Difference between revisions of "Lnc-CRYBA4-2:1"
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==Annotated Information== | ==Annotated Information== | ||
+ | ===Name=== | ||
+ | Gomafu | ||
+ | |||
+ | ===Characteristics=== | ||
+ | Please input characteristics information here. | ||
+ | |||
+ | ===Function=== | ||
+ | Gomafu can bind the splicing factor 1 (SF1) protein through its UACUAAC repeat sequences. This sequence is a much stronger intron branch point sequence than found in most mammalian introns. In-vitro Gomafu binding to SF1 can inhibit splicing and spliceosomal complex formation suggesting Gomafu can function to regulate splicing efficiency ([http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011))]. Regulates retinal cell fate specification [http://www.ncbi.nlm.nih.gov/pubmed/20459797 (Rapicavoli (2010))]. Variants confer susceptibility to myocardial infarction, possibly through altering the RNA's protein binding properties [http://www.ncbi.nlm.nih.gov/pubmed/17066261 (Ishii (2006))]. Probable target of transcription factor Oct4 in mESCs. Appears to maintain Oct4 expression in a feedback loop helping to maintain pluripotency [http://www.ncbi.nlm.nih.gov/pubmed/20026622 (Sheik Mohamed (2010))]. | ||
+ | |||
+ | ===Expression=== | ||
+ | Expressed predominantly in the nervous system ([http://www.ncbi.nlm.nih.gov/pubmed/17066261 Ishii (2006)], [http://www.ncbi.nlm.nih.gov/pubmed/17623775 Sone (2007)], [http://www.ncbi.nlm.nih.gov/pubmed/18184812 Mercer (2008)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]). Shows dynamic regulation during retinal development [http://www.ncbi.nlm.nih.gov/pubmed/15226823 (Blackshaw (2004))], differentiation of neural stem cells into oligodendrocytes [http://www.ncbi.nlm.nih.gov/pubmed/20137068 (Mercer (2010))] and in mouse embryonic stem cell (mESC) differentiation [http://www.ncbi.nlm.nih.gov/pubmed/20026622 (Sheik Mohamed (2010))][http://www.ncbi.nlm.nih.gov/pubmed/18562676 (Dinger (2008))]. Expressed in the nucleus accumbens of normal human brains and one of a few genes up-regulated in this brain region in both cocaine and heroin abusers ([http://www.ncbi.nlm.nih.gov/pubmed/16710320 Albertson (2006)], [http://www.ncbi.nlm.nih.gov/pubmed/21128942 Michelhaugh (2010)]). Nuclear specific localisation to novel nuclear matrix subdomain [http://www.ncbi.nlm.nih.gov/pubmed/17623775 (Sone (2007))]. | ||
+ | |||
+ | ===Conservation=== | ||
+ | Well conserved in placental mammals, present in chicken and appears to be conserved back to amphibians ([http://www.ncbi.nlm.nih.gov/pubmed/20459797 Rapicavoli (2010)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]). Outside of mammals sequence conservation is low but the SF1 binding UACUAAC repeats are conserved ([http://www.ncbi.nlm.nih.gov/pubmed/20459797 Rapicavoli (2010)], [http://www.ncbi.nlm.nih.gov/pubmed/21463453 Tsuiji (2011)]). | ||
+ | |||
+ | ===Misc=== | ||
+ | Please input misc information here. | ||
+ | |||
===Transcriptomic Nomeclature=== | ===Transcriptomic Nomeclature=== | ||
Please input transcriptomic nomeclature information here. | Please input transcriptomic nomeclature information here. | ||
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===Regulation=== | ===Regulation=== | ||
Please input regulation information here. | Please input regulation information here. | ||
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===Allelic Information and Variation=== | ===Allelic Information and Variation=== | ||
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[[Category:Intergenic]] | [[Category:Intergenic]] | ||
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Revision as of 08:02, 9 October 2014
Please input one-sentence summary here.
Contents
Annotated Information
Name
Gomafu
Characteristics
Please input characteristics information here.
