DDX11-AS1

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Annotated Information

Approved Symbol

DDX11-AS1 (DDX11 antisense RNA 1)

Synonyms

CONCR

CONCR Is a Nuclear lncRNA Negatively Regulated by p53 and Activated by MYC[1]
CONCR Is Upregulated in Multiple Cancer Types[1]

Chromosome

12p11.21

RefSeq(supplied by NCBI)

NR_038927

pubmed IDs

27477908

Characteristics

DDX11-AS1 is a divergent non-overlapping transcript of the protein-coding gene DDX11, which is a predominant nuclear lncRNA. ChIP-seq data from ENCODE shows that MYC is bound to DDX11-AS1 promoter region in multiple cell types.

Expression

DDX11-AS1 is expressed in a panel of different human cell lines and upregulated in multiple cancer types. [1]

Regulated

DDX11-AS1 is negatively regulated by p53 and activated by MYC. [1]

Function

DDX11-AS1 contributes to tumor growth. [1]
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