PRNT
Revision as of 14:23, 28 July 2017 by Jiabao Cao (talk | contribs)
Contents
Annotated Information
Name
PRNT:prion locus lncRNA, testis expressed
M8
Characteristics
PRNT is located in 3 kb downstream of PRND(a gene), and is human homolog of mouse Doppel.[1] The PRNT gene is the nearest gene to PRNP and PRND in humans, and like PRNP and PRND, it has a two-exon structure, but has no detectable sequence homology to them. It is 48% comprised of transposon homologies (LINE-2 and MER elements) [2]
Sequence
>NR_024267.1 Homo sapiens prion locus lncRNA, testis expressed (PRNT), transcript variant 1, long non-coding RNA
000001 GTCCCTAGAG ACAGCCTGGA AAGATTGGGT GCCAGCTGCA GAGAGGAGAG CAAGGCGACC AAACGCAGGG TAAGGTCTGG 000080
000081 AGGTGCTCAT AGTTCACTAC GGGACATGTA CATGGAAGTG AATAATTATG TCACAAGGTG CCAAGGGGGC TAGTTACCTC 000160
000161 ACATAGGATC TTAGAAAAGG TCTCCTGGAG ACCATGTCTG AGCTGGTCCT GAGGTGTGAG TAGGGATTCT CCGCAGGGCG 000240
000241 GGGAAGGACT TGAAAGAGTC TGGCAATATG GAGCACATCA GGATTATGGA AGGTGAGCTT GGAGAACAAG GCAGAGTCTA 000320
000321 GCCTGTGAAA GGCCTCTTGC AATTTGTTGA GGATCCATGA CCTTCTCCCA TGCATGGTGA AATGCCCTTA AAGGATTTTG 000400
000401 AATAGATTTA AAAGACACTC AAAAACAAAA AACGGTAGAT TCAAAATAGA CGGTAGGGAT CGCTTTCTTC CGTTTTCTTT 000480
000481 GAAGGATCAG AAGTGTTTAC CACCACCTGG ATTGTTTTTG GGCTTTCAGC TGTGGCTGCC TGCAGCCCAT CCTGCCCCCA 000560
000561 GCACCTAGAG TCATCTTTAG AAATGCAAGC CTGATCGTGG AATCCACCTT CCTAACACCC TTCAGTGCCC TCCTCTTCGT 000640
000641 TACACCCTTA CTATACAAAC GATAGTCCAT GGACCAGCAG CATCAACATA ACCAGGGAGC TTGTTAGAAA TGTAGAATCT 000720
000721 GGTCCATCCC AAACCTGACG AAGCAGAAGC TGCATTTTGC CAAGATCCCA GGGAATTTGT GTGCCCGTTA TGGTTTGCGA 000800
000801 AGTGCTTCCC AAGAGAACAT ACGGCAAGCC AGAGGGATCT TTGCAGATCT TGCTCCTTTC ATTCTCTGGC CTCATCTTGT 000880
000881 CGCTCTCCTC CATCCGTGCC CACATCCCCA CTGTACTGGA CCGCTTGCAG CTCCTTGAAT GCAGCATAGT CTTGTTTTCT 000960
000961 TTTTTGCAGT GATTCTACAT CTTTCCCATC TTCTCCACCT GGATGCCTCC ATCCATCCTT TCAGACTTCC CTTCTCTAGC 001040
001041 AAACCTTTCT TGCTAATTCC CATGTCTAAC ACAACACTTC CCCATACTGC ATGGCCATTA TCCTTTCTGC ATCAGACTGT 001120
001121 GAGCACCTTG AAGGCAGTGG CAGTGACTCA TTCATTGTGG CATCTGCAGA TTCCAGTGGA CTGCCAGGCA TGCAATAGAA 001200
001201 AATCAAAAAA GATTTACTGC TAAATAATCC TCAACTCCAG TGGCAGCTCC ATGTGCCATT TCTCTTCCGC TCTGGCCTCG 001280
001281 GCTCTTCCTG TGCCTACCTG GGGCTTGGCT TTCACCTAGG TGTCTGCATG GAAGGGAGAG CGACCTGGAG GACCATCGCC 001360
