G2E3-AS1

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Annotated Information

Approved Symbol

G2E3-AS1 (G2E3 antisense RNA 1)

Synonyms

CAT1647

Chromosome

14q12

RefSeq(supplied by NCBI)

XR_001750710

The expression levels of CAT266, CAT1297 and G2E3-AS1(CAT1647) in other urological tissue types[1]

Disease

Bladder cancer

Characteristics

G2E3-AS1 is significantly enriched in the cytoplasmic fraction. [1]

Function

Knockdown G2E3-AS1 activate apoptotic pathways leading to decrease in migration capacity of bladder cancer cells.[1]

Expression

G2E3-AS1 is up-regulated in bladder cancer. [1] Expression levels of G2E3-AS1 is found to be significantly higher in high grade bladder cancer (p = 0.027).[1]

Labs working on this lncRNA

  • Department of Urology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands [1]

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Dudek AM, Boer SJ, Boon N, Witjes JA, Kiemeney LALM, Verhaegh GW. Identification of long non-coding RNAs that stimulate cell survival in bladder cancer. Oncotarget. 2017 May 23;8(21):34442-34452. doi:10.18632/oncotarget.16284.
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