MAP3K2-DT

MAP3K2-DT is a long noncoding RNA that may contribute to the occurrence of polycystic ovary syndrome (PCOS) and affect oocyte development.

Annotated Information

Name

MAP3K2-DT: MAP3K2 divergent transcript (HGNC nomenclature), ENST00000433673 ^[1].

Characteristics

MAP3K2-DT is 3445 bp long non-coding RNA, located on human chromosome 2q14.3.

Function

Please input information here.

Expression

The expression levels of the five selected lncRNAs (XLOC_011402, ENST00000454271, ENST00000433673, ENST00000450294, and ENST00000432431) were examined by qRT-PCR in a cohort of CC samples isolated from an additional 30 PCOS and 30 normal patients. ^[1]

MAP3K2-DT is upregulated lncRNA in polycystic ovary syndrome (PCOS) ^[1].

Regulation

Please input information here.

Diseases

Polycystic ovary syndrome (PCOS) ^[1]

Labs working on this lncRNA

Reproductive Medicine Centre, Affiliated Hospital of Qingdao Medical University, Yuhuangding Hospital of Yantai, 20 Yuhuangding Road East, Yantai, Shandong 264000 People’s Republic of China.^[1]

References

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Huang X, Hao CF, Bao HC, Wang MM & Dai HG. Aberrant expression of long noncoding RNAs in cumulus cells isolated from PCOS patients[J]. J Assist Reprod Gen. 2016, 33(1):111-121.

Sequence

>gi|100506922|ref|XR_001739702.2| Homo sapiens , MAP3K2 divergent transcript (MAP3K2-DT), long non-coding RNA

000001  GTTCCGTGTG CGCGGCGCAT ACGCACCTGG GTTGTCTCGA GCCTGCGGTA GTGGCCAGAT CCCAGACATC CGAGTAGATC  000080
000081  CCGTGAAAAG CTTCTTCTTG GTTTCTTCGT ACATTCTGGA TCCACCCCTT TCATGCATAT TCCAGACCAC ATTTCCACTG  000160
000161  GAGCAGTTGA AATGAGAGAG ATGGGAATGG GACTCACCCG AACCAGAGGA ATTTTTATTA CAGACCCATT AACAGAGGTG  000240
000241  TCAAAGTCAC AGGAACAAGG ATGTGCACCT CAGAAACACA GAGGCTAGCC TGGCTGAAGC TCAGCTGCAC AGAGTCTGTC  000320
000321  CTGAGAAGCA GAATGCCACT GTCCCCTGGG CCCTCCAGAC TGCCAAGGCT GCTCAGTTTC AGAGAGCAGG CTCCCTGTGG  000400
000401  CCTCACACGC CGGCTGCCAG CTGGGCCAGG TAACTCTGGC CAGGCTGCAC TGTGAAGAAC ACGAGAGTCG GCGGAGACCT  000480
000481  GTGCCTGCTC TTCTCAGCCT CAATGTCTGG AAGACAAAAA AAGGCATCCT GCTCCCAAGA TTGTGGTGGA GGCCAGCAGG  000560
000561  GTGACGCACA TGAAAGCCAC TGGAGATAGA TGGCACTTGT TCCCACCCAC TGCCCACAAC AGGCCCAGGA CTGCCTCAGC  000640
000641  CCCGGTGGAC CCCAGAGCCA GCAGGCCCTT CAGAATGGAA GGTGCCAAAC ACCATCGGAA GGCGTGGTTC TTTTCAGAGA  000720
000721  ACCAGACTCT GAGACTGTGG CCTCCCACTA TGAGTCACCA CCTCTGATTC CTGAGGTCCC CTCCAGTCAT TGGCTCTCTC  000800
000801  CCAAGCCAGC CAGCTGATCA GCCTTGAGGA CAGCAGAGTG TCTGCCAAGA GAGATCTGTG AAGTTTCCCA TCACCGTGGC  000880
000881  AGTCCACAAT GTGAAGCCCC TGAGGCCACC CTTCTCCATG TGTCCCCCAC ACTGTCCCTG ACCCTCCCAC CATCCTAGAA  000960
000961  AACCAGCCTC CCAGGTCCTC TGTCATGGAA GTAATTTACA GCAAGGCAGA AAGAGCTGAA AGATTTATAA ATGTGTAAAA  001040
001041  TTTACAAAGG TGTTTCTTTC TTTCTTTCTT TCTTTTTTTT TTTTTTTTTT TTTGAGGCAG AGTCTCACTC TGTTGCCCAG  001120
001121  GCTGGAGTGC AGTGGCACAA TTTTGGCTCA CTGCAACCTC CGCCTCCCGG GTTCAAGTGA TTCTCCTGCC TCAGCCTCCC  001200
001201  AAGTAGCTGG GATTACAGGT GCATGCCACC ACGCCTAGCT AATTTTTGTA TTTTTAGTAG AGACAGAGTT TTTTGCCATG  001280
001281  TTGGCCAGGC TGGTCTTGAA CTCCTGACCT CAGGTGATCT GCCTGCCTCA GCCTCCCAAA GTGCTGGGAT TACAGGCGTG  001360
001361  AGTCACCGTG CCCGGCCTAC AGAGGTGTTT CTGAGTGGAG AAACCACTGC CTGGTTGGAC TGACTGCCCA GTTCCACCAC  001440
001441  CCTGTGAGCC CATGAGTGAG CTCACTGCAC TTGTTATAGA CATCCTACCA CCAGCAGCCT GATTTTGCTG AGTCCGTAGC  001520
001521  TTACAACTCC AATCTCATGG CCCTGCCTTT CACCTCACTT GCTGCCTTAA AAACCTGCAG ACTGAGGTGG CGTAGAAGCT  001600
001601  GTGACATCCC AGTACCCAGA AGTTCATCTC ACACCCAGAT CTTGGTTTCT AAATGTCATT CTCTACTAAA AGGGACCAGG  001680
001681  GCTGGTACAG GAGAAGAGCA AGAGCTTGGA ATATCTTATA CCTGAGAGTA AGGAAGTGCT CAGAGAATCA CAGGAGCACG  001760
001761  TTAAAAGGAC ATAGAAGTCA GTTTAATGAG ACTGCTTCTG GCCAAAGTTG GAACACATCA AACATTAAAA CAATGATGGT  001840
001841  AATGGATTAG ATTCCATAGA ATAAAATCCT TGAGGACATA GTTATATAAA CATAACTGAG GAAGAAGGAA AAGCTCTCCC  001920
001921  TAACAGAATA ATACAACTAG TAAATGGGAA AGGAAAGGAG TTAGGAATTC ACGCTGGGTA TTGAAACTAG TGGGTGAAAG  002000
002001  CTCAATGAAT CGGATTCTTA GTCTCAATGT CTCTCCTCTC AATTTAGTAA TTATAGTGGA GTAATCATGA CTTTACAGTG  002080
002081  GAGAAACCTG GCCAACACTA CCTTCACAAC ACTAACAAAA ACCTTGCAGA CCTGCAGCCT AAGCTCCCAG AAGTCACCTG  002160
002161  CTGAAATGCC TTCAAAGAGT GACCTCT

[ref1-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Huang X, Hao CF, Bao HC, Wang MM & Dai HG. Aberrant expression of long noncoding RNAs in cumulus cells isolated from PCOS patients[J]. J Assist Reprod Gen. 2016, 33(1):111-121.

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