001361 AATCCATCAA TAGCCTCCCG GTTGAGATGA CTTCAGCTCT GATTTGGAAG AGCTATGATA TTGTTTATAG GAGTGAATTA 001440
001441 ATATGTGTAA AGGTTACAAA GTAAACAGTT AAATTAAATT AATTGTGCTG GAGCAGGTCA AACAGGCTTC TGAGAGATGA 001520
001521 ACATACACAT CTCTATTAAC TCCACATTCA GTGAGTGTGG GTAACTTGAA ATTGGCTGGG TCACCATTTA CATCATAGAA 001600
001601 ATTGGCAAAT AGTACAAATT AGGGCTCCCT CACCCCTACT CGGGCATAGA GCTGGTACAC TAGCACACCT CTGGTTATAC 001680
001681 ATGCATGCGT GTGCCACCAG AACAAAACAC CTAACAGCAG GCACGTTGCC TCTGTTGCCC ACCATTACAG CTCCCGCACG 001760
001761 GAGCAGACAG ACTCATGGCA GGAATTGAAT GCATGTTTGT CGAGTGGAAG CATGAACAAA TCCACAAAAT GCCCAAGATG 001840
001841 AGGCAAAGAA GGACATTGGC TCAAATGTTA AACATAAGTT AGGAGCTGAG ATAATGCCCA GAGGAAAAAT GTTCTGTAAT 001920
001921 TCTAAGTAAA ACCCATCTCT AAGGCAGGAT GCTGCTTATG AGGGCTCCAC AGACAGATGG GGGAGGCCTG GGTCCTGCCC 002000
002001 TTGGAAAGAG TCTGACAGCT CGACTTCTGG AAACAGCCAT CTGCACAGGT CAACATCTTC TTAGCTGACA GGGAGCAGAT 002080
002081 TTGCAGACCA CATCACATTT GAAATTCCAG AAGAAACTTC TTGGAGTCTG CTCTTGTGCA AATGAGCCTA GAAAGCCCGT 002160
002161 TAACTTTGGG TGGAGGCTTC CACTGTTTGG CTATCCCAAG TGGGCCCAAA GCTAAGGAAA ACCCACCAGC CCTTTGCTTC 002240
002241 CTGCTTCCTC TATTTGTTTG CCCCAGGAAA TCAGAGGTGA TGACATGATT TGGCTTGGGC ACGACAGGAA TAAACGATAT 002320
002321 TTAAGAGACG TCAAAAAAAA AAAAAAAAAA AAA
000081 AGGTGCTCAT AGTTCACTAC GGGACATGTA CATGGAAGTG AATAATTATG TCACAAGGTG CCAAGGGGGC TAGTTACCTC 000160
000161 ACATAGGATC TTAGAAAAGG TCTCCTGGAG ACCATGTCTG AGCTGGTCCT GAGGTGTGAG TAGGGATTCT CCGCAGGGCG 000240
000241 GGGAAGGACT TGAAAGAGTC TGGCAATATG GAGCACATCA GGATTATGGA AGGTGAGCTT GGAGAACAAG GCAGAGTCTA 000320
000321 GCCTGTGAAA GGCCTCTTGC AATTTGTTGA GGATCCATGA CCTTCTCCCA TGCATGGTGA AATGCCCTTA AAGGATTTTG 000400
000401 AATAGATTTA AAAGACACTC AAAAACAAAA AACGGTAGAT TCAAAATAGA CGGTAGGGAT CGCTTTCTTC CGTTTTCTTT 000480
000481 GAAGGATCAG AAGTGTTTAC CACCACCTGG ATTGTTTTTG GGCTTTCAGC TGTGGCTGCC TGCAGCCCAT CCTGCCCCCA 000560
000561 GCACCTAGAG TCATCTTTAG AAATGCAAGC CTGATCGTGG AATCCACCTT CCTAACACCC TTCAGTGCCC TCCTCTTCGT 000640
000641 TACACCCTTA CTATACAAAC GATAGTCCAT GGACCAGCAG CATCAACATA ACCAGGGAGC TTGTTAGAAA TGTAGAATCT 000720
000721 GGTCCATCCC AAACCTGACG AAGCAGAAGC TGCATTTTGC CAAGATCCCA GGGAATTTGT GTGCCCGTTA TGGTTTGCGA 000800
000801 AGTGCTTCCC AAGAGAACAT ACGGCAAGCC AGAGGGATCT TTGCAGATCT TGCTCCTTTC ATTCTCTGGC CTCATCTTGT 000880
000881 CGCTCTCCTC CATCCGTGCC CACATCCCCA CTGTACTGGA CCGCTTGCAG CTCCTTGAAT GCAGCATAGT CTTGTTTTCT 000960
