ACTR3-AS1

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ACTR3-AS1, a set of biomarkers for the prognosis of patients with GBM,enabling a moreaccurate prediction of survival and revealingmorebiological functions.

Annotated Information

Approved symbol:ACTR3-AS1

Approved name: ACTR3 antisense RNA 1

HGNC ID:HGNC:53965

Alias symbols: AC104653.1

RefSeq ID:NR_110174

Characteristics

ACTR3-AS1 is a long noncoding RNA with esemble id ENSG00000115091, and is located on chromosome 2q14.1 [1].

Function

ACTR3-AS1 is enriched with ion binding, transport, cell-cell signaling, plasmamembrane parts, and more, and they were mainly related to neuroactive ligand-receptor interaction pathway, calcium signaling pathway, and the mitogen-activated protein kinase signaling pathway [1].

Regulation

NA

Diseases

  • Glioblastoma [1].

Expression

ACTR3-AS1 is expressed in brain tissues [1].

Labs working on this lncRNA

  • Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
  • Department of Neurosurgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People's Republic of China.

References

  1. 1.0 1.1 1.2 1.3 Lei BX, Yu L, Jung TA, Deng YF, Xiang W, Liu YW et al. Prospective Series of Nine Long Noncoding RNAs Associated with Survival of Patients with Glioblastoma[J]. J Neurol Surg Part A. 2018, 79(6):471-478.

Sequence

>gi|101060091|ref|NR_110174.1|Homo sapiens ACTR3 antisense RNA 1 (ACTR3-AS1), long non-coding RNA

000001 AGTAACACAT GACATCTTTC TCCCTCGAAT TAAAATGTGA CTTGGTTCAC CGGTTAAAAC GCAGAGGGAG ATGGAAATGA 000080
000081 CCAGGAGTCG AAAGGAGAAG ATAAGAGTGC AGTGGTGCAG TCATGGCTCA CTGCAGCGTC TGCCTCCTGG ACTCAAAGAA 000160
000161 TCCTCCTACC TCAGCCTCCC AAGTAGCTAG GACCACAGAG TTGTGCTCTC CTGCAGCGTT TTGCGGACGG CTGGCTATCT 000240
000241 TACCCAGAAT CAATCACACT GGGACACTGA AAAAAAAAAA AAAGGAAAAA AGAGCGAGGG AGTAATTCTA GCCTGTTTTT 000320
000321 ACAAGAACAC AGTGGCTATA GACAGTGCCA GTGTGAAGAT GACTCAGCAA ACGTGGAGAA CCAAAGATTC TAGGGCAGCA 000400
000401 CCAAAACTGG GAAAGCAATT ACAGCAGAAG TTGCCTTCCC CATGGTAGCT TAGCAACTTC GTGTCTCTCC AAGGCAGAGA 000480
000481 GGAAAATCAA GTCTAACAGG CCTTCCCGAA GGCTAGGTGT GAAATACCAG AAGCCATCTT TGTTTCTGGC GATGTCACTA 000560
000561 AATAAGTATT TGTTGATATA AAGTATTACA