GMDS-DT
GMDS-DT acts as a tumor suppressor gene to affect the development of LUAD.
Contents
Annotated Information
Name
Approved symbol:GMDS-DT
Approved name:GMDS divergent transcript
HGNC ID:HGNC:48993
Previous name:GMDS antisense RNA 1 (head to head)
RefSeq ID:NR_046229
prev_symbol:GMDS-AS1
Characteristics
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Function
Upregulated GMDS-DT can significantly inhibit the proliferation of LUAD cells and promote cell apoptosis in vitro and in vivo. [1]
Regulation
GMDS-DT can act as a ceRNA to upregulate the expression of CYLD by sponging miR-96-5p. [1]
Expression
The expression of lncRNA GMDS-DT was significantly reduced in lung adenocarcinoma (LUAD) tissues and cells. [1]
Diseases
lung cancer[1]
Labs working on this lncRNA
- Department of Respiratory Medicine, Jinling Hospital, Second Military Medical University, Nanjing, China.[1]
