LINC02631

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LINC02631, a lncRNA that might be associated with Compounds containing hexavalent chromium [Cr(VI)] exposure[1].

Annotated Information

Name

Approved symbol: LINC02631

Approved name: long intergenic non-protein coding RNA 2631

Alias symbols: AC092620.3

HGNC ID: HGNC: 54112

Ensembl ID: ENSG00000237772

NCBI Gene: 114515520

Characteristics

LINC02631 was nonlinearly decreasing with the change of the DNA content of comet tails (Tail DNA), tail length (TLL), tail moment (TM) and Olive Tail Moment (OTM), and the fitting results of Tail DNA and TM were statistically significant (P <0.05)[1].

With the increase of Cr(VI) concentration, the expression of LINC02631 increased gradually, indicating that LINC02631 was likely to be candidate biomarkers for Cr(VI) exposure and DNA damage[1].

Function

Regulation

Diseases

Expression

Compared with the control group,LINC02631 was significantly up-regulated with increasing concentrations of Cr(VI) (P < 0.05)[1].

Evolution

Labs working on this lncRNA

  • Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, Beijing, China.

References

  1. 1.0 1.1 1.2 1.3 Hu G, Feng H, Long C, et al. LncRNA expression profiling and its relationship with DNA damage in Cr(VI)-treated 16HBE cells[J]. Science of The Total Environment, 2019, 655:622-632.

Sequence