCTAGG AAATGTCATT GCTCCTTAAA AAAAAAAAAA 004320
004321 AAAAAAAAAA AGCAGGTTCT AATTCAAATT CCGCTGCACT ACTGAAGTAG TGCAGGACTT ATCAGAACCT TTAAAATGCT 004400
004401 AATGGCAATT TCAAATACTC AGGGACAGGG CATAGGATGA AGTGTTCCTT GACTTTTATG GCCGTAGAAT CTTTTTCTCA 004480
004481 TGGAACATCG TTTAGAACTG TGGGAGATGC TAGGCTGGGG TTTCTATGGG AAAAGTACAG CAGTGATAGA AGATGGCATA 004560
004561 ATTAGGGTAC ACTTAGGTGC TTTGTAGCAT TGGCTGAAAA GGAAGCAGAC CGGGTGGGCG TGGGGGAGTC TCAACTTGGT 004640
004641 TCCAGGAGCC AGGCCAGCTT GATGCGTTTT TTTTTTTTCT AATGGTGGGA GGGCAGGCCA ATAGTTGGAG AAACTAGAGG 004720
004721 CCTGACAGTC GGTGATGGAA GAGATGTCTA CTAAGCACGG TTGTCAGATC TTTTGCGGAG AGATGCGGGT GTGCGTGTGT 004800
004801 CTGTCAGAGT GTAACAGGAT CCAGCCCTCT GGGAAGGGGC TGACCAGAAC CAGGCAGGGG GTTTCTGTCT AGGACAAGTA 004880
004881 GGGTCCATTT TCAGGGGAGC TGAAATATTT GCAGGGGGTG CTCTGAGACC CACAGCCAAT AAATAGGGAA GCAACATGCT 004960
004961 TTTGGGCAGG GTCCATGTGG TTAGGGTTGA TTTTGATGGG GCTGGGGGGC TTAGAGTTAG ACCCCCTGCC CTGGTCAGGC 005040
005041 CCCACTCCCT GGCTGGTGGG GGCGGGAGGC CTCTGAAGCT GCAGCTGGAG GGGCCGGGGC AGTGTTGCAT GGTGTGATTA 005120
005121 ACCTACTAAC CCAGGGCTCA GCCGGGACGC TGTGGCGTGT GACGAGGTGC CTGGCCTTCT GCCAACCAAC TAACCCACTA 005200
005201 ACCAGGCCCG AGCATGCCCT ACTAACCACC CCCCCGCAGC CAGATCCTAC TAACTGTGCA GCTCATGGGC CTTTCAAGGG 005280
005281 GCTGGGATAT GGGGGCAGCC AAGGCTCCAG AAGGCTCTGC CTATGGGCTG GGATCTTTGT GCAGACCCAC GTTCCAGGAC 005360
005361 AGAGAATGCA AATAAGACTC ACCAACTCTG CCACTTCCTG TTGAGTGAGT TTGAGTAAGT CACCTCACTT CTCTCAACCT 005440
005441 CAGTTTCCTC AGTGGTAGAA TGCGAGTTCT GATACCTTAC AGGTTGCAGT GAGGATTCCC GTCAATATAA GGGTCTCAGC 005520
005521 ACATGGCAGA CACCTAAAAA AAAAAAAAGT ATGAGGATGG AGGAAGGCCC CTCAAACCTG GTTGAACACG TCTGCTGCCT 005600
005601 AGGCCCTGGC CTCTCTGGGT GTTCTGCACA CAGATCCTTC TGCCTGGGGC AAGACACTTG GCTTTGAATC CATGTCACTT 005680
005681 CCCCACATTC TTCCTCCGTC TCAGCTTTCT TTTCTGTAGG CAGCTCTTTT GTTCGATTAC TAACCCGTCT AACCCCTGGG 005760
005761 GTGCCTCAAC TGCACCCCGA TCATCCCTTA ACAAACTAAC GGACCTGCGT GCGTTCTTCC TTTTCTCTTA GCGACTCCTG 005840
005841 TGTGTGTCTG CTGAGGTGCC CTGTCCGCTG GTGCTGTGCT CTGACTTACT AACCCAGCCC CTACTAACCC TGTTTTCTCT 005920
005921 TCTTACTAAC CCCAGCCCTG CCGAGCTCTG GGCTCCCCCC GGGGGCTGGT CCCCCTCCTT TTGGCAAGCA GATGACCTGG 006000
006001 GGCTACTGGC CCTGTAGACA GATGTCCCAC TTTGCTGCCC CATATTGGCT GTAAGATCAG AGTCCACTGG GCCAGGTCTA 006080
006081 AGGCAGGGGA TGGCCCTATT AACAAGACTC AGAGGAGGAA GAGGTGGTCC TGTGGATGTG GGAGGCTGGA CTCTGAGTAT 006160
006161 GACATCTCTC CTATGTGCAG AAGTCTGGTT GCCACTGGGA GTAGGTGGGA CCAGGGAAAT CTCTGGGACG TGAGTGTGGA 006240
