NONHSAT113225

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Annotated Information

Name

KRASP1: KRAS Pseudogene 1

Characteristics

Processed pseudogene of KRAS oncogene on 6p12-p11 (McGrath (1983)).

Function

Probable competing endogenous RNA (ceRNA). KRASP1 is hypothesised to act as a decoy for miRNAs targeting KRAS, similar to how PTENP1 acts a decoy for PTEN (Poliseno (2010)). Expression of the KRASP1 3'UTR sequence lead to de-repression of KRAS mRNA levels and increased cellular proliferation (Poliseno (2010)).

Expression

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Conservation

Pseudogene sequence at this locus only present in some primates.

Misc

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Transcriptomic Nomeclature

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Regulation

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Allelic Information and Variation

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Evolution

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Labs working on this lncRNA

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References

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Basic Information

Transcript ID	NONHSAT113225
Source	NONCODE4.0
Same with	,
Classification	intergenic
Length	865 nt
Genomic location	chr6+:54635169..54636037
Exon number	2
Exons	54635169..54635601,54635608..54636037
Genome context
Sequence	000001 CTGCATCATA AATTCCTAAG GAATGGAATG AGCTTTGACT GCCTTACCTT GAGAATAAGC ATATTCACGT AAAGTATATA 000080 000081 AGACAAATAC TGGTTTAGAT GAAGCTCGGC CAGTACTCCC GGCCTCCGCC ATTTCGGACT GGGAGCTCCG TGGCGCAGGC 000160 000161 ACTGAAGGCG GCGGCAGGGC CAGAGGCTCA GCGGCTCCCA GACCTGCTGA AAATGACTGA ATATAAACTT GGCGGTAGTT 000240 000241 GGAGCTGGTA GCGTAAGCAA AAGTGTCTTG ACGATACAGC TAATTCAGAA TCATTTTGTG GACCAATATG ATCCAACAAT 000320 000321 AGAGAATTCC TACAGGAAGC AAGTAGTAAT TGATGGAGAA ACCTGTCTCT TGGATATTCT TGACACAACA GGTCAAGAAG 000400 000401 AGTACAATGC AATGAGGACC AGTACATGAG GACTGGGGGG GGGGGGGGCT TTCTTTGTGT ATTTGCCATA AATAATATTA 000480 000481 AATCATTTGA AGATATGCAC AATTATAGAA AACAAATTAA AAGATTTAAG GACTCTGAAG ATGTGCCTAT GGTCCTAGTA 000560 000561 GGAAATAAAT GTGATTTGCC TTCTAGAACA GTAGACACAA AAGGCTCAGG ACTTAGCAAG GAGTTAGGGA ATTCCCTTTA 000640 000641 TTGAAACCAG CAAAGACAGG GTGTTAATGA TGCCTTCTAT ACATTAGTTT GAGAAATAAA AGATGAGCAA AGATGGTAAG 000720 000721 AAGAAGAAAA GTCAATGACA AAGTGTGTAA TTATGTAAAT ACAATTAGTA CTTTTTTCTT AAGGCATAGC TTAAGTAAAA 000800 000801 CTGGTAATTT TTATACATTA CACTAAACTA TTAGCATTGT TTTAGCATTA CCTAATTTTT TTCCT

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