FAM230A

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Annotated Information

Name

Approved symbo：FAM230A

Approved name：family with sequence similarity 230 member A

HGNC ID：HGNC:45045

Previous name:family with sequence similarity 230, member A

Alias symbol:DGCR15

RefSeq ID:NR_136560

Characteristics

FAM230A (NCBI ID 653203 and UCSC:ID uc062bir.1) (chr22:18487127–18500594) contains the very 3’ end section of the FAM230C sequence (nt positions 32771–37928) and does not have the Translocation Breakpoint Type A (TBTA) that consists of satellite DNA, Alu elements, and AT-rich sequences, however, this gene is believed to produce a nonsense-mediated mRNA decay transcript and thus does not appear to be a lincRNA gene. There is a putative protein gene with the same name, FAM230A (ENSG00000277870, chr 22: 18,422,244-18,500,594) but this gene has a gap of 50,000 bp in an unsequenced region in the middle of the gene; thus, characterization of this putative gene is premature. FAM230C is a case of high specificity in lincRNA gene formation by gene sequence duplication in different chromosomes [1].

Function

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Regulation

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Diseases

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Expression

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Labs working on this lncRNA

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References

  1. ↑ Delihas N. A family of long intergenic non-coding RNA genes in human chromosomal region 22q11. 2 carry a DNA translocation breakpoint/AT-rich sequence. PloS one. 2018, 13(4):e0195702.

Sequence

>gi|653203|ref|NR_136560.1 | Homo sapiens family with sequence similarity 230 member A (FAM230A), long non-coding RNA

000001 TTCCCAATGC AGATGACTTC CATCATACAG TCTTCAGCAA CCTTGAAAGA TTGGACAAGC TTCAGCCCAC TCTTGAAGCC 000080
000081 TCTGAGGAGT CTCTAGTTCA CAAGGACAGA GGAGATGGAG AGAGGCCAGT CAACGTGAGG GTGGTGCAGG TGGCCCCTCT 000160
000161 GAGGCATGAA TCTACTCCCC ATGAGGACAC CGTACACAAC ATCACTAACG AGGATGCCTC ACACGATATC ACTAACGAGG 000240
000241 ACGCTGTCCA CGGCATCGCT AACGAGGCCG CCGACAAGGG CAACGCCAAC GAGGACGCCG CCCAGGGCAT CGCCAACGAG 000320
000321 GACGCCGCCC ACGGAATCGC CAGCGAGGAC GCCGCCCAGG GCATCGCCAA CGAGGTCGCC GCCCAGGGCA TCGCCAACGA 000400
000401 GGACGCCGCC CAGGGCATCG CCAACGAGGA CGCCGTCCAG GGCATCGCCA ACGAGGACGC CGCCCACGGC ATCGCCAACG 000480
000481 AGGACGCTGC CCACGGCATT GCTAACGAGG ATGCCGTGCA CGGCATCGCT AATGAGGACT CCGTATACGA CATCGCTAAT 000560
000561 GAGGATGCCA TATATGACAT CGCTAATGAC ACCGTACAAG GCACGCTAAA GAGGACGCTG TACACGACAT CGCTAATGAG 000640
000641 GACACCATAC AAGGCATTGG TAATGAGGAC GTTGTATATG ACATCGCTAA CAAGGACACT CTACAAGCCG TCGCTAACAA 000720
000721 GGACACTGTA CACAACATCG CTAATGACGG CACCGTACAA GACATCACCA ATGAGGGCGC TTTATACGAC ATTGCTAATG 000800
000801 ATACCGACAA GGCACGCTAA CGCGGACACT GTACACGACA TCGCTAATGA GGACTCCGTA TACCACATCG CTAATGAGGG 000880
000881 TGCCGTATAT GACATCGCTA ATGACACCGT ACAAGGCACG CTAACGAGGA CGCTGTACAC GACATCGCTA ATGAGGACAC 000960
000961 CATACAAGGC ATCGGTAATG AGGACGCTGT ATACGACATC GCTAACGAGG ACACCATACA AGCCGTCGCT AACAAGGACA 001040
001041 CTGTACACAA CATCGCTAAT GACGGCACCG TACAAGACAT CACCAATGAG GGCGCTTTAT ACGACATTGC TAATGATACC 001120
001121 GACAAGGCAC GCTAACGTGG ACGCTGTACA CGACATTGCT AATGAGGACA CCGTATAAGA CATCGCTAGT AACTATCGCA 001200
001201 AGAACAAAAA ACCAAACACC GCATATTCTC ACTCATAGGT GGGAATTGAA CAATGAGATC ACATGGACAC AGGAAGGGGA 001280
001281 ATATCACATT CTGGGGACTG TTGTGGGGTG GGGGGAGGGG GGAGGGATAG CATCGGGAGA TATACCTAAT GCTAGATGAT 001360
001361 GAGTTAGTGG GTGCAGCGCA CCAGCGTGGC ACATGTATAC ATATGTAACT AACCTGCACA ATGTGCACAT GTACCCTAAA 001440
001441 ACTTAAAGTA TATATAAAAA AAAAAGACAT CGCTAGTGAG CACGCTGTAT ACGACATCGC TAATGAGGAC ACCATACAAG 001520
001521 GCATCGCTAA CGATGACGCT GTACACAACA TCACTAATGA TGACACCGTA TAAGACATCG CTAATTATGA CGCTGTATAC 001600
001601 GACATCGCTA ATGACACCGT ACGAGGCACG CTAACAAGGA TGCTGTACAC AACATCGCTA ATGAGGACAG TGTACAAGCC 001680
001681 ATCGCTAATG AGGACACTGT ATATGACATT GCTAACGAGG ACACTGTACA AGGCATTGCT AACGAGGACG CTGTACACAA 001760
001761 CATCGCTAAT GAGGACACCA TATAAGACAT CACCAATGAG GATGCTCTAT ATGACATCGC TAATGACACC CACAAGGCAT 001840
001841 GCTAACGAGG ACGCTGTAGA CGACATTGCT TATAAGGACA CCGTACAAGA CATCGCTAAC GAGGACGCTG TATACGACAT 001920
001921 CGCTAATGAG GACGTTGTAT ATGACATCGC TAATGAGGAT GCTTTACAAG ACATAGCGAA TGAGGTTGCT GTATATGACA 002000
002001 TCGCTAATGA GGACATTGTA TATGACATCG CTAATGAGGA CGCTCTATAC GACATCACTA ATGAGGACGC TGTATACAAC 002080
002081 ATCGCTAATG AGGACGCTGT ATATGGCATC GCTAATGAGG ATGCTGTATA CGAATTCGCT AATAAGGACG CTGTATATGA 002160
002161 CATTGCTAAT GAGGACACTG TACAAGACAT CTGTAAAAAA GAAGATGCTG CCAATGA