006241 GGCCTGTTGG TCTAGACTCT AGACTGTGGA GCTCTGAGCT TTTGTGTCCT CTGGAAGGAA GCTGGGGAAG AATCCTCTCC 006320
006321 ATTGTTAAGT GACGGGGATA GAAGCTGTCC TGCACAGGAA GTCACGAGGG GGGCGTATCC CACGAGGAAG GCAGGAGGGG 006400
006401 GCGTGCCCCT CACCGGAAAT TAGCAGAGGG GCGTGTCCCA CACCGGAAGT CAGAAAGCGG AGCCTTTCTT ACACCGGAAG 006480
006481 TCAATGAAGC GGGTCTTTCC TACGCTAAAA ACCACTGAGT GGAGTATTTA GTACACAGGA AGTCGGCCAG AGAAACATTT 006560
006561 CTCATATTTG AAGGCCGGAA AGAGGGACAT TTCTGACACC GGAAGTCAGT GAGAGGACTC TTTCCCACAC AGGAAGTCAG 006640
006641 CTAGAGAGCC GTCTCCCCTC TCTGGAGCCG AGAGAGGCCG GTTTCCCCCA CCGTAAGTAG ACGTGGGGCC GTGACCGGAA 006720
006721 GTCCTTGGGA AAGATCCGTC CCATTCCCGG AAGCTAGAGG GCGTTAGTTG TCGGGTTGAA AAGGGGTGTG GGGAGGGGAA 006800
006801 GCAGCTTTAC CCCGGGCTCG GAGTTTGCAG GAGAGAGAAG TGGGGAGCAA GAAGTGAACC TCAGGGGCTC ACAGGGTTCC 006880
006881 CGCAGATGCT CAGGCCGGCC AGGAATGCAT CTCTGGCTCT CTGTTCCCAC GGACGTCACT GCCTCAGCCA GCCTCCCCCA 006960
006961 GAGCCCGCCA GCCGCTAAGC CGGGGCCACA CCTGGGGGTG ATTTCATGCC TCACCTCCAG TAGGCACCTT GGTTTCTTTG 007040
007041 GGCTAATCTC TGGCTCCCTT GCGCTAACTC TTGCTCTCAC CCAGCTAATC CCTGCCTCAC CCTGACTGCC CCAGGGGCTG 007120
007121 ACCACTAACA ACCAACCTGG CCCTGTCTGG GGGTTCCAGG CTCCTGGCCT GGCCCTGACC GGTTCTTAAT TAACCTTTCC 007200
007201 TTCACCTTGA CTAACTCCTG CCTTCCTGGT CTGTTCCTTT CAGCAGAAAC TAATGGTTTG TGGATTTTTT TCTGACTAAC 007280
007281 AACAGGTCTA ACATTCCTCG TTACTGTTAA CAGCTTGGAT GTCGGCATGG CTGGGAAGGG GCTAACACAG CTTTGAACTT 007360
007361 GGCTAACACA GGTTTGAACT TGGCTAACAC AGGTTTGAAC TTGACTAACA CAGGGAAAAG CATAGCTAAC AATTTTGGGC 007440
007441 GTGGTGGCTG CTCTGAGTCA GAACAATCAG AAGTCGGTAA AGATGGTAGT TTTCTAAAGG AGGTGCCAGG GCTCTGGTGT 007520
007521 GGACCAGGCC TGATGGAGCA GTGGTACCCA CCAAGGTGGG GTCAGAAGTA TAGCCAGTCT TGCAAGGTTT TGGCCATTGG 007600
007601 GCATATCTTC ACTCCTCATA GTCTGCATTT GGTTTCAGTT CTTAAAAAAA TATAGCCTTA TAGCTACAGT AGTTTGCACA 007680
007681 AGTAGATGCA GCTCTTATAA ACCTTAAAAT ACCTGTCTGG TGTCTACAGA GCATATGCCA TTTTGTATAG AGTCACCCTT 007760
007761 CCCCAGGCCA GGGCCTAGAG TCTTCATTTT GGGGACTTTG TGTTTTGGAA GTTCTAGGAC ATAAAGCTTT AGATCAGAGT 007840
007841 ATTCAGAAGG GTTATAACTC CGTCAGTCAT TTACATGTTA GTAGTATAAA TTATCTGAGC TTCCTGTTCT AACTTTTAGC 007920
007921 TCTTCTAGCA TAAACTCTTC TGTGCAATTT AGCTGCACCG AGGAAACGGG AGTTTTTCTG GAAGGGACTT TTGATCTCTT 008000
008001 TAGACTGAGG GAACGTCCTT TGGGAGTAGA GGGGCAGGGA GCATACGCAA GGGATTCCAG GTGCAGGTAA AAGGTGGCAC 008080
008081 TAGTTCAAGG TTTTGCTGAC TCAGTCTGGT AGTCAGAGTC TGCAGGAGAA GACAGTTCAA GGCAGGGCCT GGAGGATTGG 008160
008161 ATCAGTTTAG GGACAGGTCA AAGGCTGGCT TACAGACCTT AGAGGCAGGT TGCTTGGGTC GTTGAATGCT AGTCTGGTGC 008240
