MIR122HG
Contents
Annotated Information
Name
Approved symbol:MIR122HG
Approved name:MIR122 host gene
HGNC ID:HGNC:53821
Alias symbol:lnc-pri-miR-122
RefSeq ID:NR_170244
Characteristic
MIR122HG transcripts are capped but not polyadenylated[1] MIR122HG 3' end is generated by Drosha cleavage and not by CPA[1] Pol II transcribing lnc-pri-miR-122 fails to recognize PAS (polyadenylation site) even when Microprocessor cleavage is inhibited.[1]
Expression
MIR122HG transcripts are capped but not polyadenylated[1]
Labs working on this lncRNA
- Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
References
- ↑ 1.0 1.1 1.2 1.3 Dhir A, Dhir S, Proudfoot NJ, Jopling CL. Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs. Nat Struct Mol Biol. 2015 Apr;22(4):319-27. doi: 10.1038/nsmb.2982. Epub 2015 Mar 2. PubMed PMID: 25730776; PubMed Central PMCID: PMC4492989.
