ACTR3-AS1

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ACTR3-AS1, a set of biomarkers for the prognosis of patients with GBM,enabling a moreaccurate prediction of survival and revealingmorebiological functions.

Annotated Information

Approved Symbol

ACTR3-AS1

Approved Name

ACTR3-AS1: ACTR3 antisense RNA 1, AC104653.1

Characteristics

ACTR3-AS1 is a long noncoding RNA with esemble id ENSG00000115091, and is located on chromosome 2q14.1 [1].

Function

ACTR3-AS1 is enriched with ion binding, transport, cell-cell signaling, plasmamembrane parts, and more, and they were mainly related to neuroactive ligand-receptor interaction pathway, calcium signaling pathway, and the mitogen-activated protein kinase signaling pathway [1].

Regulation

NA

Diseases

  • Glioblastoma [1].

Expression

ACTR3-AS1 is expressed in brain tissues [1].

Labs working on this lncRNA

  • Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
  • Department of Neurosurgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People's Republic of China.

References

  1. ↑ 1.0 1.1 1.2 1.3 Lei BX, Yu L, Jung TA, Deng YF, Xiang W, Liu YW et al. Prospective Series of Nine Long Noncoding RNAs Associated with Survival of Patients with Glioblastoma[J]. J Neurol Surg Part A. 2018, 79(6):471-478.

Sequence

>gi|101060091|ref|NR_110174.1|Homo sapiens ACTR3 antisense RNA 1 (ACTR3-AS1), long non-coding RNA AGTAACACATGACATCTTTCTCCCTCGAATTAAAATGTGACTTGGTTCACCGGTTAAAACGCAGAGGGAG ATGGAAATGACCAGGAGTCGAAAGGAGAAGATAAGAGTGCAGTGGTGCAGTCATGGCTCACTGCAGCGTC TGCCTCCTGGACTCAAAGAATCCTCCTACCTCAGCCTCCCAAGTAGCTAGGACCACAGAGTTGTGCTCTC CTGCAGCGTTTTGCGGACGGCTGGCTATCTTACCCAGAATCAATCACACTGGGACACTGAAAAAAAAAAA AAAGGAAAAAAGAGCGAGGGAGTAATTCTAGCCTGTTTTTACAAGAACACAGTGGCTATAGACAGTGCCA GTGTGAAGATGACTCAGCAAACGTGGAGAACCAAAGATTCTAGGGCAGCACCAAAACTGGGAAAGCAATT ACAGCAGAAGTTGCCTTCCCCATGGTAGCTTAGCAACTTCGTGTCTCTCCAAGGCAGAGAGGAAAATCAA GTCTAACAGGCCTTCCCGAAGGCTAGGTGTGAAATACCAGAAGCCATCTTTGTTTCTGGCGATGTCACTA AATAAGTATTTGTTGATATAAAGTATTACA

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