C5-OT1

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Annotation

Name

C5-OT1

Alias

C5T1

Disease

Disease: rheumatoid arthritis (PMID:26673966)

Dysfunction type: locus

Description: LncRNAs can regulate the transcript levels of genes in the same genomic region.However, lncRNAs linked to the transcription of candidate risk genes in loci associated to rheumatoid arthritis (RA) have not yet been identified.Our data show the identification of a novel lncRNA C5T1lncRNA that is fully located in the associated region and influences transcript levels of C5, a gene previously linked to RA pathogenesis.


Function

Function Mechanism: transcriptional regulation (PMID:26673966)

Biological Process: pathogenic process

Description: NA