CLLU1
Sequence changes in the origin of CLLU1 from noncoding DNA [1].
Genomic organization and structure of CLLU1 transcripts [2].
Similarity between the CLLU1-encoded protein and IL-4. [2].
Contents
Annotated Information
Approved Symbol
CLLU1 （chronic lymphocytic leukemia up-regulated 1
Chromosome
12q22
RefSeq ID
NM_001025233
OMIM ID
616988
RefSeq(supplied by NCBI)
NR_027932
pubmed IDs
"19726446, 22102831"
Characteristics
CLLU1 is located on chromosome 12q22, surrounded by genes that are active in germinal center B cells and CLL cells [2]. The CLLU1 region does not include any known miRNAs.[2]
Expression
It is originally recognized as a highly expressed gene in chronic lymphocytic leukemia (CLL).[2]
Labs working on this lncRNA
- Smurfit Institute of Genetics, University of Dublin, Trinity College, Ireland.[1]
- Department of Hematology, 4041, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, DK. am.buhl@get2net.dk [2]
References
- ↑ 1.0 1.1 Knowles, D.G. and A. McLysaght, Recent de novo origin of human protein-coding genes. Genome Res, 2009. 19(10): p. 1752-9.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Buhl, A.M., et al., Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia. Blood, 2006. 107(7): p. 2904-11.
