UGDH-AS1

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UGDH-AS1, a long non-coding RNA linked to intervertebral disc degeneration.

Annotated Information

Approved Symbol

UGDH-AS1

Approved Name

UGDH-AS1: UGDH antisense RNA 1

Characteristics

UGDH-AS1 belongs to a class of long non-coding RNA located at chromosome 4p14 [1]. UGDH-AS1 act as ceRNA [1].

Function

UGDH-AS1 regulates hsa-miR-140 by forming hsa-miR-140 regulatory network with two other RNAs [1]. UGDH-AS1 may affect the expression of FOXF1 and PKD1 in IDD [1].

Regulation

NA

Diseases

  • Invertebral Disc Degeneration[1].

Expression

UGDH-AS1 is co-expressed with several overlapping genes, including forkhead box F1 (FOXF1) and polycystin 1, transient receptor potential channel interacting [1].

Labs working on this lncRNA

  • Department of Spine Surgery, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
  • Department of Neurosurgery, Shanghai Fengxian District Central Hospital, Shanghai 201400, P.R. China.
  • Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, P.R. China.

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Qu ZG, Quan Z, Zhang Q, Wang ZY, Song QX, Zhuang XM et al. Comprehensive evaluation of differential lncRNA and gene expression in patients with intervertebral disc degeneration[J]. Mol Med Rep. 2018, 18(2):1504-1512.

Sequence

>gi|100885776|ref|NR_047679.1|Homo sapiens UGDH antisense RNA 1 (UGDH-AS1), long non-coding RNA

