HOXC-AS1
Contents
Annotated Information
Approved Symbol
HOXC-AS1 (HOXC cluster antisense RNA 1)
Chromosome
12q13.13
RefSeq(supplied by NCBI)
NR_047504
Expression of lncRNA HOXC-AS1 and HOXC6 in normal tissues and atherosclerotic plaques.[1]
Characteristics
lncRNA HOXC-AS1 is located on chromosome 12 and its transcription position is nearby.[1]
Expression
Compared to normal renal arterial intima, HOXC-AS1 is downregulated in carotid atherosclerosis.[1] Ox-LDL can suppress the expression of lncRNA HOXC-AS1 and HOXC6 in THP-1 macrophages.[1]
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| qRT-PCR | 5′-CTGCGACACTTCCCCACC-3′ | 5′-CTACTT GCCCACGACCGA-3′[1] |
Function
Overexpression of HOXC-AS1 promotes expression of HOXC6 at mRNA and protein levels.
Labs working on this lncRNA
- Laboratory Medicine Center, Nanfang Hospital, Southern Medical University , Guangzhou, China .
- Department of Anesthesiology, Nanfang Hospital, Southern Medical University , Guangzhou, China .
- Department of Vascular Surgery, Nanfang Hospital, Southern Medical University , Guangzhou, China .
- Department of Cardiology, Nanfang Hospital, Southern Medical University , Guangzhou, China .
