LINC02590
LINC02590, long intergenic non-protein coding RNA 2590 involved in the carcinogenesis of gastric cancer.
Contents
Annotated Information
Name
Approved symbol:LINC02590
Approved name:long intergenic non-protein coding RNA 2590
HGNC ID:HGNC:53861
Alias symbol:AC016735.2
Characteristics
LINC02590 is a long non-protein coding RNA gene located at chromosome position 2p21. [1]
Function
AC016735.2 may regulate ALOX15 and have a role in the progression of GC.[1]
Regulation
According to the findings of the transcriptome sequencing and bioinformatics analyses, AC016735.2 was upregulated and RT-qPCR validation confirmed that AC016735.2 was upregulatedin GC tissues compared with normal adjacent tissues.[1]
Expression
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| RT-qPCR | 5'-CTGCTTCTCACTGCCTCG- 3' | 5'-TTTCCCAAATGGTCCTCC- 3'[1] |
It is a differentially expressed lncRNA in gastric cancer tissue.[1]
Disease
Gastric cancer [1]
Labs working on this lncRNA
Department of Laboratory Medicine, Shanghai Shuguang Hospital Affiliated with Shanghai University of TCM, Shanghai 200021, P.R. China
References
Sequence
>ENST00000438158.1, Homo sapiens lincRNA LINC02590cdna
000081 CCTGCCAGGC CATGGCAGAA TTGCTGTTCC CAGGAAGGCA GGCCTGGCCT GGGCTGAAAA GCAGATCTGG GTTCTAATCT 000160
000161 CCCTTCTGCA TGGACCTGCG GGTGACACAA GCTTGGTGCC TTCTCCTCTC TGAACTTCAA GTCCTTACTT GGACAAGATG 000240
000241 GCCTGGCTCC TCCCAGCCCT GGATTTGGGG ATGCTCCGAT GCTGCCTGGG AGCCCAGTCT GATCATGGTG GCCTGGAAAT 000320
000321 CAAGGCTAAG CGAAAGGAAA GCCTGAAAGA GCTGCACTCT AAGCACCACA GCAGGACTTG CCCCTGAATG GAGATGGGGC 000400
000401 TGGGGCAGGA AGGTGGCAGG GAGGGGCTGG GCCCTGTGAC TGTCACCTCC AGGTTGGAGG AGTGGGGAGG GAAAGGCAGG 000480
000481 GCAGGGTGCG TTATCACACA CACACTCACC CACATACACT CAAGCACACA CCACAGAGTC CAAGGAAAAC CTGTTTCTGT 000560
000561 CCTAGCACT
