Difference between revisions of "NONHSAT076153"
Line 2: | Line 2: | ||
==Annotated Information== | ==Annotated Information== | ||
+ | ===Name=== | ||
+ | PCGEM1: Prostate-specific transcript 1 | ||
+ | |||
+ | ===Characteristics=== | ||
+ | 1603 nt, 3 exons. | ||
+ | |||
+ | ===Function=== | ||
+ | Over-expression leads to inhibition of apoptosis induced by doxorubicin ([http://www.ncbi.nlm.nih.gov/pubmed/16569192 Fu 2006]). | ||
+ | |||
+ | ===Expression=== | ||
+ | Prostate tissue-specific and prostate cancer-associated ([http://www.ncbi.nlm.nih.gov/pubmed/11050243 Srikantan 2000]). Cholesterols upregulate the expression of PCGEM1 even in androgen-insensitive prostate cancer cell lines while phytosterols reverse this effect ([http://www.ncbi.nlm.nih.gov/pubmed/19186008 Ifere 2009]). PCGEM1 overexpression in LNCaP and in NIH3T3 cells promotes cell proliferation and a dramatic increase in colony formation, suggesting a biological role of PCGEM1 in cell growth regulation ([http://www.ncbi.nlm.nih.gov/pubmed/14724589 Petrovics 2004]). Low specificity as a biomarker for prostate cancer (14%) ([http://www.ncbi.nlm.nih.gov/pubmed/16515751 Bialkowska-Hobrzanska 2006]). | ||
+ | |||
+ | ===Conservation=== | ||
+ | Please input conservation information here. | ||
+ | |||
+ | ===Misc=== | ||
+ | GWAS association with schizophrenia. PCGEM1 polymorphisms may contribute to PCa risk in Chinese men ([http://www.ncbi.nlm.nih.gov/pubmed/23459097 Xue 2013]) | ||
+ | |||
===Transcriptomic Nomeclature=== | ===Transcriptomic Nomeclature=== | ||
Please input transcriptomic nomeclature information here. | Please input transcriptomic nomeclature information here. | ||
− | |||
− | |||
− | |||
===Regulation=== | ===Regulation=== | ||
Please input regulation information here. | Please input regulation information here. | ||
− | |||
− | |||
− | |||
===Allelic Information and Variation=== | ===Allelic Information and Variation=== |
Revision as of 03:30, 10 October 2014
Please input one-sentence summary here.
Contents
Annotated Information
Name
PCGEM1: Prostate-specific transcript 1
Characteristics
1603 nt, 3 exons.
Function
Over-expression leads to inhibition of apoptosis induced by doxorubicin (Fu 2006).
Expression
Prostate tissue-specific and prostate cancer-associated (Srikantan 2000). Cholesterols upregulate the expression of PCGEM1 even in androgen-insensitive prostate cancer cell lines while phytosterols reverse this effect (Ifere 2009). PCGEM1 overexpression in LNCaP and in NIH3T3 cells promotes cell proliferation and a dramatic increase in colony formation, suggesting a biological role of PCGEM1 in cell growth regulation (Petrovics 2004). Low specificity as a biomarker for prostate cancer (14%) (Bialkowska-Hobrzanska 2006).
Conservation
Please input conservation information here.
Misc
GWAS association with schizophrenia. PCGEM1 polymorphisms may contribute to PCa risk in Chinese men (Xue 2013)
Transcriptomic Nomeclature
Please input transcriptomic nomeclature information here.
Regulation
Please input regulation information here.
Allelic Information and Variation
Please input allelic information and variation information here.
Evolution
Please input evolution information here.
You can also add sub-section(s) at will.
Labs working on this lncRNA
Please input related labs here.
References
Please input cited references here.
Basic Information
Transcript ID |
NONHSAT076153 |
Source |
NONCODE4.0 |
Same with |
, |
Classification |
intergenic |
Length |
1603 nt |
Genomic location |
chr2+:193614571..193641625 |
Exon number |
3 |
Exons |
193614571..193614754,193615515..193615598,193640304..193641625 |
Genome context |
|
Sequence |
000001 aaggcactct ggcacccagt tttggaactg cagttttaaa agtcataaat tgaatgaaaa tgatagcaaa ggtggaggtt 000080
000081 tttaaagagc tatttatagg tccctggaca gcatcttttt tcaattaggc agcaaccttt ttgccctatg ccgtaacctg 000160 000161 tgtctgcaac ttcctctaat tgggaaatag ttaagcagat tcatagagct gaatgataaa attgtactac gagatgcact 000240 000241 gggactcaac gtgaccttat caagtgagca ggcttggtgc atttgacact tcatgatatc agccaaagtg gaactaaaaa 000320 000321 cagctcctgg aagaggacta tgacatcatc aggttgggag tctccaggga cagcggaccc tttggaaaag gactagaaag 000400 000401 tgtgaaatct attagtcttc gatatgaaat tctctgtctc tgtaaaagca tttcatattt acaagacaca ggcctactcc 000480 000481 tagggcagca aaaagtggca acaggcaagc agagggaaaa gagatcatga ggcatttcag agtgcactgt cttttcatat 000560 000561 atttctcaat gccgtatgtt tggttttatt ttggccaagc ataacaatct gctcaagaaa aaaaaatctg gagaaaacaa 000640 000641 aggtgccttt gccaatgtta tgtttctttt tgacaagccc tgagatttct gaggggaatt cacataaatg ggatcaggtc 000720 000721 attcatttac gttgtgtgca aatatgattt aaagatacaa cctttgcaga gagcatgctt tcctaagggt aggcacgtgg 000800 000801 aggactaagg gtaaagcatt cttcaagatc agttaatcaa gaaaggtgct ctttgcattc tgaaatgccc ttgttgcaaa 000880 000881 tattggttat attgattaaa tttacactta atggaaacaa cctttaactt acagatgaac aaacccacaa aagcaaaaaa 000960 000961 tcaaaagccc tacctatgat ttcatatttt ctgtgtaact ggattaaagg attcctgctt gcttttgggc ataaatgata 001040 001041 atggaatatt tccaggtatt gtttaaaatg agggcccatc tacaaattct tagcaatact ttggataatt ctaaaattca 001120 001121 gctggacatt gtctaattgt tttttatata catctttgct agaatttcaa attttaagta tgtgaattta gttaattagc 001200 001201 tgtgctgatc aattcaaaaa cattactttc ctaaatttta gactatgaag gtcataaatt caacaaatat atctacacat 001280 001281 acaattatag attgtttttc attataatgt cttcatctta acagaattgt ctttgtgatt gtttttagaa aactgagagt 001360 001361 tttaattcat aattacttga tcaaaaaatt gtgggaacaa tccagcatta attgtatgtg attgttttta tgtacataag 001440 001441 gagtcttaag cttggtgcct tgaagtcttt tgtacttagt cccatgttta aaattactac tttatatcta aagcatttat 001520 001521 gtttttcaat tcaatttaca tgatgctaat tatggcaatt ataacaaata ttaaagattt cgaaatagaa aaaaaaaaaa 001600 001601 aaa |
Annotation (From lncRNAdb)
Section | Description |
---|---|
ID | PCGEM1 |
Characteristics | 1643 nt. |
Expression | Prostate tissue-specific and prostate cancer-associated. |
Function | Over-expression leads to inhibition of apoptosis induced by doxorubicin. |
Conservation | N/A |
Misc | N/A |
Name | Prostate-specific transcript 1 (PCGEM1) |