AA174084
AA174084 long noncoding RNA potentially may play a role during Gastric Cancer development
Contents
Annotated Information
Name
AA174084 (also known simply as AA) is a gastric juice long noncoding RNA [1]
Alias
NA
Functions
lncRNA-AA174084 is a tumor-suppressor gene which was suggested to play a tumor-suppressor role in Gastric Cancer (GC) tumorigenesis (including tumor initiation, progression, metastasis and prognosis) and proposed as a potential biomarker for screening EGC. [2]
Function Mechanism: tumor suppression
Biological Process: pathogenic process
Description: biomarker
Regulation
AA174084 is down‐regulated in GC tissues compared with the paired, adjacent, normal tissues. [2]
Disease
Disease: gastric cancer [2]
Dysfunction type: expression
Description: AA174084 may have potential as marker for the early diagnosis of GC
Labs Working
Department of Biochemistry and Molecular Biology, and Zhejiang Provincial Key Laboratory of Pathophysiology,Ningbo University, China
References
Virgilio E, Giarnieri E, Giovagnoli MR, Montagnini M, Proietti A, D’Urso R et al. Long non-coding RNAs in the gastric juice of gastric cancer patients[J]. Pathology - Research and Practice. 2018, 214(9):1239-1246.</ref>(1)
Shao Y, Ye M, Jiang X, Sun W, Ding X, Liu Z et al. Gastric juice long noncoding RNA used as a tumor marker for screening gastric cancer[J]. Cancer. 2014, 120(21):3320-3328.</ref>(2)