Function
Gomafu can bind the splicing factor 1 (SF1) protein through its UACUAAC repeat sequences. This sequence is a much stronger intron branch point sequence than found in most mammalian introns. In-vitro Gomafu binding to SF1 can inhibit splicing and spliceosomal complex formation suggesting Gomafu can function to regulate splicing efficiency (Tsuiji (2011)). Regulates retinal cell fate specification (Rapicavoli (2010)). Variants confer susceptibility to myocardial infarction, possibly through altering the RNA's protein binding properties (Ishii (2006)). Probable target of transcription factor Oct4 in mESCs. Appears to maintain Oct4 expression in a feedback loop helping to maintain pluripotency (Sheik Mohamed (2010)).
Expression
Expressed predominantly in the nervous system (Ishii (2006), Sone (2007), Mercer (2008), Tsuiji (2011)). Shows dynamic regulation during retinal development (Blackshaw (2004)), differentiation of neural stem cells into oligodendrocytes (Mercer (2010)) and in mouse embryonic stem cell (mESC) differentiation (Sheik Mohamed (2010))(Dinger (2008)). Expressed in the nucleus accumbens of normal human brains and one of a few genes up-regulated in this brain region in both cocaine and heroin abusers (Albertson (2006), Michelhaugh (2010)). Nuclear specific localisation to novel nuclear matrix subdomain (Sone (2007)).
Conservation
Well conserved in placental mammals, present in chicken and appears to be conserved back to amphibians (Rapicavoli (2010), Tsuiji (2011)). Outside of mammals sequence conservation is low but the SF1 binding UACUAAC repeats are conserved (Rapicavoli (2010), Tsuiji (2011)).
Misc
Please input misc information here.
Transcriptomic Nomeclature
Please input transcriptomic nomeclature information here.
Regulation
Please input regulation information here.
Allelic Information and Variation
Please input allelic information and variation information here.
Evolution
Please input evolution information here.
You can also add sub-section(s) at will.
Labs working on this lncRNA
Please input related labs here.
References
Please input cited references here.
Basic Information
Transcript ID |
lnc-CRYBA4-2:1 |
Source |
LNCipedia2.1 |
