ENST00000430058.1
PTCSC2,shorted for papillary thyroid carcinoma susceptibility candidate 2, may functions in papillary thyroid cancer.
Contents
Annotated Information
Name
PTCSC2:papillary thyroid carcinoma susceptibility candidate 2 (non-protein coding)(HGNC nomenclature)
disease
thyroid carcinoma
Characteristics
PTCSC2, a 1635 bp long intergenic noncoding RNA gene and locus in 9q22.33,named papillary thyroid cancer susceptibility candidate 2 (PTCSC2)[1].
Function
PTCSC2 plays an important role in the predisposition to PTC(papillary thyroid cancer)[1].
Regulation
PTCSC2 is involved in the regulation and interaction of coding and noncoding genes[1]. The cells transfected with the PTCSC2-c construct showed a strong RT-PCR band in the presence of reverse transcriptase, but not in the absence of reverse transcriptase.[1].
Expression
Forced expression of PTCSC2 in the BCPAP cell line affected the expression of a subset of noncoding and coding transcripts with enrichment of genes functionally involved in cell cycle and cancer.
Labs working on this lncRNA
- Human Cancer Genetics Program and Department of Molecular Virology, Immunology, and Medical Genetics[1].
References
Basic Information
| Transcript ID |
ENST00000430058.1 |
| Source |
Gencode19 |
| Same with |
lnc-C9orf156-3:1,NONHSAT133533,PTCSC2 |
| Classification |
intergenic |
| Length |
204 nt |
| Genomic location |
chr9-:100568217..100572290 |
| Exon number |
2 |
| Exons |
100568217..100568306,100572177..100572290 |
| Genome context |
|
| Sequence |
000001 TGTCCTGGGG GAATAATTAT GTTCCCTGTC TTGGGAGCCT TTCTTCAGGG AGCTTGATGG TTCCAACCCA CCCAGGAGCC 000080
000081 TGGGACATCT GTGCCCCTGG GCAATCCCCT GCAGTTTCCT GATTCCAAGA TGAGGGGGTA GAATCCGAAG ATCTCCAAGG 000160 000161 CCTTGATGAG TGCTACCAGT CTGCAAATTC CCAAGCCAAG TTCT |
