LINC02604

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LINC02604 is a long noncoding RNA and serve as a prognostic biomarker in glioblastoma.

Annotated Information

Name

LINC02604: long intergenic non-protein coding RNA 2604 (HGNC nomenclature), lncHERG [1].

Characteristics

LINC02604 is one exon transcript of 2195 bp bp long non-coding RNA (GenBank), located on human chromosome chr7q11.21.

Function

LINC02604 depletion impairs tumor propagation in vivo. [1]

LINC02604 depletion impaired proliferation, migration and invasion of glioblastoma in vitro and in vivo. Higher expression of LINC02604 in patients with glioblastoma indicated lower survival rate and poorer prognosis [1].

LINC02604 can serve as a sponge for miR-940 which is a tumor suppressor in cervical cancer [1].

Expression

LINC02604 is overexpressed in in glioblastoma than non-tumor tissues [1].

Regulation

Please input information here.

Diseases

  • Glioblastoma (GBM) [1]

Labs working on this lncRNA

  • Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China.[1]

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Shi J, Wang YJ, Sun CR, Qin B, Zhang Y & Chen G. Long noncoding RNA lncHERG promotes cell proliferation, migration and invasion in glioblastoma[J]. Oncotarget. 2017, 8(64):108031-108041.

Sequence

>gi|644794|ref|NR_136637.1| Homo sapiens long intergenic non-protein coding RNA 2604 (LINC02604), long non-coding RNA

000001 TCTGAACATC CTCCTGTGAC TCGGCTCCTG CCCAGCTCCC AGCGGCCTCC GTAGACCCGA AGCCTCCTCC GGTCCAGCTC 000080
000081 TCCAGGCCTG CCTCCTGCCT CGTGGCGGCC TTCCCCGGCC ATGCTCGTGC CGGCTTCCCG GCAGCCTCCA CGAGCCCGGC 000160
000161 TCCTGCCTCA CGCGGGCCCC TCCAGGCCCA GCTCGTGCCT CGCGGCGGCC TCTCCAGGCC CGGCTCCCGC CCAGCCCGAC 000240
000241 GGCGTCTCCC AGCCCAAGGC TCCCTTCCTC AACGTCGGCC CCTCTGGGCC CAGCTCCTGC CTCCCGCTGA TGGCCTGTGC 000320
000321 GGGCCCACCC GAGGCGGCCC GAAGTCGGCC TCGCCAGGCC CAGCTCCTGC CTGGCGTAGG CCCCTGGGGG CACGGCCTCT 000400
000401 GCCCCACAGT GGCCCCTCCG GGCCCAGCTC GTGCCTCGGC TTGGCCGCCT CAGGCCCAGC TCCTGCCTGT GGGCGGCCTC 000480
000481 TCTCCAGACC CGGCTCTCGC CTCCCGGCAT CCTCTCCAGG CCCAGAGCTG TTTCCAGTTG CTAGACCATT TTTGTGCCTG 000560
000561 CCTCGTTGCA GCATCTCCAA GCCCAGCTTT TGCTTTTCTG CAGTTTCTTG AGGCCGAACT CCATTTTTCG AATGGCTTAT 000640
000641 TTAGGCCCAG CTCTTGCGTT TGCATTGTCC CTTCAGGCCC AGAACTTTCT CACGTCATCG TCACCAGGCC TAGCTTCTGC 000720
000721 ATCTGGTCAG CCTTTTAAGG CCCAGCTTTT GCCTCATAAA CTCAGCTCCT GTTTAATGGC GGCCTCCCAG GTCCCACCTT 000800
000801 CTGCCTTCCT GTGTCCACTC CAGGCCCAGC TACTGCCTTG GTGCTCTTTT TAAGTCAATA ATTTTTTCCA GTCGACCTCT 000880
000881 CCAGGCCCAA CTTGTACCTC TGAGTGTCCT CTAGGATCTC AGCTTCTGCC TAACAATGAC CTCTTTAGAC TCAGCTCATT 000960
000961 TTCACTGCTA CATCTTCAAG CCATTCTCCT GCCTCTTGGC AACCTCTAGT GGCCCAGCTT CTGCCTCACA GCAGCCTCTC 001040
001041 CATGCATGCC TAGCTCCTGC CTCTTTAGGG AACTTACAGG CCTAAAACTT TCTTAATTTG GGCTTCTCAG GCCCAGCTCC 001120
001121 TGCCTTCTGT TGGCCTCTAC AGGCCTGGCA TCATCCTTTC AACAGCCTCT TTAGGCCCGG CCTCTCCAGG ACCAAAACAT 001200
001201 CCTTAAGTCA ACCTCACCAG GCCCGGCTCC TGTCTCCTTG CGGCCTCCAG AGGCCGAGCT TTTGCCTGCC AATGGCCTCT 001280
001281 CTAGCCCCAG CTTTTGCCTG CCAATGGCCT CTCTAGCCCC AGCTTCTGCC TTTCATCGGT CTCTCCAGGC TTAGCTCCTT 001360
001361 TCTCTTCACG GCCTCTGCAG GCCTAAAACT TCCTCAATTT GGCATCTCCA GGCCCAGCTC CTGCCTCCAG GCCGCCTCTG 001440
001441 CAGGCCTATC TCAAGCCTTA CAACAGCCTC TTTACCCCCA GCTCCTTTCT CCGACTTGTC TCTCCAGGCC TAGAACTTCC 001520
001521 TCATGTTTAC CTCACCAGGC CCACCTCCTG CCTTCCAGTA GCGTCTACAA GTTTGGCTCC TGCCTCCCAT GGATCTCTCC 001600
001601 AGGCCCCAAA CTTTCTCAAG TCAACCTCAC CAGGCCCGGC TTCTCCCTTT CATCAGCCTT CCAAAGGCCA GCTTTTGCTT 001680
001681 CATGTCTGCC TTCCGAGTCC CAGCTCCTGT TTTATGGCAG CCTCCTGAGG CCCAGCTCCT GCCTCCTAGT GGCCTCTTTT 001760
001761 GGCCCAACTC TTTCCTCACC AGGGCCTTCC AGACCACGTT CCTGCCTTTT AGCAGCCACT ACAGGCCCAG CTTTGCGTCC 001840
001841 TTTCAAGAGT CCTGCCTCAC AGTGGCCTCC CAAGGGCAAC TTTCTGCCTC ATGTCAGCCT CTTGTGCCCT GGTCCTGCTT 001920
001921 CCTGGTAGAC TCTGCAGGCC CTGCTCCTGC CTTACGTTGC CCCTTTTATA AAGATCCAGT TCCTGCCTCC TGGCTGCCTC 002000
002001 TATGAGCCCA AATCCTGCCT AACAACAACC TGTTTTTGCC CAGCTCCTGC TTCCTGGCAG CCTCCTTAGG CCAAAAATTT 002080
002081 CCTTCAGTTG ACCTCTCCAG GCCCAGCTCC TGCCTCTCAG CACCCTCTTT AGGCCCAGCT CCTGCCTTAA TAAATTTGAA 002160
002161 TAAATTATTG TTATGTGAAA AAAAAAAAAA AAAAA
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