Same with |
, |
Classification |
intergenic |
Length |
10193 nt |
Genomic location |
chr22+:27042391..27072440 |
Exon number |
, |
Exons |
, |
Genome context |
|
Sequence |
000001 CAGCTACAAA GACGACGCCG GCTGCGCTCG CGGGACCAGA GGGAGGGAGG CTGCGGACGA GTGCGGGGAG GAGTTTGAGA 000080
000081 TGGGAGGCGC TTGCAGGGGC TCCCCCAGTT CTGCGCTGTG AGCCGGGGCA CAAAGAGCCC TCTGCACTAG CGCCGCAGGA 000160 000161 CCGCGGACCC GAGTTGGAGG CATCTGTCCA CCCATGTGGT TCCAGACACG TTCATGTGGC CACCATGACC CCGTCGGCAT 000240 000241 CACAGGGGTA ACCAAGGTCC ACAGAACGAG GGGAAAGGGT CACTGTGGAT CAAGCCAGGC TCCTCTGAGC AGTCCAGGGT 000320 000321 CTATTTACAG AGAGCAGCAA GTTCCTGGGA CAGAGGAGAC AGAAGGGAAT TTCCAGGTTC TTCAGGACGT TCACAACCAC 000400 000401 ACTGAGAAGC ATCTTTGCAG ATAAGTATTT AAACTTACCA GCCCATAGCC TACCAGCCTG CCCTCTTCTG GTCTGTGCAG 000480 000481 GAAAGTGTAG TATCCTAGAA TGCCAAAGTG GGAGGGGAAA TGGGTGATGT AGCTCATTCT CTTTTCTACC TCTATGGAAG 000560 000561 AAAGAAAGAG CCTGTCCCCA TTTTGTGGGG TCCCAGAAAG GGTGATTTTC ACACTTCACA TTTGGCGTTA GGGCTAGTAT 000640 000641 TTCACAAACA TTACCGTCTG GAACTTTTGA AGGCTGAGTT AAATGACTTC ATCTTGTGTA CTTGTAGAAC TGCTATTAGA 000720 000721 AGGAGGCTGG GGACTCCCTG ATGATGTGAA CCAGCCCTTC TCTTCTCAGT TTCAGCACTT TGTGATCATA TTTATAAACC 000800 000801 TTGGACAGGG CTCCTTGGCC TTAGAGTTAA GTGAAGAGTT AACACTGTGA CTTTAGATGC ATTTTTCTCA GTGTAAGTGT 000880 000881 CTGAGCTCAT CTCCAGTTCT GGACTCGTGC CCCCACTCCC GGGTGCTGAC AGCAAGCTCT GAAGATATGC TGAGAGAGCT 000960 000961 CCCTGACTCT CCTGACTCAG GTCTGCCAGT TGATGAAGAC AGCACAGTTG TTACCAAAAA CAAAACCTGG CAGATGGTCC 001040 001041 TAGGTCAGGA TTAGTGGTCA TTCTCTGGTC TTCTCCAGAC TGGTGACACA GGGTGGTCTT AAAAGAGTCC TAGTCCAGCC 001120 001121 TCTGGCTCCC CGAATTTCCT CTGGTGCATG GGGCATCAGG AAAGGGCAGG GGAGAAGGAG GGGGAGCAGA AAAATAACTG 001200 001201 AGGCTGGGCA GAAGGGTCCC TTCCATTTCC CATCCATTGC TTCAAACAAT GGGTGATTAC CGTGCACCTT GAGTGAATGT 001280 001281 CAAGGCAGGA AGGGTTCCAG GGCCACCCAG TGTGGCAGGA GCAGAGCTGG GATCAGAATT CTGGATTCCT GACTCTCCGT 001360 001361 TCAGCTGCTA TTCAGCTATC ACCAAGCTGC TGAGTTTGTC CTACTTTCTC CTGGGTCACA TTCTGCTGTT GTTGGGAAAC 001440 001441 AGGGAGTGAG TGAAGGGAAC CTGGGAACCC TTCTCCCCTC ACCTTTTAAG GATGTTCTGG GGTGGAATAA AGAGAGGTGG 001520 001521 AGGGTGGGGT GCCTGGCCCA GCCTCCCTGG CTCCTGGTCC TTCTTTCTTC AGCAGGGAGT TCTGGCAAGG