DM1-AS
Contents
Annotated Information
Name
DM1-AS:DM1 locus antisense RNA
Characteristics
DM1-AS spans >6 kb, contains alternative transcription start sites and uses alternative polyadenylation sites up- and downstream of the (CAG)n repeat. [1]
Cellular Localization
DM1-AS transcripts are present in the nucleus and in the cytoplasm.[1]
Expression
The DM1-AS transcript is a low-abundance RNA[1].
DM1-AS expression appears upregulated in patients, but transcript abundance remains very low in some tissues. In addition, DM1-AS expression was lowest in brain and highest in kidney, testis and muscle.[1]
Diseases
Myotonic dystrophy type 1[1]
Labs working on this lncRNA
- a Radboud University Medical Center , Department of Cell Biology , Nijmegen , The Netherlands.