000001 TAGCAGCCCT CTCCCCGCTG CCCTGTCCTG GCCGAGGCAA AGGCCGCGTG CGCTCCGCGT CTGCCAGGCT TTAGGGCTGC 000080
000081 GCGGACACTG GGTGGGTGGT GGGCCGAGGC GACCGGAAGG TCCTGGCCGC CTTTCCGGTC TCCTCAGCAC CCTGGAGCGC 000160
000161 CGCCCTCGGG TTTCGGTCTC CTGGATCTGC GGGTCGGTCT CGGCGGGCGG ATTACTCCTC GCCCACAACC TCGAGGCCCC 000240
000241 GGGGTCAACC GCGCCCTCCG GGCCGGCAAC CCAGGGTTTA GTCAGATTCC TCCTGACCCA CCGCTTCTGG GAAAGAGGCG 000320
000321 CCTCCCGTCA GGAGGATGCT GAGTTCCTCA TGACTGGACC AGTGAGTGTC CACTCCCTGG TCCCTGGCGA GAGAGGCGGG 000400
000401 ACCCCCACGC CCTCCTGGCG CTCTTTGCAG AGATGTTCCT CAGGCCCAAT CCGGGATTTG GGATGTCTGT GCGTGCTGTG 000480
000481 GAGCAGAGAG TTTGCAACAT GGTCTCACTT TGTCACCCAG GCTGGAATGC ATTGGCATGA ACACGTCTCA CTGCAGCCTC 000560
000561 AACCTCCCAG GCTGAAGTGA CCCTCCAACT CTGCTTTCAC AGTAGCTGTG ATATGGTTTG GCTGTGTCCC CACCCACATC 000640
000641 TCATCTTAAA ACCCAGTGGG AGGAGGGATG TTCTCCCTTG GAACCAGGCC ACCATTCTAT GAGGAAGCCA AGCAGCCACA 000720
000721 TGAAAAGGCC GTATGTAGAC ATTCTAACTG ACAATACTAG CTAAGGTTCC AGCTACTCAC CAGCATCAAC TATCAGACAA 000800
000801 ATTCCTATCA TTAATAGAAG AAACTATATG CCAAGTGACA GCCAGTGAAG CAGAACAACA GGAGAAGACG GCGAAGCCAG 000880
000881 AAGCAAATTA TTTCAATGGA AGAAAAATCC CCTCTCCAGG TTGTTTTCAT TGAAAAGAGA GAAGAATCAA ATAGACGCAA 000960
000961 TAAAAAATGA TAAAGGGGAT ATCACCACCA ATCCCACAGA AATACAAACT ATCATCAGAG AATACTACAA ACGCCTCTAC 001040
001041 GCAAAGAAAC TAGAAAATCT AGAAGAAATG GTTAAATTCC TCGACACATA CACCCTCCCA AGACTAAACC AGGAAGAAGT 001120
001121 TGACTCTCTG AATAGACCAA TAACAGGCTC TGAAATTGTG GCAATAATTA ATAGCTTACC AACCAAAAAG AGTCCAGGAC 001200
001201 CAGATGGATT CACAGCCGAA TTCTACCAGA GGTACAAGGA GGAACTGGTA CCATTCCTTC TGAAACTATT CCAATCAATA 001280
001281 GAAAAAGAGG GAATCCTCCC TAACTCATTT TATGAGGCCA GCATCATCCT GATACCAAAG CCGGGCAGAG ACACAACCAA 001360
001361 AAAAGAGAAT TTTAGACCAA TATCCTTGAT GAACATTGAT GCAAAAATCC TCAATAAAAT ACTGGCAAAC CAAATCCAGC 001440
001441 AGCACATCAA AAAGCTTATC CACCATGACC AAGTGGGCTT CATTCCTGGG ATGTAAGGCT GGTTCAATAT ATGCAAATCA 001520
001521 ATAAATGTAA TCCAGCATAT AAACAGAACC AAAGACAAAA ACCACATGAT TATCTCAATA GATGCAGAAA AGGCCTTTGA 001600
001601 CAAAATTCGA CAACCCTTCA TGCTAAAAAC TTTCAATAAA TTAGGTATTG ATGGGACGTA TCTCAAAATA ATAAGAGCTA 001680
001681 TCTATGACAA ACCCACAGCC AATATCATAC TGAATGGGCA AAAACTGGAA GCATTCCCTT TGAAAACTGG CACAAGACAA 001760
001761 GGATGCCTTC TCTCACCACT CCTATTCAAC ATAGTGTTGG AAGTTCTGGC CAGGGCAATT AGGCAGGAGA AGGAAATAAA 001840
001841 GGGTATTCAA TTAGGAAGAG GAAGTCAAAT TGTCCCTGTT TGCAGATCAC ATGATTGTAT ATCTAGAAAA CCCCATTGTC 001920
001921 TCAGCCCAAA ATCTCCTTAA GCTGATAAGC AACTTCAGCA AAGTCTCAGG ATACAAAATC AATGTACAAA AATCACAAGC 002000
002001 ATTCTTATAC ACCAATAACA GACAAACAGA GAGCCAAATC ATGAGTGAAC TCCCATTCAC AGTTGCTTCA AAGAGAATAA 002080
002081 AATACCTAGG AATCCAACTT ACAAGGGATG TGAAGGACCT CGTCAAGGAG AACTACAAAC CACTGCTCAA TGAAATAAAA 002160
002161 GAGGATACAA ACAAATGGAA GAATATTCCA TGCTCATGGG TAGGAAGAAT CAATATCATG AAAATGGCCA TACTGCCCAA 002240
002241 GGTAATTTAT AGATTCAATG CCATCCCCAT CAAGCTACCA ATGACTTTCT TCATAGAATT GGAAAAAACT ACTTTAAAGT 002320
002321 TCATATGGAA CCAAAAAAGA GCCCGCATTG CCAAGTCAAT CCCAAGCCAA AAGAACAAAG CTGGAGGCAT CACGGTACCT 002400
002401 GACTTCAAAC TATACTACAA GGCTACAGTA ACCAAGACAG TATGGTACTG GTACCAAAAC AGAGATATAG ATCAATGGAA 002480
002481 CAGAACAGAG CCCTCGGAAA TAACGCCGCA TATCTACAAC TGTCTGATCT TTGACAAACC TGAGAAAAAC AAGCAATGGG 002560
002561 GAAAGGATTC CCTATTTAAT AAATGGTGCT GGGAAAACTG GCTAGCCATA TGTAGAAAGC TGAAACTGGA TCATTTCCTT 002640
002641 ACACCTTACA CAAAAATTAA TTCAAGATGG ATTAAAGACT TAAACGTTAG ACCTAAAACC ATAAAAACCC TAGAAGAAAA 002720
002721 CCTAGGCATT ACCATTCAGG ACATAGGCAT GGGCAAGGAC TTCATGTCTA AAACACCAAA AGCAATGGCA ACAAAAGCCA 002800
002801 AAATTGACAA ATGGGATCTA ATTAAACTAA AGAGCTTCTG CACAGCAAAA GAAACTACCA TCAGAGTGAA CAGGCAACCT 002880
002881 ACAAAATGGG AGAAAATTTT TGCAACCTAC TCATCTGACA AAGGGCTAAT ATCCAGAATC TACAATGAAC TCAAACAAAT 002960
002961 TTACAAG
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