CCTGGGCCTG 001600 001601 GGGAGGGGGC CTGGGTGCAG TTTTCTCCTG CGGTGTGGTT GGCTCTTTTG TCTTCCAGGA TGGGCCTGTG GGGTCTGTGT 001680 001681 GGGGAAGGAA GGAGCTGGGA GCCTGGGCTG CCTGTGTGTC GGCTGGATGC TGCCAGCACC GGCATGGACC AAGCAACTTC 001760 001761 TCTGAGCCAG ATGCTGGGGA CGCAGAGGTG AACCCAGAGA CATGATCCCA TCTGCTCAGA TCTTCATGTC AGAACACGCT 001840 001841 TTATTACAGT CTCGGCAAGG GGGTGGCTCC ATCTGGGCCG CATCTCCAGG ACTCCTGGCC TGGACTTCTC TTTGGACCTC 001920 001921 GGGTGACCTT GGATTCTGGC CACAGTGACT TAGCGGTCAG ACTCCGGTGG TTTTCTAGCC CGCTGGGTGA CTCCCTGAAG 002000 002001 ATCTCATCCT CTTCACACCT GTTGGGATGG AGCCTCCCAT GGATAGGAAC TCTTCCTGGT TGATGCTCAG CAGATGACTG 002080 002081 ATCTGGCTCT GGAGGACAGC TCCAGGGGTA TGAGGGAGGC CTGGCAGCCC ACTACTCCCT CCTCACCTGC TCGGGCCCTG 002160 002161 CCTGCTGGGC CCTATTGTCT GGGTCTGGGG GCCCTTTCCT GCCCCATGTG AACTTGATTC CTCCTCGCGT TTCTGCCGGT 002240 002241 GACCAGACAG AGCCTGGCCT GGGCCAAGTC CCCACTGACC ACACTTTCCC CAAGGCTGGG TCTCAAAGGA CCCTACAGGA 002320 002321 TGGGGACAGG AACAAGGATG GGAGTCGGGG AGGGGCTGTC AGGCAGAGGG CAGATGCAGC TCCTCGGGTG CCGCTGGCTG 002400 002401 GAGTCCTTTG TCTCCATTTG CTCAGTGCGT AATTGTCATT TTGTGGGGGA CTTCCTTGGT GGGGCTTTTC CATGCTTTTC 002480 002481 CTCTCCCTGA TGGTTACAAA GAGGAGACAG TCAGGATCTG GGAGGAGCTG GAGCCTTCCC CCTGTGCTGT TGAACTCTGG 002560 002561 GAGGGGCAGC CAGAGGGGCT GAGAGTGCAC CATCCTGAAA AGAGAGGGTC TTTAAGAGAT AAGATTTAGG CTAGGGAAAT 002640 002641 TCACTAGAAA GAGACAGGTG GCCCTGGGTT TTTTTTCCTG CCATCCAAAG GGAACCAGTC TTACCCAAAG GCTTAAGGGG 002720 002721 TCACCTTAGC CCAGTCTCAG GACACTCTTC TCCAATCAGA TCGCTGCTTC TAGTTGCACT GCTCCTGGAT TCTGTTCTTG 002800 002801 GGGAACAGAA GGTGGCAGGA CAGGCCCCAC AATCTGCAAT TCCAGCTCCC TCCAGAGGAG ACAGTCCCAG CGTTTGCAAG 002880 002881 AGAGCAGCTT GTGGCCTCCC TTAGGCAAGT TTAAAAGCCA GATGTCCTTT TTCCCAGAAT GCGGAGTGGT GTGTACTATT 002960 002961 CATCAGCTTG GGCTGCCACA GCACCATGCC AGACTGGATG GCTTAAACAT CAGGAATTTA TTTTCTGCCA GTTCTGGAGG 003040 003041 CTGGAAAGTC CAGATCAAGG TGTTAAGACT TGGTTTCTGG TGAGGCCTCT CTCCTTGGCT TGCAGGTGGC ACCTTCTCAC 003120 003121 TATGTCCTCA CATGGCCTTT TCTCTGTGGA GAGGGACAGA GAGCATGAGC AGGCTCTGGT GTCTCCTCCT CTTCTTATAA 003200 003201 AGACACTAAT ATCACCATAT TAGGGCTTAA ACCTATGACC TCATTTAACC TTAACCCCTT AAAGGTCCCA TCTCCAAAAA 003280 003281 CAGTCACATA GCAGGCTACT GCTTCAACAT