000961 TTTTTGCAGT GATTCTACAT CTTTCCCATC TTCTCCACCT GGATGCCTCC ATCCATCCTT TCAGACTTCC CTTCTCTAGC 001040
001041 AAACCTTTCT TGCTAATTCC CATGTCTAAC ACAACACTTC CCCATACTGC ATGGCCATTA TCCTTTCTGC ATCAGACTGT 001120
001121 GAGCACCTTG AAGGCAGTGG CAGTGACTCA TTCATTGTGG CATCTGCAGA TTCCAGTGGA CTGCCAGGCA TGCAATAGAA 001200
001201 AATCAAAAAA GATTTACTGC TAAATAATCC TCAACTCCAG TGGCAGCTCC ATGTGCCATT TCTCTTCCGC TCTGGCCTCG 001280
001281 GCTCTTCCTG TGCCTACCTG GGGCTTGGCT TTCACCTAGG TGTCTGCATG GAAGGGAGAG CGACCTGGAG GACCATCGCC 001360
001361 AATCCATCAA TAGCCTCCCG GTTGAGATGA CTTCAGCTCT GATTTGGAAG AGCTATGATA TTGTTTATAG GAGTGAATTA 001440
001441 ATATGTGTAA AGGTTACAAA GTAAACAGTT AAATTAAATT AATTGTGCTG GAGCAGGTCA AACAGGCTTC TGAGAGATGA 001520
001521 ACATACACAT CTCTATTAAC TCCACATTCA GTGAGTGTGG GTAACTTGAA ATTGGCTGGG TCACCATTTA CATCATAGAA 001600
001601 ATTGGCAAAT AGTACAAATT AGGGCTCCCT CACCCCTACT CGGGCATAGA GCTGGTACAC TAGCACACCT CTGGTTATAC 001680
001681 ATGCATGCGT GTGCCACCAG AACAAAACAC CTAACAGCAG GCACGTTGCC TCTGTTGCCC ACCATTACAG CTCCCGCACG 001760
001761 GAGCAGACAG ACTCATGGCA GGAATTGAAT GCATGTTTGT CGAGTGGAAG CATGAACAAA TCCACAAAAT GCCCAAGATG 001840
001841 AGGCAAAGAA GGACATTGGC TCAAATGTTA AACATAAGTT AGGAGCTGAG ATAATGCCCA GAGGAAAAAT GTTCTGTAAT 001920
001921 TCTAAGTAAA ACCCATCTCT AAGGCAGGAT GCTGCTTATG AGGGCTCCAC AGACAGATGG GGGAGGCCTG GGTCCTGCCC 002000
002001 TTGGAAAGAG TCTGACAGCT CGACTTCTGG AAACAGCCAT CTGCACAGGT CAACATCTTC TTAGCTGACA GGGAGCAGAT 002080
002081 TTGCAGACCA CATCACATTT GAAATTCCAG AAGAAACTTC TTGGAGTCTG CTCTTGTGCA AATGAGCCTA GAAAGCCCGT 002160
002161 TAACTTTGGG TGGAGGCTTC CACTGTTTGG CTATCCCAAG TGGGCCCAAA GCTAAGGAAA ACCCACCAGC CCTTTGCTTC 002240
002241 CTGCTTCCTC TATTTGTTTG CCCCAGGAAA TCAGAGGTGA TGACATGATT TGGCTTGGGC ACGACAGGAA TAAACGATAT 002320
002321 TTAAGAGACG TCAAAAAAAA AAAAAAAAAA AAA
Labs working on this lncRNA
- MRC Prion Unit, Department of Neurodegenerative Diseases, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK.[1]
- Department of Biology, McGill University, Montreal, QC, Canada. paul.harrison@mcgill.ca[2]
References
- ↑ 1.0 1.1 Makrinou E, Collinge J, Antoniou M. Genomic characterization of the human prion protein (PrP) gene locus. Mamm Genome. 2002 Dec;13(12):696-703.
- ↑ 2.0 2.1 Harrison PM, Khachane A, Kumar M. Genomic assessment of the evolution of the prion protein gene family in vertebrates. Genomics. 2010 May;95(5):268-77.
