NONHSAT122918
Revision as of 12:11, 6 October 2014 by 111.204.253.116 (talk)
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Contents
Annotated Information
Transcriptomic Nomeclature
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Function
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Regulation
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Expression
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Allelic Information and Variation
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Evolution
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Labs working on this lncRNA
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References
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Basic Information
Transcript ID |
NONHSAT122918 |
Source |
NONCODE4.0 |
Same with |
, |
Classification |
intergenic |
Length |
416 nt |
Genomic location |
chr7+:116594674..116608628 |
Exon number |
3 |
Exons |
116594674..116594733,116595028..116595207,116608453..116608628 |
Genome context |
|
Sequence |
000001 CGAAACACAA AGTAAATTTC GAGCTAAGGG TTACAGTCCT TTAAATCTGG AAATTTCAAG TATCCCTCGG GATCGTGTCC 000080
000081 CTGGGAGGCG GATAGGATTC AGCACTCTAG AATTGTCTCA CCATTTGAAT AGGTGCTGCT CAGCCCTTTT GAGTCTGTCA 000160 000161 TCGGAAAGAC CATGGCTTTC TCGCTTTTCA TCTTTTTGGA TGGCTGCTTG TCGCAATATT GTCTTCTTCG CTTTAGACAA 000240 000241 tgtcttacta tgttgaccgt gctggactcg aattcctggg ctcaagcaat ccttctgcct caaccttctg attatttcga 000320 000321 ctacgggtgt gcgccaccat gcctggcTTA GAAAAGGACT TTATGTTGAA CCTCTTTTCT CTTACAATCA AATAATAAAT 000400 000401 TCATTGAGTC ATACTA |
Annotation (From lncRNAdb)
Section | Description |
---|---|
ID | ST7OT |
Characteristics | Four noncoding RNAs from the RAY1/ST7 gene locus. Complex gene locus with a large number of coding and noncoding isoforms. ST7OT1 & 2 are antisense to ST7. ST7OT3 & 4 are on the sense strand. ST7OT1 - ~2kb unspliced antisense transcript that initiates in intron 1 of ST7, covers the first exon and terminates in the ST7 promoter region. Polyadenylated. Nb: it also overlaps exon 1 of ST7OT4. ST7OT2 - Spliced antisense transcripts. Multiple isoforms that share either some 5' or some 3' exons. Isoforms are between 900-1300 bp, with 4-6 exons and polyadenlyated. ST7OT3 - Spliced ~1kb transcript. Begins in intron 10 of ST7, shares exons 11-13 and sometimes 14 & 15 with ST7 plus has a number of unique exons. Some exons may also act as a alternative 3' end for ST7. ST7OT4 - Multiple spliced transcripts within the long first intron of ST7. However, Refseq ST7OT4 transcript may be protein coding. Transcription begins just ~200bp downstream from the end of first ST7 exon. |
Expression | ST7OT1 - abundantly expressed in testis, also expressed in cerebellum, skeletal muscle, uterus, cerebellum, spinal cord, fetal brain, and prostate. ST7OT2 - testis, fetal brain, cerebellum, mammary gland, fibroblasts. ST7OT3 - expression only detected in cerebellum. ST7OT4 - no expression detected. |
Conservation | ST7OT1 - some conserved sequence with mouse, most of this is where ST7OT1 overlaps the first exon of ST7 however. ST7OT2 - 3' end of some isoforms shows some conservation with mouse. ST7OT3 - some conserved sequence, most of this is shared exons with ST7 though. ST7OT4 - sequence not conserved with mouse. |
Misc | ST7OT1 - NCBI Gene ID: 93653. ST7OT2 - NCBI Gene ID: 93654. ST7OT3 - NCBI Gene ID: 93655. ST7OT4 - NCBI Gene ID: 338069 |
Predicted Small Protein
Name | NONHSAT122918_smProtein_239:310 |
Length | 24 |
Molecular weight | 2499.7052 |
Aromaticity | 0.173913043478 |
Instability index | 45.0826086957 |
Isoelectric point | 4.36907958984 |
Runs | 6 |
Runs residual | 0.0331262939959 |
Runs probability | 0.0293823235 |
Amino acid sequence | MSYYVDRAGLEFLGSSNPSASTF |
Secondary structure | LEEEEELHHHEEELLLLLLLLLL |
PRMN | - |
PiMo | - |