ATGCATTTGG GGGAGGGGAC ACCATTCAGT TCTTAACAGG GTGGTCACCG 003360 003361 CAAACATGGA AAGTCAGAGC CTTCTCCCCT TCAGAATTCC CGCCCCCACC CAGGGATGGG GAGGAGGAGC AGAGAGGTAT 003440 003441 GGGAAGCAGA CACGGAGAGT GGCAGGTACC ATGCTGGGGT GGCTCAGGAG TGCTTCGGAG GACATATGGA ACTGGCAGGG 003520 003521 CTCAGTGCAG GGAGGCGGAG GCCCTGGGAG AGCCGTGTCC TGAGAAGGGC CTGGGCTACA ACCCTGGGCA AGTTACTTCA 003600 003601 CCTCTGAGCC TCCGATGCTC TGTGAAATGG AAGGAATGTG CTTGCCTGTC AGGTGCAGGG AGAATTCAGT GAGATTGTGT 003680 003681 GCCTAGCACA GTGCCTGACT CCCAGTAGGT GCTCAGCAAA TGCTCCCATC CATCTGGGAG TATAGACTTA GGGTTTATCT 003760 003761 ATTTTTTTTT TTTTTTGGCT CTCTGGACTT TAAAACTCAG CATCTTCTGA ACCAGAGGCA TTTCTGATTA GCCCTTCCCT 003840 003841 ACCTATTTTC CTAGTATCAC TCTTTAATCA GCTTGGGGAG GTGGCAGCAT TTCATGGCCT CCGTAGTAAC TCACAATGCT 003920 003921 TCCTGGGGTA TTTAAATTCT ACTCTCTCAT CAGCACTGAG CACCTACTTT GGGCCCTTTC CCGTGCTAGC CATTTGGGGG 004000 004001 AAATATAGGT GAAGAGTGGC TGGGGTTTGA ACCTTTAGGA TTTCACAGCC ATGCTGGATG GGATAAAACC AGCTCACATG 004080 004081 GAGAATCAGA GAATGGGACA GTGCCACAAA ACAGTCTACT GAGGCACAAG TTCTGAGTGC CTGGGAAGTG GTAGAGAGAC 004160 004161 CCCAGAGAGG GCTGCTGCAG TCTGGAACAG CTTCCTAGCA AGCTGTACCA AACAGGGCCT TGAAGGATGA GAAAGATCTG 004240 004241 GCTGAGATGA TACCCGACCC TCTAGGGAAA TTCTTAAAGT AACTTCTAGG AAATGTCATT GCTCCTTAAA AAAAAAAAAA 004320 004321 AAAAAAAAAA AGCAGGTTCT AATTCAAATT CCGCTGCACT ACTGAAGTAG TGCAGGACTT ATCAGAACCT TTAAAATGCT 004400 004401 AATGGCAATT TCAAATACTC AGGGACAGGG CATAGGATGA AGTGTTCCTT GACTTTTATG GCCGTAGAAT CTTTTTCTCA 004480 004481 TGGAACATCG TTTAGAACTG TGGGAGATGC TAGGCTGGGG TTTCTATGGG AAAAGTACAG CAGTGATAGA AGATGGCATA 004560 004561 ATTAGGGTAC ACTTAGGTGC TTTGTAGCAT TGGCTGAAAA GGAAGCAGAC CGGGTGGGCG TGGGGGAGTC TCAACTTGGT 004640 004641 TCCAGGAGCC AGGCCAGCTT GATGCGTTTT TTTTTTTTCT AATGGTGGGA GGGCAGGCCA ATAGTTGGAG AAACTAGAGG 004720 004721 CCTGACAGTC GGTGATGGAA GAGATGTCTA CTAAGCACGG TTGTCAGATC TTTTGCGGAG AGATGCGGGT GTGCGTGTGT 004800 004801 CTGTCAGAGT GTAACAGGAT CCAGCCCTCT GGGAAGGGGC TGACCAGAAC CAGGCAGGGG GTTTCTGTCT AGGACAAGTA 004880 004881 GGGTCCATTT TCAGGGGAGC TGAAATATTT GCAGGGGGTG CTCTGAGACC CACAGCCAAT AAATAGGGAA GCAACATGCT 004960 004961 TTTGGGCAGG GTCCATGTGG TTAGGGTTGA TTTTGATGGG GCTGGGGGGC TTAGAGTTAG ACCCCCTGCC