UVRAG-DT

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UVRAG-DT, UVRAG divergent transcript, is a novel diagnostic biomarker for postmenopausal osteoporosis (PMOP).

Annotated Information

Name

UVRAG-DT: UVRAG divergent transcript (HGNC nomenclature) LOC100506113 [1].

Characteristics

UVRAG-DT is a two exon transcript of 689 bp that is found on human chromosome 11q13.5 [1].

Function

Downregulation of UVRAG-DT may be a prognostic factor for postmenopausal osteoporosis patients [1].

UVRAG-DT and LOC105374771 may be involved in pathogenesis of postmenopausal osteoporosis (PMOP) by regulating the expression of diacylglycerol O-acyltransferase 2 and LGALSL, respectively [1].

Regulation

NA

Diseases

  • Postmenopausal osteoporosis (PMOP) [1]

Expression

UVRAG-DT is downregulated in postmenopausal osteoporosis (PMOP) [1]

Labs working on this lncRNA

  • Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China. [1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Fei Q, Bai X, Lin J, Meng H, Yang Y & Guo A. Identification of aberrantly expressed long non-coding RNAs in postmenopausal osteoporosis[J]. International journal of molecular medicine. 2018, 41(6):3537-3550.

Sequence

>gi|392973718|ref|NR_144531.1| Homo sapiens UVRAG divergent transcript (UVRAG-DT), long non-coding RNA

000001 CACTTCCGCC CTCACTGGTT GCCGTGGTAA CAGGCCTCCG GTGGAGGGCG GGGACCCTCG GAAGCCAGCT GGGTGGCGAT 000080
000081 CGCTTGTCTG CCTTGGCAGG CCCCTTGTGC AGTCTTTTCC CGGCGTGAGC GTGCAGGGAT TGAAAAGGAA TGCTTTATGG 000160
000161 TTCAGCAGAG AGCCACCACG CAGGATGCAC TGGGACCTGA GAACCGTCGG GCAGTCCCAC GAGCTCTTTC ATGACCAGCT 000240
000241 CCAACCGACA AGTACACGCC CCTTCGCACT CCACTAGCTA GTAAGCTGAG CTACAAGGTG TGCCAGGCAC CCAGGACGCC 000320
000321 GATTCACCGC TTCAGTGAAG GCCCAGCTCA AATGCCACCT CTTCCATGAA GACTTCCGTG ATCCACAATG ATAGCATCTC 000400
000401 CAGCAATTGC TTCTATAATG AATAGCATGA GTCATTCTGC AGGATGTTGA TCTTCCTTTT TTTACTCCTA GACTGAATTT 000480
000481 TTCCACCACC TGGATGAACA TAGCAGAAAG AACATAGTGT TTTAGAGTCA GACACAATAG GAATCAGGCA CTTTGGAATC 000560
000561 TTGGCTCTAC CACCTTTGAG CTATGTATCC CAAGGCAAGT CACTTCCCCT CTCTCAGCTT TAAAATAGTA ATAGGATTGC 000640
000641 TGTAGGGATT AAAGTAAATC AACATATGTA AAGTGCCCAC ACAAAAAAA