FOXD2-AS1
Contents
Annotated Information
![](https://ngdc.cncb.ac.cn/lncrnawiki1/images/thumb/c/ce/LncRNA_FOXD2-AS_was_highly_expressed_in_NSCLC_tumors.jpg/400px-LncRNA_FOXD2-AS_was_highly_expressed_in_NSCLC_tumors.jpg)
LncRNA FOXD2-AS was highly expressed in NSCLC tumors [1].
![](https://ngdc.cncb.ac.cn/lncrnawiki1/images/thumb/4/41/FOXD2-AS1_regulates_Wnt-catenin_signaling_in_NSCLC_cells.jpg/400px-FOXD2-AS1_regulates_Wnt-catenin_signaling_in_NSCLC_cells.jpg)
FOXD2-AS1 regulates Wnt-catenin signaling in NSCLC cells [1].
Approved Symbol
FOXD2-AS1 (FOXD2 antisense RNA 1 (head to head))
Synonyms
MGC12982
Chromosome
1p33
RefSeq(supplied by NCBI)
NR_026878
Disease
Lung cancer
Function
Loss- and gain-function assays suggested that FOXD2-AS1 remarkably modulates the tumorigenesis of NSCLC through Wnt/β-catenin signaling.[1] FOXD2-AS1 overexpression promotes NSCLC progression.[1]
Expression
Compared with the adjacent tissues,lncRNA FOXD2-AS1 had significantly high expression in NSCLC tissues.[1].To be specific, high expression of lncRNA FOXD2-AS1 was shown in 23 cases of 45 (53.3%), in which unchanged was revealed in 10 cases (22%) and down-regulation in 12 cases (24%) [1]
Experiment | Forward primer | Reverse primer |
---|---|---|
qRT-PCR | 5'-TGGACCTAGCTGCAGCTCCA- 3' | 5'-AGTTGAAGGTGCACACACTG- 3'[1] |
Labs working on this lncRNA
- Department of Thoracic Surgery, The Second People's Hospital of Liaocheng, Liaocheng, Shandong 252600, China.
- Department of Thoracic Surgery, The Second People's Hospital of Liaocheng, Liaocheng, Shandong 252600, China. Electronic address: wchqba@163.com.