CTGGTCAGGC 005040 005041 CCCACTCCCT GGCTGGTGGG GGCGGGAGGC CTCTGAAGCT GCAGCTGGAG GGGCCGGGGC AGTGTTGCAT GGTGTGATTA 005120 005121 ACCTACTAAC CCAGGGCTCA GCCGGGACGC TGTGGCGTGT GACGAGGTGC CTGGCCTTCT GCCAACCAAC TAACCCACTA 005200 005201 ACCAGGCCCG AGCATGCCCT ACTAACCACC CCCCCGCAGC CAGATCCTAC TAACTGTGCA GCTCATGGGC CTTTCAAGGG 005280 005281 GCTGGGATAT GGGGGCAGCC AAGGCTCCAG AAGGCTCTGC CTATGGGCTG GGATCTTTGT GCAGACCCAC GTTCCAGGAC 005360 005361 AGAGAATGCA AATAAGACTC ACCAACTCTG CCACTTCCTG TTGAGTGAGT TTGAGTAAGT CACCTCACTT CTCTCAACCT 005440 005441 CAGTTTCCTC AGTGGTAGAA TGCGAGTTCT GATACCTTAC AGGTTGCAGT GAGGATTCCC GTCAATATAA GGGTCTCAGC 005520 005521 ACATGGCAGA CACCTAAAAA AAAAAAAAGT ATGAGGATGG AGGAAGGCCC CTCAAACCTG GTTGAACACG TCTGCTGCCT 005600 005601 AGGCCCTGGC CTCTCTGGGT GTTCTGCACA CAGATCCTTC TGCCTGGGGC AAGACACTTG GCTTTGAATC CATGTCACTT 005680 005681 CCCCACATTC TTCCTCCGTC TCAGCTTTCT TTTCTGTAGG CAGCTCTTTT GTTCGATTAC TAACCCGTCT AACCCCTGGG 005760 005761 GTGCCTCAAC TGCACCCCGA TCATCCCTTA ACAAACTAAC GGACCTGCGT GCGTTCTTCC TTTTCTCTTA GCGACTCCTG 005840 005841 TGTGTGTCTG CTGAGGTGCC CTGTCCGCTG GTGCTGTGCT CTGACTTACT AACCCAGCCC CTACTAACCC TGTTTTCTCT 005920 005921 TCTTACTAAC CCCAGCCCTG CCGAGCTCTG GGCTCCCCCC GGGGGCTGGT CCCCCTCCTT TTGGCAAGCA GATGACCTGG 006000 006001 GGCTACTGGC CCTGTAGACA GATGTCCCAC TTTGCTGCCC CATATTGGCT GTAAGATCAG AGTCCACTGG GCCAGGTCTA 006080 006081 AGGCAGGGGA TGGCCCTATT AACAAGACTC AGAGGAGGAA GAGGTGGTCC TGTGGATGTG GGAGGCTGGA CTCTGAGTAT 006160 006161 GACATCTCTC CTATGTGCAG AAGTCTGGTT GCCACTGGGA GTAGGTGGGA CCAGGGAAAT CTCTGGGACG TGAGTGTGGA 006240 006241 GGCCTGTTGG TCTAGACTCT AGACTGTGGA GCTCTGAGCT TTTGTGTCCT CTGGAAGGAA GCTGGGGAAG AATCCTCTCC 006320 006321 ATTGTTAAGT GACGGGGATA GAAGCTGTCC TGCACAGGAA GTCACGAGGG GGGCGTATCC CACGAGGAAG GCAGGAGGGG 006400 006401 GCGTGCCCCT CACCGGAAAT TAGCAGAGGG GCGTGTCCCA CACCGGAAGT CAGAAAGCGG AGCCTTTCTT ACACCGGAAG 006480 006481 TCAATGAAGC GGGTCTTTCC TACGCTAAAA ACCACTGAGT GGAGTATTTA GTACACAGGA AGTCGGCCAG AGAAACATTT 006560 006561 CTCATATTTG AAGGCCGGAA AGAGGGACAT TTCTGACACC GGAAGTCAGT GAGAGGACTC TTTCCCACAC AGGAAGTCAG 006640 006641 CTAGAGAGCC GTCTCCCCTC TCTGGAGCCG AGAGAGGCCG GTTTCCCCCA CCGTAAGTAG ACGTGGGGCC GTGACCGGAA 006720 006721 GTCCTTGGGA AAGATCCGTC CCATTCCCGG