008241 TGAGAGCCCT TTTCTCTGGC AACTGTGGAC TCAGAGCTAA CCAATTGTAG TTGGCAGTGG GGGTGAAGGG TGATCCAGAG 008320
008321 GCCTGAGCTG CAGAGGGCAC AAGAGAGAAA AGATGTCTTA GAAAGAGCTT TGAGAACATG CCTTGGCTGC TGGCAGGGAC 008400
008401 CTTGGATGGG GTAGTCTACA CCCGGAAGTG CCTGCCTGCC ATCCTCTAGT GGCTGCCTTG CTCCATTTCA CTCAAAGCAG 008480
008481 GAAGCTCACA CCTCCTATTC CTGAAACTCC TCTTTGTTTA ACTGCAAAGA CTTGATGCTG CTAAGGATCT ACTATGTGCC 008560
008561 AGGCACTGCT CTGGGCGCTG GGACCTGCAC CTGGGCTTTT TCGTCATGGT GCTTTTATAG CCTAGTGGGA GAGTTGGTGA 008640
008641 AGTAGATAGT GATTCAGTGA GATGGGTGTT ATGATTGGTC AGGGGTCTGT GGGAGCACCA AGGAGACAGA CAAGATTGAT 008720
008721 GTGCACCTAC TCTGTGCCAG GCGTGTGCCA GGCATTGGGG ATGTAGTGGT AGTTAAACAC CATTTGGTCT TCAGGAGCTT 008800
008801 TAATTCTAGT GTGTTGGGTG CAGGGGGGTG GAATGGGGAC AGAGAGACAC CTAATCCACC CTGTGGTGGC TTTCTGGAGA 008880
008881 GGGAGGCATC TAAGCTGAGC TGTGGCTGGG TGGAGTGTGG GTGGGGATGA GTTCCGGGCA GCGAGAGTGG TGGACACCAG 008960
008961 TTTCTGGGGA TCAGAGAGGA TCCAAAGAGG TTCTGGAAGG TTCATGTGGA ATGTAGCAAG AGATAGGAGA CATGGACATG 009040
009041 GTGCCGGGTC TGGTTGCCAA GAAGTTTAGA TTTTATCCTT AGGCCTTGGG GAGCGACGGA TATGATCTGA GAAAGGGAGT 009120
009121 TAGTGGATTT GAGTTTTAGG CTGGCCATTT GGCTTTTCCA GCCCAGGTGG AACTCAGAGG AGTTTGCAAT GGCCTCTGGC 009200
009201 CACATTTTAG ACAACTGAGC AGAACTTTTT GAAACTAGGA AGACCCTTTG GTCCATCTTT TGATAAACAG AATCCATACA 009280
009281 TGTCTACCCC AGTTGGAAGT ATCTCTGCAA TGACTGGAAA GTAAAGAGGA CCAAGGTGAA AATAAAGGCT CGGAAGGGGA 009360
009361 GCAATCTTGA AAACATGTCA TCCCATGGTG GTGGGAAGTC CCTGGAGAAG ATCAGGGGAA ACACAGTCAT AGGCTGCAAG 009440
009441 TCTATAAGAT AATTCCATTG GGGAGGGAGC CCATTTGTCA TGCATGGCTG CAAGGGGCAG ATACAAGTGT GGAGTAAGCT 009520
009521 TGCAAGAGCT GATCCTGGTC CCAGAGAGGG AAAAATATGC CTTGGTGGGT AATGAACCTT TTGTTCCCAG AGGCAGAAGG 009600
009601 ATTGGGACTA GGCCAACATA GAGATTGGCG ATGGTTGTGA GATTCTAAGA GTGTGTGTGC ATCTTGACAA TATTAGAGGA 009680
009681 GGCTGAGCCC AAGCAGGCAC ATTCTCTTCG ACCCCTCCCT CATTCAGTCT GCTTTGGAGT CTACTGAACA TCAAGCTTGC 009760
009761 TATGAGCAGG ATCTTAGAGC TGAGGAATTG GCCTCCCAAT CCGAACAGGT GTTATAATCC TTTCTTAATA GGTTGTGCTG 009840
009841 TGGACCCAAT GTGAGGGCTG TGCTGGTGTA AATGGTGACA TGTTGAGCTG GGGGGATGCT TTCGGGGTGG GGGGACTGGT 009920
009921 TCCATTCCAT CAAAGGCCCT CTTGAGAGTC TATCCAGGGA CCCATTGTTT TACTTTAACA GACCAGAAAA GATGTTTGTT 010000
010001 TTCCATGTCA TTACCCCCAG GGGATACCGA ATGTGTGGGT AGAAATTTCT CTGTAGATTA AAAATCAGAT TTTTACATGG 010080
010081 ATTCAACAAA GGAGCGTCAC TTGGATTTTT GTTTTCATCC ATGAATGTAG CTGCTTCTGT GTAAAATGCC ATTTTGCTAT 010160
010161 TAAAAATCAA TTCACGCTGG AAAAAAAAAA AAA
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