MDS2
Contents
Annotated Information
Approved Symbol
MDS2 (myelodysplastic syndrome 2 translocation associated)
Chromosome
1p36
OMIM ID
607305
RefSeq(supplied by NCBI)
NR_027042
pubmed IDs
12203785
Analysis of the expression levels of genes surrounding MDS2 in the patient and in three unrelated normal bone marrow samples[1]
Characteristics
The MDS2 gene is approximately 13 kb and is flanked by E2F2 and ID3 at its 5� end (telomeric) and by RPL11 and TCEB3 at its 3�' end (centromeric) and gives rise to four alternatively spliced products.[1] The predicted ETV6-MDS2 fusion product contains 58 amino acids, starting at the first ATG of ETV6 and ending in aTGA stop codon only four amino acids after ETV6 exon 2.[1]
Expression
Oligonucleotide primers' sequences of MDS2 are showed as follow.
| Primer | Sequences |
|---|---|
| NG-R1 | GCGACAGCCAGGTCTTAA [1] |
| NGex1-F1 | CCGCCTGTATCCGTGCCTGTT [1] |
| NGex6-F1 | AGCAGTCCAGCTATGAGGGGAGGT [1] |
| NGex6-R1 | TGGAGGCGACAGCCAGGTCTTAA [1] |
| NGex6-F2 | GACCCTGGAGAGGCCATTAAGACCT [1] |
| NGex6-R2 | GTCTTAATGGCCTCTCCAGGGTCAG [1] |
Disease
MyelodysplasticSyndrome [1]
Labs working on this lncRNA
- Department of Genetics, University of Navarra, Pamplona, Spain.
