NONHSAT104559
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Contents
Annotated Information
Name
Alpha 250/ Alpha 280
Characteristics
Two overlapping antisense RNAs from intron 1 of the human ribosomal protein 14 (Rps14) gene, identified by RNase Protection Assay (RPA).. RPA expression analysis using both cell extracts and cell-free transcription system indicates full-length sizes of 250 and 280 nt, respectively. Transcripts terminate at the same nucleotide, therefore alpha-250 overlaps alpha-280 along its whole length.. Transcription of both RNAs is resistant to high concentrations of RNAPII inhibitor alpha-amanitin.
Function
Regulates RPS14 transcription.. Each lncRNA can interact with the Rps14 gene loci to stimulate its expression in-trans.. Each lncRNA is transcribed through a known enhancer with putative transcription factor binding abilities, suggesting the 'enhancer' may be the transcribed RNA, which could be recruiting transcription factors to the Rps14 gene.
Expression
Ubiquitously expressed in the human tissues and cell lines examined. . Alpha-250 was almost exclusively cytoplasmic. Alpha- 280 was mostly in the nucleus.
Conservation
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Misc
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Transcriptomic Nomeclature
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Regulation
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Allelic Information and Variation
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Evolution
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Labs working on this lncRNA
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References
Annotation originally sourced from lncRNAdb.
Basic Information
Transcript ID |
NONHSAT104559 |
Source |
NONCODE4.0 |
Same with |
, |
Classification |
antisense |
Length |
290 nt |
Genomic location |
chr5+:149828969..149829258 |
Exon number |
1 |
Exons |
149828969..149829258 |
Genome context |
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Sequence |
000001 TACGCTGTGC AGCTCAAACG CGGCCGTGGC CGTGGCCGTA TTGCGGGGCC GAGGCCTTAA AAGGCTGGAC CCGCACTCAC 000080
000081 CCTTACTTCA CAAGCTCCTC CCTGAAAGCA AAACGGGCCT TCTGAGACCA GGAACGAACT CAATCCCGAG TTGGCCAGGA 000160 000161 TCCAGGTGGG CCAGCCGCGC GTCTCTTGCC CGGCACCTAG CTCGGTTCCC ACGGAAAGAC CCCCGTCTCT CGTCCCAAGC 000240 000241 CCCACAGGGT CCCCTCGCCG CAGGATGCCC CCCGATTGTC GCGCCCGGGC |