AAGCTAGAGG GCGTTAGTTG TCGGGTTGAA AAGGGGTGTG GGGAGGGGAA 006800 006801 GCAGCTTTAC CCCGGGCTCG GAGTTTGCAG GAGAGAGAAG TGGGGAGCAA GAAGTGAACC TCAGGGGCTC ACAGGGTTCC 006880 006881 CGCAGATGCT CAGGCCGGCC AGGAATGCAT CTCTGGCTCT CTGTTCCCAC GGACGTCACT GCCTCAGCCA GCCTCCCCCA 006960 006961 GAGCCCGCCA GCCGCTAAGC CGGGGCCACA CCTGGGGGTG ATTTCATGCC TCACCTCCAG TAGGCACCTT GGTTTCTTTG 007040 007041 GGCTAATCTC TGGCTCCCTT GCGCTAACTC TTGCTCTCAC CCAGCTAATC CCTGCCTCAC CCTGACTGCC CCAGGGGCTG 007120 007121 ACCACTAACA ACCAACCTGG CCCTGTCTGG GGGTTCCAGG CTCCTGGCCT GGCCCTGACC GGTTCTTAAT TAACCTTTCC 007200 007201 TTCACCTTGA CTAACTCCTG CCTTCCTGGT CTGTTCCTTT CAGCAGAAAC TAATGGTTTG TGGATTTTTT TCTGACTAAC 007280 007281 AACAGGTCTA ACATTCCTCG TTACTGTTAA CAGCTTGGAT GTCGGCATGG CTGGGAAGGG GCTAACACAG CTTTGAACTT 007360 007361 GGCTAACACA GGTTTGAACT TGGCTAACAC AGGTTTGAAC TTGACTAACA CAGGGAAAAG CATAGCTAAC AATTTTGGGC 007440 007441 GTGGTGGCTG CTCTGAGTCA GAACAATCAG AAGTCGGTAA AGATGGTAGT TTTCTAAAGG AGGTGCCAGG GCTCTGGTGT 007520 007521 GGACCAGGCC TGATGGAGCA GTGGTACCCA CCAAGGTGGG GTCAGAAGTA TAGCCAGTCT TGCAAGGTTT TGGCCATTGG 007600 007601 GCATATCTTC ACTCCTCATA GTCTGCATTT GGTTTCAGTT CTTAAAAAAA TATAGCCTTA TAGCTACAGT AGTTTGCACA 007680 007681 AGTAGATGCA GCTCTTATAA ACCTTAAAAT ACCTGTCTGG TGTCTACAGA GCATATGCCA TTTTGTATAG AGTCACCCTT 007760 007761 CCCCAGGCCA GGGCCTAGAG TCTTCATTTT GGGGACTTTG TGTTTTGGAA GTTCTAGGAC ATAAAGCTTT AGATCAGAGT 007840 007841 ATTCAGAAGG GTTATAACTC CGTCAGTCAT TTACATGTTA GTAGTATAAA TTATCTGAGC TTCCTGTTCT AACTTTTAGC 007920 007921 TCTTCTAGCA TAAACTCTTC TGTGCAATTT AGCTGCACCG AGGAAACGGG AGTTTTTCTG GAAGGGACTT TTGATCTCTT 008000 008001 TAGACTGAGG GAACGTCCTT TGGGAGTAGA GGGGCAGGGA GCATACGCAA GGGATTCCAG GTGCAGGTAA AAGGTGGCAC 008080 008081 TAGTTCAAGG TTTTGCTGAC TCAGTCTGGT AGTCAGAGTC TGCAGGAGAA GACAGTTCAA GGCAGGGCCT GGAGGATTGG 008160 008161 ATCAGTTTAG GGACAGGTCA AAGGCTGGCT TACAGACCTT AGAGGCAGGT TGCTTGGGTC GTTGAATGCT AGTCTGGTGC 008240 008241 TGAGAGCCCT TTTCTCTGGC AACTGTGGAC TCAGAGCTAA CCAATTGTAG TTGGCAGTGG GGGTGAAGGG TGATCCAGAG 008320 008321 GCCTGAGCTG CAGAGGGCAC AAGAGAGAAA AGATGTCTTA GAAAGAGCTT TGAGAACATG CCTTGGCTGC TGGCAGGGAC 008400 008401 CTTGGATGGG GTAGTCTACA CCCGGAAGTG CCTGCCTGCC ATCCTCTAGT GGCTGCCTTG CTCCATTTCA CTCAAAGCAG 008480 008481 GAAGCTCACA CCTCCTATTC CTGAAACTCC TCTTTGTTTA ACTGCAAAGA CTTGATGCTG CTAAGGATCT ACTATGTGCC 008560 008561 AGGCACTGCT CTGGGCGCTG GGACCTGCAC CTGGGCTTTT TCGTCATGGT GCTTTTATAG CCTAGTGGGA GAGTTGGTGA 008640 008641 AGTAGATAGT GATTCAGTGA GATGGGTGTT ATGATTGGTC AGGGGTCTGT GGGAGCACCA AGGAGACAGA CAAGATTGAT 008720 008721 GTGCACCTAC TCTGTGCCAG GCGTGTGCCA GGCATTGGGG ATGTAGTGGT AGTTAAACAC CATTTGGTCT TCAGGAGCTT 008800 008801 TAATTCTAGT GTGTTGGGTG CAGGGGGGTG GAATGGGGAC AGAGAGACAC CTAATCCACC CTGTGGTGGC TTTCTGGAGA 008880 008881 GGGAGGCATC TAAGCTGAGC TGTGGCTGGG TGGAGTGTGG GTGGGGATGA GTTCCGGGCA GCGAGAGTGG TGGACACCAG 008960 008961 TTTCTGGGGA TCAGAGAGGA TCCAAAGAGG TTCTGGAAGG TTCATGTGGA ATGTAGCAAG AGATAGGAGA CATGGACATG 009040 009041 GTGCCGGGTC TGGTTGCCAA GAAGTTTAGA TTTTATCCTT AGGCCTTGGG GAGCGACGGA TATGATCTGA GAAAGGGAGT 009120 009121 TAGTGGATTT GAGTTTTAGG CTGGCCATTT GGCTTTTCCA GCCCAGGTGG AACTCAGAGG AGTTTGCAAT GGCCTCTGGC 009200 009201 CACATTTTAG ACAACTGAGC AGAACTTTTT GAAACTAGGA AGACCCTTTG GTCCATCTTT TGATAAACAG AATCCATACA 009280 009281 TGTCTACCCC AGTTGGAAGT ATCTCTGCAA TGACTGGAAA GTAAAGAGGA CCAAGGTGAA AATAAAGGCT CGGAAGGGGA 009360 009361 GCAATCTTGA AAACATGTCA TCCCATGGTG GTGGGAAGTC CCTGGAGAAG ATCAGGGGAA ACACAGTCAT AGGCTGCAAG 009440 009441 TCTATAAGAT AATTCCATTG GGGAGGGAGC CCATTTGTCA TGCATGGCTG CAAGGGGCAG ATACAAGTGT GGAGTAAGCT 009520 009521 TGCAAGAGCT GATCCTGGTC CCAGAGAGGG AAAAATATGC CTTGGTGGGT AATGAACCTT TTGTTCCCAG AGGCAGAAGG 009600 009601 ATTGGGACTA GGCCAACATA GAGATTGGCG ATGGTTGTGA GATTCTAAGA GTGTGTGTGC ATCTTGACAA TATTAGAGGA 009680 009681 GGCTGAGCCC AAGCAGGCAC ATTCTCTTCG ACCCCTCCCT CATTCAGTCT GCTTTGGAGT CTACTGAACA TCAAGCTTGC 009760 009761 TATGAGCAGG ATCTTAGAGC TGAGGAATTG GCCTCCCAAT CCGAACAGGT GTTATAATCC TTTCTTAATA GGTTGTGCTG 009840 009841 TGGACCCAAT GTGAGGGCTG TGCTGGTGTA AATGGTGACA TGTTGAGCTG GGGGGATGCT TTCGGGGTGG GGGGACTGGT 009920 009921 TCCATTCCAT CAAAGGCCCT CTTGAGAGTC TATCCAGGGA CCCATTGTTT TACTTTAACA GACCAGAAAA GATGTTTGTT 010000 010001 TTCCATGTCA TTACCCCCAG GGGATACCGA ATGTGTGGGT AGAAATTTCT CTGTAGATTA AAAATCAGAT TTTTACATGG 010080 010081 ATTCAACAAA GGAGCGTCAC TTGGATTTTT GTTTTCATCC ATGAATGTAG CTGCTTCTGT GTAAAATGCC ATTTTGCTAT 010160 010161 TAAAAATCAA TTCACGCTGG AAAAAAAAAA AAA |